Defiance International

Defiance International (defianceinternational.io) is an online supplier of research-use-only (RUO) chemical sequences and peptides that pairs each released lot with a checkable Certificate of Analysis record, including purity by HPLC, and a lot verifier at /coa/verify. Alongside its catalog, research library, trust center and journal, it publishes machine-readable data for agents -- an llms.txt index, an AI index of JSON catalog, sequence, evidence and policy documents, an OpenAPI description at /ai/openapi.json, and a read-only public Model Context Protocol endpoint at /mcp.

Defiance International publishes 7 API contracts indexed on the APIs.io network, including Catalog API, Content API, Documents API, and 4 more. Tagged areas include Company, Research Chemicals, Peptides, Certificate of Analysis, and Laboratory Supplies.

The Defiance International catalog on APIs.io includes 1 JSON-LD context and 1 Spectral governance ruleset.

Defiance International’s developer surface includes authentication, documentation, engineering blog, support, and 28 more developer resources.

🌐 Visit website 📡 Profile data on GitHub

40.7/100 developing Agent 36/100 agent ready Full breakdown ↓
scored 2026-11-06 · rubric v0.27.0 · Show this score on your site →

1 published contract 1 MCP Servers 4 Agent Skills

CompanyResearch ChemicalsPeptidesCertificate of AnalysisLaboratory Supplies E-Commerce MCP

Kin Score

Kin Score How this is scored →
scored 2026-11-06 · rubric v0.27.0

Composite quality — 40.7/100 · developing

Contract Quality 11.9 / 21

Developer Ergonomics 5.2 / 17

Access Clarity 4.9 / 17

Operational Transparency 1.7 / 11

Contract Governance 2.2 / 10

Discoverability 6.1 / 9

Regulatory Posture 5.3 / 15

Agent readiness — 36/100 · agent ready

Machine-Readable Contract 18 / 18

Agentic Access Contract 10 / 10

Documented Reversibility 0 / 6

MCP Server 12 / 12

Machine-Readable Auth 10 / 10

Idempotency 0 / 9

Stable Error Semantics 8 / 8

Request/Response Examples 0 / 7

Rate-Limit Signaling 7 / 7

Typed Event Surface 0 / 6

Agent Skills 5 / 5

Well-Known Catalog 0 / 4

Consent & Bot Identity 0 / 3

A2A Agent Card 8 / 8

Dry-Run / Simulate Mode 0 / 4

Delegated User Identity 0 / 6

Protected Resource Metadata 0 / 5

Registration Without a Human 0 / 6

Agentic Commerce Well-Known Document 0 / 5

Pagination 5 / 5

Distinct Operations 3 / 3

MCP Tool Quality 6 / 6

Regulatory Posture applies to this provider. Its tags matched the Horizontal (data, software, accessibility, platform) regime, so Regulatory Posture carries 15 points of the composite. If this regime is wrong for your business, say so on your provider repo — the applicability map is public and we will correct it.

Create-or-Update Ergonomics could not be measured. We hold no machine-readable contract for this provider to read, so there is nothing to measure a write surface against. Excluded rather than scored zero: never-measured and measured-empty are different facts. Publishing an OpenAPI is what makes this facet — and several others — scorable at all.

The six quality facets above are damped to 85 points between them, because the conditional facet above carries the other 15. That is why each facet's contribution is shown against a damped maximum: raising a quality facet moves the composite by 85% of its nominal weight, not 100%. The full arithmetic is at apis.io/rating/.

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Agent readiness — checks not met, largest first (exact, from this profile):

Idempotency +9 pts — OpenAPI mutating operations declare an idempotency key — a header, a request-body property, or a named de-duplication token whose own description says so (verified); else common[].type matches /idempoten/i (documented)
Request/Response Examples +7 pts — share of operations carrying request/response examples; else an Examples / Code Samples link
Registration Without a Human +6 pts — a `registration_endpoint` in the served RFC 8414 / OIDC discovery document
Delegated User Identity +6 pts — a served discovery document listing authorization_code in grant_types_supported (served), else an oauth2 authorizationCode flow or openIdConnect declared in an OpenAPI (documented)
Typed Event Surface +6 pts — AsyncAPI document, OR webhooks/callbacks objects in the as-published OpenAPI, OR common[].type includes Webhooks
Documented Reversibility +6 pts — a reversal operation in the contract, graded up when a window is documented too

5 more unmet checks in the Agent Readiness table above.

