Centrexion Therapeutics

Centrexion Therapeutics is a late clinical-stage biopharmaceutical company headquartered at One Boston Place, Suite 3520, Boston, Massachusetts, developing novel non-opioid, non-addictive therapies for chronic pain alongside an emerging portfolio in immunology and inflammation. The company was founded by Sol Barer, Ph.D. — a founder of Celgene, who chairs the board — and by James N. Campbell, M.D., president and chief scientific officer and Professor Emeritus of neurosurgery at Johns Hopkins University School of Medicine. Jeffrey B. Kindler, formerly chief executive of Pfizer, joined as chief executive officer in 2013. Its lead asset, CNTX-4975, is a highly purified synthetic trans-capsaicin injected directly into the painful joint that produces analgesia by reversibly deactivating the end terminals of TRPV1-expressing primary afferent pain fibers, delivering pain relief that can last months while clearing the body within 24 hours; the FDA granted it Fast Track designation for moderate-to-severe osteoarthritis knee pain. Centrexion runs no developer program and publishes no product API, developer portal, API documentation, SDK or status page. The only machine-readable surface reachable without credentials is the WordPress REST content API behind centrexion.com, catalogued here, together with an llms.txt the site generates for AI crawlers.

Centrexion Therapeutics publishes 1 API on the APIs.io network. Tagged areas include Company, Biopharmaceutical, Pharmaceuticals, Chronic Pain, and non-opioid-analgesics.

Centrexion Therapeutics’ developer surface includes authentication and 20 more developer resources.

🌐 Visit website 📡 Source on GitHub

17.0/100 emerging ▬ flat Agent 4/100 human only Front door AI 1/6 silent saas Full breakdown ↓
scored 2026-09-25 · rubric v0.23.0

1 APIs

Company Biopharmaceutical Pharmaceuticals Chronic Painnon-opioid-analgesicsImmunology inflammation Clinical Trials Life Sciences content-api

Kin Score

Kin Score How this is scored →
scored 2026-09-25 · rubric v0.23.0

Composite quality — 17.0/100 · emerging

Contract Quality 0.0 / 21

Developer Ergonomics 3.9 / 17

Access Clarity 3.6 / 17

Operational Transparency 0.0 / 11

Contract Governance 0.5 / 10

Discoverability 5.5 / 9

Regulatory Posture 2.9 / 15

Agent readiness — 4/100 · human only

Machine-Readable Contract 0 / 18

Agentic Access Contract 0 / 10

Documented Reversibility 0 / 6

MCP Server 0 / 12

Machine-Readable Auth 10 / 10

Idempotency 0 / 9

Stable Error Semantics 8 / 8

Request/Response Examples 0 / 7

Rate-Limit Signaling 0 / 7

Typed Event Surface 0 / 6

Agent Skills 5 / 5

Well-Known Catalog 0 / 4

Consent & Bot Identity 0 / 3

A2A Agent Card 0 / 8

Dry-Run / Simulate Mode 0 / 4

Delegated User Identity 0 / 6

Protected Resource Metadata 0 / 5

Registration Without a Human 0 / 6

Agentic Commerce Well-Known Document 0 / 5

Regulatory Posture applies to this provider. Its tags matched the Health regime, so Regulatory Posture carries 15 points of the composite. If this regime is wrong for your business, say so on your provider repo — the applicability map is public and we will correct it.

Create-or-Update Ergonomics does not apply to this provider. The published contracts declare no write operations, and a read-only API cannot create-or-update. The facet is excluded from this provider's denominator entirely — not scored zero. A reference or data API is not deficient for being unable to upsert.

The six quality facets above are damped to 85 points between them, because the conditional facet above carries the other 15. That is why each facet's contribution is shown against a damped maximum: raising a quality facet moves the composite by 85% of its nominal weight, not 100%. The full arithmetic is at apis.io/rating/.

Improve this rating by publishing the missing artifacts — every area above can be raised, and the full rubric is at apis.io/rating/. Every facet and dimension name above is a link: it opens that measurement's own page — what it means, the exact checks that feed it, how the whole catalog distributes on it, and the providers at the top of it. This rating is computed from github.com/api-evangelist/centrexion-therapeutics: open an issue to ask a question, or submit a pull request to add artifacts. Submit an artifact on GitHub — free → Manage your own listing — the Influence plan, $499/mo →

APIs 1

Individual APIs this provider publishes, each with its own machine-readable definition.

Centrexion Therapeutics Website (WordPress REST)

The public WordPress REST API (wp-json) of the Centrexion Therapeutics website at centrexion.com: the route index of the site's content management system, catalogued as one site...

Open Collections 1

Open, tool-agnostic API collections (OpenAPI-derived and Bruno).

API Collection

OPEN COLLECTION

Security Posture 2

Authentication, domain security, vulnerability disclosure, and trust-center signals.

