Epic Bio

Epic Bio (legally Epicrispr Biotechnologies, Inc.) is a clinical-stage genetic medicines company in South San Francisco, California, founded in 2018 by Stanford CRISPR pioneer Stanley Qi, Ph.D. It develops epigenetic editing therapies that modulate gene expression without cutting DNA, built on its proprietary Gene Expression Modulation System (GEMS) platform — a combination of ultracompact DNA-binding proteins (CasMINI, CasONYX), tailored guide RNAs, and a large library of transcriptional and epigenomic modulators. Its lead program EPI-321 is in first-in-human clinical study for facioscapulohumeral muscular dystrophy (FSHD), with preclinical programs in alpha-1 antitrypsin deficiency and heterozygous familial hypercholesterolemia. The company is a therapeutics developer, not a software vendor: it publishes a corporate and scientific website but no developer program, public API, SDK, or machine-readable specification.

Epic Bio is profiled on the APIs.io network. Tagged areas include Company, Biotechnology, Genetic Medicine, Gene Editing, and CRISPR.

Epic Bio’s developer surface includes engineering blog, support, and 8 more developer resources.

9.6/100 minimal ▬ flat Agent 3/100 human only Full breakdown ↓
scored 2026-08-17 · rubric v0.11.0
0 APIs
CompanyBiotechnologyGenetic MedicineGene EditingCRISPREpigeneticsTherapeuticsLife SciencesClinical Stage

Kin Score

Kin Score Kin Score How this is scored →
scored 2026-08-17 · rubric v0.11.0
Composite quality — 9.6/100 · minimal
Contract Quality 0.0 / 21
Developer Ergonomics 1.1 / 17
Commercial Clarity 1.8 / 17
Operational Transparency 0.0 / 11
Governance 0.0 / 10
Discoverability 4.9 / 9
Regulatory Posture 1.9 / 15
Agent readiness — 3/100 · human only
Machine-Readable Contract 0 / 18
Agentic Access Contract 0 / 10
MCP Server 0 / 12
Machine-Readable Auth 0 / 10
Idempotency 0 / 9
Stable Error Semantics 0 / 8
Request/Response Examples 0 / 7
Rate-Limit Signaling 7 / 7
Typed Event Surface 0 / 6
Agent Skills 0 / 5
Well-Known Catalog 0 / 4
Consent & Bot Identity 0 / 3
A2A Agent Card 0 / 8
Dry-Run / Simulate Mode 0 / 4
Regulatory Posture applies to this provider. Its tags matched the Health regime, so Regulatory Posture carries 15 points of the composite. If this regime is wrong for your business, say so on your provider repo — the applicability map is public and we will correct it.
The six quality facets above are damped to 85 points between them, because the conditional facet above carries the other 15. That is why each facet's contribution is shown against a damped maximum: raising a quality facet moves the composite by 85% of its nominal weight, not 100%. The full arithmetic is at apis.io/rating/.
Improve this rating by publishing the missing artifacts — every area above can be raised, and the full rubric is at apis.io/rating/. This rating is computed from github.com/api-evangelist/epic-bio: open an issue to ask a question, or submit a pull request to add artifacts. Want it done for you? Prioritized profiling — $2,500 →

Pricing Plans 1

Published pricing tiers and plan structures.

Rate Limits 1

Documented rate limits and quota policies.

Epic Bio Rate Limits

0 limits

RATE LIMITS

Security Posture 1

Authentication, domain security, vulnerability disclosure, and trust-center signals.

Epic Bio Domain Security

TLSv1.3

SECURITY

Resources

Agent Surfaces 1

MCP servers, agent skills, and machine-readable catalogs

Access & Security 1

Authentication, authorization, and security posture

Operate 1

Status, limits, changes, and where to get help

Commercial 1

Pricing, plans, and the legal terms of use

Company 5

The organization behind the API

Other 1

Properties that don't map to a standard resource type

Source (apis.yml)

apis.yml Raw ↑
aid: epic-bio
name: Epic Bio
description: 'Epic Bio (legally Epicrispr Biotechnologies, Inc.) is a clinical-stage genetic medicines company in South San
  Francisco, California, founded in 2018 by Stanford CRISPR pioneer Stanley Qi, Ph.D. It develops epigenetic editing therapies
  that modulate gene expression without cutting DNA, built on its proprietary Gene Expression Modulation System (GEMS) platform
  — a combination of ultracompact DNA-binding proteins (CasMINI, CasONYX), tailored guide RNAs, and a large library of transcriptional
  and epigenomic modulators. Its lead program EPI-321 is in first-in-human clinical study for facioscapulohumeral muscular
  dystrophy (FSHD), with preclinical programs in alpha-1 antitrypsin deficiency and heterozygous familial hypercholesterolemia.
  The company is a therapeutics developer, not a software vendor: it publishes a corporate and scientific website but no developer
  program, public API, SDK, or machine-readable specification.'
image: https://epicrispr.com/wp-content/uploads/2024/11/epicrispr-logo-768x452-1.png
url: https://raw.githubusercontent.com/api-evangelist/epic-bio/refs/heads/main/apis.yml
x-type: company
x-source: harvest:secondary-market
x-tier: stub
x-tier-reason: harvest
specificationVersion: '0.20'
created: '2026-08-12'
modified: '2026-08-12'
tags:
- Company
- Biotechnology
- Genetic Medicine
- Gene Editing
- CRISPR
- Epigenetics
- Therapeutics
- Life Sciences
- Clinical Stage
apis: []
maintainers:
- FN: Kin Lane
  email: kin@apievangelist.com
- FN: APIs.json
  email: info@apis.io
common:
- type: Website
  url: https://epicrispr.com/
- type: About
  url: https://epicrispr.com/science/
- type: Blog
  url: https://epicrispr.com/news/
- type: BlogRSS
  url: https://epicrispr.com/feed/
- type: Support
  url: https://epicrispr.com/contact/
- type: PrivacyPolicy
  url: https://epicrispr.com/privacy-policy/
- type: Careers
  url: https://epicrispr.com/careers/
- type: Sitemap
  url: https://epicrispr.com/sitemap_index.xml
- type: DomainSecurity
  url: security/epic-bio-domain-security.yml
- type: LLMsTxt
  url: llms/epic-bio-llms.txt
x-enrichment:
  date: '2026-08-12'
  status: minimal
  artifacts_added: 5
  pass: local-v1
x-coverage:
  state: none
  reason: not-a-software-company
  detail: Epic Bio is Epicrispr Biotechnologies, a clinical-stage epigenetic-editing therapeutics company whose only host
    is a WordPress marketing site — the similarly named epic.bio belongs to Guerbet and open.epic.com belongs to Epic Systems,
    so neither of those API surfaces is this company's.
  evidence:
  - url: https://epicrispr.com/openapi.json
    status: 404
  - url: https://epicrispr.com/.well-known/agent-card.json
    status: 404
  - url: https://epicrispr.com/llms.txt
    status: 404
  - url: https://github.com/epicrispr
    status: 404
  checked: '2026-08-12'