Kin Score — facets with the most composite points still available (weight × headroom):

Access Clarity scores 28.9 — up to +14.2 composite points
Developer Ergonomics scores 30.4 — up to +13.9 composite points
Contract Quality scores 55.9 — up to +11.0 composite points

Each check links to what satisfies it. Publish the artifact, or tell us where it already lives, and the score moves on the next scoring run.

Improve this rating by publishing the missing artifacts — every area above can be raised, and the full rubric is at apis.io/rating/. Every facet and dimension name above is a link: it opens that measurement's own page — what it means, the exact checks that feed it, how the whole catalog distributes on it, and the providers at the top of it. This rating is computed from the provider profile at artifacts.apis.io/defianceinternational-io/apis.yml: open an issue on github.com/api-evangelist/defianceinternational-io to ask a question or point us at an artifact you publish. Submit an artifact on GitHub — free → Manage your own listing — the Influence plan, $499/mo →

Standards implemented 3

Standards this provider implements or carries. De facto ones are profiled and measured by the API Commons; formal ones come from the standards directory and are linked by the provider's own tags. The evidence column says how each claim was established — not that it was made.

Agent2Agent

measured — observed by APIs.io (flavored)

Model Context Protocol (MCP)

measured — observed by APIs.io (documented)

OpenAPI

measured — observed by APIs.io (published)

APIs 7

Individual APIs this provider publishes, each with its own machine-readable definition.

Defiance International Catalog API

The catalog API from Defiance International — 20 operation(s) for catalog.

Defiance International Content API

The content API from Defiance International — 12 operation(s) for content.

Defiance International Documents API

The documents API from Defiance International — 22 operation(s) for documents.

Defiance International Machine Documents API

The machine-documents API from Defiance International — 10 operation(s) for machine-documents.

Defiance International Platform API

The platform API from Defiance International — 10 operation(s) for platform.

Defiance International Research Register API

The research-register API from Defiance International — 4 operation(s) for research-register.

Defiance International Studies API

The studies API from Defiance International — 3 operation(s) for studies.

Scroll for all 7

MCP Servers 1

Model Context Protocol servers that expose these APIs to AI agents.

Defiance International MCP Server

Remote MCP server at defianceinternational.io; 5 tools listed.

MCP SERVER

Agent Skills 4

Packaged agent skills for driving this provider's APIs from an AI assistant.

check-coa-and-safety-documents

AGENT SKILL

look-up-a-sequence

AGENT SKILL

review-sequence-evidence-and-studies

AGENT SKILL

verify-a-publication

AGENT SKILL

Defiance International API pricing

Pricing Plans 1

Published pricing tiers and plan structures.

Defianceinternational Io Plans Pricing

0 plans

PLANS

Rate Limits 1

Documented rate limits and quota policies.

Defianceinternational Io Rate Limits

2 limits

RATE LIMITS

Semantic Vocabularies 1

JSON-LD contexts and semantic vocabularies used across these APIs.

Defianceinternational Io Context

120 classes · 114 properties

JSON-LD

Spectral Rules 1

Spectral governance rulesets for linting and validating these APIs.

Defiance International API Rules

45 rules · 32 errors 4 warnings 9 info

SPECTRAL

OpenAPI Overlays 1

Overlays applied on top of this provider's contracts. Each card says who wrote it: a document the provider publishes, or one API Evangelist derived or generated.

Defianceinternational Io Openapi Overlay

8 actions · documentation · defianceinternational-io-openapi.yml

DERIVED

JSON Schema 6

Standalone JSON Schema definitions for this provider's data models.

getEvidencePackage.200

0 properties

JSON SCHEMA

getSequenceLotCertificate.200

0 properties

JSON SCHEMA

listProductStudiesV2.200

9 properties

JSON SCHEMA

listResearchRecords.200

0 properties

JSON SCHEMA

listSequenceStudies.200

0 properties

JSON SCHEMA

listStudiesV2.200

9 properties

JSON SCHEMA

Security Posture 3

Authentication, domain security, vulnerability disclosure, and trust-center signals.