Centrexion Therapeutics Authentication

1 scheme

SECURITY

Centrexion Therapeutics Domain Security

TLSv1.3

SECURITY

Resources

Agent Surfaces 3

MCP servers, agent skills, and machine-readable catalogs

WellKnown

WellKnown

LLMsTxt

LLMsTxt

AgentSkill

AgentSkill

Design & Contract 5

Pagination, idempotency, versioning, errors, and events

Conventions

Conformance

ErrorCatalog

Lifecycle

DataModel

Access & Security 2

Authentication, authorization, and security posture

Authentication

Authentication

DomainSecurity

DomainSecurity

Operate 1

Status, limits, changes, and where to get help

Contact

Contact

Commercial 2

Pricing, plans, and the legal terms of use

PrivacyPolicy

PrivacyPolicy

TermsOfService

TermsOfService

Company 4

The organization behind the API

Website

Website

BlogRSS

BlogRSS

LinkedIn

Twitter

Twitter

Other 4

Properties that don't map to a standard resource type

Overlay

Pipeline

Leadership

SecondaryMarket

Source (apis.yml)

aid: centrexion-therapeutics
name: Centrexion Therapeutics
description: Centrexion Therapeutics is a late clinical-stage biopharmaceutical company headquartered at One Boston Place,
  Suite 3520, Boston, Massachusetts, developing novel non-opioid, non-addictive therapies for chronic pain alongside an emerging
  portfolio in immunology and inflammation. The company was founded by Sol Barer, Ph.D. — a founder of Celgene, who chairs
  the board — and by James N. Campbell, M.D., president and chief scientific officer and Professor Emeritus of neurosurgery
  at Johns Hopkins University School of Medicine. Jeffrey B. Kindler, formerly chief executive of Pfizer, joined as chief
  executive officer in 2013. Its lead asset, CNTX-4975, is a highly purified synthetic trans-capsaicin injected directly into
  the painful joint that produces analgesia by reversibly deactivating the end terminals of TRPV1-expressing primary afferent
  pain fibers, delivering pain relief that can last months while clearing the body within 24 hours; the FDA granted it Fast
  Track designation for moderate-to-severe osteoarthritis knee pain. Centrexion runs no developer program and publishes no
  product API, developer portal, API documentation, SDK or status page. The only machine-readable surface reachable without
  credentials is the WordPress REST content API behind centrexion.com, catalogued here, together with an llms.txt the site
  generates for AI crawlers.
deliveryModel:
  model: saas
  open_source: false
  commercial: true
  callable_host: true
  label: Hosted service · you call their endpoint
  confidence: high
  source:
  - openapi
  - pricing
  generated: '2026-08-28'
  method: derived
accessModel:
  pricing: unknown
  onboarding: unknown
  trial: false
  try_now: false
  public: false
  label: Unknown
  confidence: low
  source:
  - authentication
  - security
  generated: '2026-09-03'
  method: derived
image: https://centrexion.com/wp-content/uploads/2025/08/Centrexion_LOGO_275px.png
url: https://raw.githubusercontent.com/api-evangelist/centrexion-therapeutics/refs/heads/main/apis.yml
x-type: company
x-source: harvest:secondary-market
x-tier: profiled
x-tier-reason: enriched
specificationVersion: '0.23'
created: '2026-08-09'
modified: '2026-08-09'
tags:
- Company
- Biopharmaceutical
- Pharmaceuticals
- Chronic Pain
- non-opioid-analgesics
- Immunology
- inflammation
- Clinical Trials
- Life Sciences
- content-api
tags_raw:
- Company
- biopharmaceutical
- pharmaceuticals
- chronic-pain
- non-opioid-analgesics
- immunology
- inflammation
- clinical-trials
- life-sciences
- content-api
apis:
- aid: centrexion-therapeutics:centrexion-com-website-wordpress-rest
  name: Centrexion Therapeutics Website (WordPress REST)
  description: 'The public WordPress REST API (wp-json) of the Centrexion Therapeutics website at centrexion.com: the route
    index of the site''s content management system, catalogued as one site surface rather than as separate APIs.'
  baseURL: https://centrexion.com/wp-json
  tags:
  - WordPress
  x-surface: platform-generated
  properties:
  - type: Documentation
    url: https://centrexion.com/wp-json
  x-platform: wordpress
  x-platform-surface: rest
maintainers:
- FN: Kin Lane
  email: kin@apievangelist.com
- FN: APIs.json
  email: info@apis.io
common:
- type: Overlay
  url: overlays/centrexion-therapeutics-content-overlay.yaml
- type: Website
  url: https://centrexion.com/
- type: Pipeline
  url: https://centrexion.com/pipeline/
- type: Leadership
  url: https://centrexion.com/team/
- type: Contact
  url: https://centrexion.com/contact/
- type: BlogRSS
  url: https://centrexion.com/feed/
- type: PrivacyPolicy
  url: https://centrexion.com/privacy-policy/
- type: TermsOfService
  url: https://centrexion.com/terms-of-use/
- type: LinkedIn
  url: https://www.linkedin.com/company/10487363
- type: Twitter
  url: https://x.com/CentrexionTX
- type: SecondaryMarket
  url: https://forgeglobal.com/centrexion-therapeutics_stock/
- type: Authentication
  url: authentication/centrexion-therapeutics-authentication.yml
- type: Conventions
  url: conventions/centrexion-therapeutics-conventions.yml
- type: Conformance
  url: conformance/centrexion-therapeutics-conformance.yml
- type: ErrorCatalog
  url: errors/centrexion-therapeutics-problem-types.yml
- type: Lifecycle
  url: lifecycle/centrexion-therapeutics-lifecycle.yml
- type: DataModel
  url: data-model/centrexion-therapeutics-data-model.yml
- type: WellKnown
  url: well-known/centrexion-therapeutics-well-known.yml
- type: DomainSecurity
  url: security/centrexion-therapeutics-domain-security.yml
- type: LLMsTxt
  url: llms/centrexion-therapeutics-llms.txt
- type: AgentSkill
  url: skills/_index.yml
x-enrichment:
  date: '2026-08-09'
  status: enriched
  artifacts_added: 15
  pass: local-v1

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