Defianceinternational Io Authentication

1 scheme

SECURITY

Defianceinternational Io Domain Security

TLSv1.3 · HSTS · DMARC

SECURITY

Defianceinternational Io Vulnerability Disclosure

security.txt · contact published

SECURITY

Agentic Access 1

Recommended x-agentic-access execution contracts for AI agents.

Defianceinternational Io Agentic Access

81 operations

81 operations · 0 acting

AGENTIC

Resources

Documentation 1

Reference material describing how the API behaves

Documentation

Documentation

Agent Surfaces 6

MCP servers, agent skills, and machine-readable catalogs

AgenticAccess

AgentSkill

LLMsTxt

MCPServer

WellKnown

LLMsTxt

Design & Contract 8

Pagination, idempotency, versioning, errors, and events

Spectral

JSONLD

Vocabulary

DataModel

Conventions

Lifecycle

ErrorCatalog

Conformance

Scroll for all 8

Build 1

SDKs, sample code, and the tooling you integrate with

ToolCrosswalk

ToolCrosswalk

Access & Security 6

Authentication, authorization, and security posture

Security

Security

Authentication

Authentication

SecurityTxt

SecurityTxt

VulnerabilityDisclosure

VulnerabilityDisclosure

DomainSecurity

DomainSecurity

TrustCenter

TrustCenter

Operate 2

Status, limits, changes, and where to get help

RateLimits

RateLimits

Support

Support

Commercial 2

Pricing, plans, and the legal terms of use

TermsOfService

TermsOfService

PrivacyPolicy

PrivacyPolicy

Company 2

The organization behind the API

Website

Website

Blog

Blog

Other 4

Properties that don't map to a standard resource type

Overlay

AgentCard

Hosts

Vendors

Source (apis.yml)

aid: defianceinternational-io
name: Defiance International
description: Defiance International (defianceinternational.io) is an online supplier of research-use-only (RUO) chemical sequences
  and peptides that pairs each released lot with a checkable Certificate of Analysis record, including purity by HPLC, and
  a lot verifier at /coa/verify. Alongside its catalog, research library, trust center and journal, it publishes machine-readable
  data for agents -- an llms.txt index, an AI index of JSON catalog, sequence, evidence and policy documents, an OpenAPI description
  at /ai/openapi.json, and a read-only public Model Context Protocol endpoint at /mcp.
accessModel:
  pricing: unknown
  onboarding: unknown
  trial: false
  try_now: false
  public: false
  label: Unknown
  confidence: low
  probe_state: covered
  source:
  - authentication
  - security
  generated: '2026-11-06'
  method: derived
image: https://defianceinternational.io/og/high-purity-chemical-sequences-v2.688dc726.png
url: https://artifacts.apis.io/defianceinternational-io/apis.yml
x-type: company
x-source: harvest:mcp-registry
x-tier: profiled
x-tier-reason: enrichment pass 2026-11-05 (modular-v1; was harvest)
specificationVersion: '0.20'
created: '2026-11-05'
modified: '2026-11-05'
tags:
- Company
- Research Chemicals
- Peptides
- Certificate of Analysis
- Laboratory Supplies
- E-Commerce
- MCP
tags_raw:
- Company
- Research Chemicals
- Peptides
- Certificate of Analysis
- Laboratory Supplies
- E-Commerce
- Model Context Protocol
maintainers:
- FN: Kin Lane
  email: kin@apievangelist.com
- FN: APIs.json
  email: info@apis.io
common:
- type: AgenticAccess
  url: agentic-access/defianceinternational-io-agentic-access.yml
- type: RateLimits
  url: rate-limits/defianceinternational-io-rate-limits.yml
- type: Spectral
  url: rules/defianceinternational-io-rules.yml
- type: JSONLD
  url: json-ld/defianceinternational-io-context.jsonld
- type: Vocabulary
  url: vocabulary/defianceinternational-io-vocabulary.yml
- type: AgentSkill
  url: skills/_index.yml
- type: DataModel
  url: data-model/defianceinternational-io-data-model.yml
- type: Conventions
  url: conventions/defianceinternational-io-conventions.yml
- type: Security
  url: security/defianceinternational-io-vulnerability-disclosure.yml
- type: Authentication
  url: authentication/defianceinternational-io-authentication.yml
- type: Lifecycle
  url: lifecycle/defianceinternational-io-lifecycle.yml
- type: ErrorCatalog
  url: errors/defianceinternational-io-problem-types.yml
- type: Conformance
  url: conformance/defianceinternational-io-conformance.yml
- type: Overlay
  url: overlays/defianceinternational-io-openapi-overlay.yaml
- type: LLMsTxt
  url: llms/defianceinternational-io-llms.txt
- type: AgentCard
  url: a2a/defianceinternational-io-a2a.yml
- type: ToolCrosswalk
  url: mcp/defianceinternational-io-tool-crosswalk.yml
- type: MCPServer
  url: mcp/defianceinternational-io-mcp.yml
- type: SecurityTxt
  url: well-known/defianceinternational-io-security.txt
- type: WellKnown
  url: well-known/defianceinternational-io-well-known.yml
- type: Hosts
  url: hosts/defianceinternational-io-hosts.yml
- type: Vendors
  url: vendors/defianceinternational-io-vendors.yml
- type: VulnerabilityDisclosure
  url: security/defianceinternational-io-vulnerability-disclosure.yml
- type: DomainSecurity
  url: security/defianceinternational-io-domain-security.yml
- type: Website
  url: https://defianceinternational.io/
- type: Documentation
  url: https://defianceinternational.io/ai/index.md
- type: LLMsTxt
  url: https://defianceinternational.io/llms.txt
- type: Blog
  url: https://defianceinternational.io/blog
- type: Support
  url: https://defianceinternational.io/support
- type: TrustCenter
  url: https://defianceinternational.io/quality
- type: TermsOfService
  url: https://defianceinternational.io/terms
- type: PrivacyPolicy
  url: https://defianceinternational.io/privacy
apis:
- aid: defianceinternational-io:defianceinternational-io-catalog-api
  name: Defiance International Catalog API
  description: The catalog API from Defiance International — 20 operation(s) for catalog.
  humanURL: https://defianceinternational.io/ai/index.md
  baseURL: https://defianceinternational.io
  tags:
  - Catalog
  tags_raw:
  - catalog
  properties:
  - type: OpenAPI
    url: openapi/defianceinternational-io-catalog-api-openapi.yml
  - type: Documentation
    url: https://defianceinternational.io/ai/index.md
  - type: JSONSchema
    url: json-schema/defianceinternational-io-get-sequence-lot-certificate-200-schema.json
  - type: JSONSchema
    url: json-schema/defianceinternational-io-list-sequence-studies-200-schema.json
  - type: JSONSchema
    url: json-schema/defianceinternational-io-get-evidence-package-200-schema.json
  - type: JSONSchema
    url: json-schema/defianceinternational-io-list-product-studies-v2-200-schema.json
  - type: JSONSchema
    url: json-schema/defianceinternational-io-list-studies-v2-200-schema.json
  - type: JSONSchema
    url: json-schema/defianceinternational-io-list-research-records-200-schema.json
- aid: defianceinternational-io:defianceinternational-io-content-api
  name: Defiance International Content API
  description: The content API from Defiance International — 12 operation(s) for content.
  humanURL: https://defianceinternational.io/ai/index.md
  baseURL: https://defianceinternational.io
  tags:
  - Content
  tags_raw:
  - content
  properties:
  - type: OpenAPI
    url: openapi/defianceinternational-io-content-api-openapi.yml
  - type: Documentation
    url: https://defianceinternational.io/ai/index.md
  - type: JSONSchema
    url: json-schema/defianceinternational-io-get-sequence-lot-certificate-200-schema.json
  - type: JSONSchema
    url: json-schema/defianceinternational-io-list-sequence-studies-200-schema.json
  - type: JSONSchema
    url: json-schema/defianceinternational-io-get-evidence-package-200-schema.json
  - type: JSONSchema
    url: json-schema/defianceinternational-io-list-product-studies-v2-200-schema.json
  - type: JSONSchema
    url: json-schema/defianceinternational-io-list-studies-v2-200-schema.json
  - type: JSONSchema
    url: json-schema/defianceinternational-io-list-research-records-200-schema.json
- aid: defianceinternational-io:defianceinternational-io-documents-api
  name: Defiance International Documents API
  description: The documents API from Defiance International — 22 operation(s) for documents.
  humanURL: https://defianceinternational.io/ai/index.md
  baseURL: https://defianceinternational.io
  tags:
  - Documents
  tags_raw:
  - documents
  properties:
  - type: OpenAPI
    url: openapi/defianceinternational-io-documents-api-openapi.yml
  - type: Documentation
    url: https://defianceinternational.io/ai/index.md
  - type: JSONSchema
    url: json-schema/defianceinternational-io-get-sequence-lot-certificate-200-schema.json
  - type: JSONSchema
    url: json-schema/defianceinternational-io-list-sequence-studies-200-schema.json
  - type: JSONSchema
    url: json-schema/defianceinternational-io-get-evidence-package-200-schema.json
  - type: JSONSchema
    url: json-schema/defianceinternational-io-list-product-studies-v2-200-schema.json
  - type: JSONSchema
    url: json-schema/defianceinternational-io-list-studies-v2-200-schema.json
  - type: JSONSchema
    url: json-schema/defianceinternational-io-list-research-records-200-schema.json
- aid: defianceinternational-io:defianceinternational-io-machine-documents-api
  name: Defiance International Machine Documents API
  description: The machine-documents API from Defiance International — 10 operation(s) for machine-documents.
  humanURL: https://defianceinternational.io/ai/index.md
  baseURL: https://defianceinternational.io
  tags:
  - machine-documents
  properties:
  - type: OpenAPI
    url: openapi/defianceinternational-io-machine-documents-api-openapi.yml
  - type: Documentation
    url: https://defianceinternational.io/ai/index.md
  - type: JSONSchema
    url: json-schema/defianceinternational-io-get-sequence-lot-certificate-200-schema.json
  - type: JSONSchema
    url: json-schema/defianceinternational-io-list-sequence-studies-200-schema.json
  - type: JSONSchema
    url: json-schema/defianceinternational-io-get-evidence-package-200-schema.json
  - type: JSONSchema
    url: json-schema/defianceinternational-io-list-product-studies-v2-200-schema.json
  - type: JSONSchema
    url: json-schema/defianceinternational-io-list-studies-v2-200-schema.json
  - type: JSONSchema
    url: json-schema/defianceinternational-io-list-research-records-200-schema.json
- aid: defianceinternational-io:defianceinternational-io-platform-api
  name: Defiance International Platform API
  description: The platform API from Defiance International — 10 operation(s) for platform.
  humanURL: https://defianceinternational.io/ai/index.md
  baseURL: https://defianceinternational.io
  tags:
  - Platform
  tags_raw:
  - platform
  properties:
  - type: OpenAPI
    url: openapi/defianceinternational-io-platform-api-openapi.yml
  - type: Documentation
    url: https://defianceinternational.io/ai/index.md
  - type: JSONSchema
    url: json-schema/defianceinternational-io-get-sequence-lot-certificate-200-schema.json
  - type: JSONSchema
    url: json-schema/defianceinternational-io-list-sequence-studies-200-schema.json
  - type: JSONSchema
    url: json-schema/defianceinternational-io-get-evidence-package-200-schema.json
  - type: JSONSchema
    url: json-schema/defianceinternational-io-list-product-studies-v2-200-schema.json
  - type: JSONSchema
    url: json-schema/defianceinternational-io-list-studies-v2-200-schema.json
  - type: JSONSchema
    url: json-schema/defianceinternational-io-list-research-records-200-schema.json
- aid: defianceinternational-io:defianceinternational-io-research-register-api
  name: Defiance International Research Register API
  description: The research-register API from Defiance International — 4 operation(s) for research-register.
  humanURL: https://defianceinternational.io/ai/index.md
  baseURL: https://defianceinternational.io
  tags:
  - research-register
  properties:
  - type: OpenAPI
    url: openapi/defianceinternational-io-research-register-api-openapi.yml
  - type: Documentation
    url: https://defianceinternational.io/ai/index.md
  - type: JSONSchema
    url: json-schema/defianceinternational-io-get-sequence-lot-certificate-200-schema.json
  - type: JSONSchema
    url: json-schema/defianceinternational-io-list-sequence-studies-200-schema.json
  - type: JSONSchema
    url: json-schema/defianceinternational-io-get-evidence-package-200-schema.json
  - type: JSONSchema
    url: json-schema/defianceinternational-io-list-product-studies-v2-200-schema.json
  - type: JSONSchema
    url: json-schema/defianceinternational-io-list-studies-v2-200-schema.json
  - type: JSONSchema
    url: json-schema/defianceinternational-io-list-research-records-200-schema.json
- aid: defianceinternational-io:defianceinternational-io-studies-api
  name: Defiance International Studies API
  description: The studies API from Defiance International — 3 operation(s) for studies.
  humanURL: https://defianceinternational.io/ai/index.md
  baseURL: https://defianceinternational.io
  tags:
  - Studies
  tags_raw:
  - studies
  properties:
  - type: OpenAPI
    url: openapi/defianceinternational-io-studies-api-openapi.yml
  - type: Documentation
    url: https://defianceinternational.io/ai/index.md
  - type: JSONSchema
    url: json-schema/defianceinternational-io-get-sequence-lot-certificate-200-schema.json
  - type: JSONSchema
    url: json-schema/defianceinternational-io-list-sequence-studies-200-schema.json
  - type: JSONSchema
    url: json-schema/defianceinternational-io-get-evidence-package-200-schema.json
  - type: JSONSchema
    url: json-schema/defianceinternational-io-list-product-studies-v2-200-schema.json
  - type: JSONSchema
    url: json-schema/defianceinternational-io-list-studies-v2-200-schema.json
  - type: JSONSchema
    url: json-schema/defianceinternational-io-list-research-records-200-schema.json
x-coverage:
  state: covered
  reason: identity-verified
  detail: Website https://defianceinternational.io/ names itself Defiance International (title, masthead); all link pointers
    fetched 200 on 2026-11-05 with a browser UA.
  evidence:
  - url: https://defianceinternational.io/
    status: 200
  - url: https://defianceinternational.io/about
    status: 200
  - url: https://defianceinternational.io/llms.txt
    status: 200
  - url: https://defianceinternational.io/ai/index.md
    status: 200
  - url: https://defianceinternational.io/blog
    status: 200
  - url: https://defianceinternational.io/support
    status: 200
  - url: https://defianceinternational.io/quality
    status: 200
  - url: https://defianceinternational.io/terms
    status: 200
  - url: https://defianceinternational.io/privacy
    status: 200
x-enrichment:
  date: '2026-11-05'
  status: enriched
  artifacts_added: 44
  pass: modular-v1
  engine: identity=anthropic,contract=anthropic,surfaces=anthropic,docs=anthropic,regulatory=anthropic

Defiance International API — frequently asked questions

Does Defiance International have an API?

Yes. APIs.io lists 7 APIs from Defiance International, including Defiance International Catalog API, Defiance International Content API and Defiance International Documents API, and 4 more.

Is there an OpenAPI specification for the Defiance International API?

Yes. APIs.io indexes 7 OpenAPI specifications for Defiance International, each linked for download from this page.

How do I authenticate with the Defiance International API?

Defiance International uses bearer-token authentication (1 scheme). The details are profiled on APIs.io as Defianceinternational Io Authentication.

Does Defiance International have an MCP server?

Yes. APIs.io lists 1 MCP server for Defiance International: Remote MCP server at defianceinternational.io; 5 tools listed.

Is the Defiance International API ready for AI agents?

Defiance International has a Kin Score of 40.7 out of 100 (developing) and an Agent Readiness score of 35.7 (agent-ready), scored by API Evangelist on 2026-11-06.

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