Amber Bio

Amber Bio is a San Francisco biotechnology company developing an RNA-based gene-editing platform capable of making multi-kilobase edits — rewriting thousands of bases on a single RNA strand in one step — to reach previously undruggable patient populations. Because edited RNA eventually degrades in the body, the approach is designed to be safer and reversible compared with permanent DNA editing. The platform pairs multi-kilobase RNA writing with AI foundation models to target diverse pathogenic variants across patients with a single product, initially focused on ophthalmology and central nervous system diseases. Founded by CRISPR-field researchers from the Broad Institute and UC Berkeley (co-founder and CTO Basem Al-Shayeb, advised by Nobel Laureate Jennifer Doudna), Amber Bio launched in 2023 with a $26M seed round co-led by Playground Global and Andreessen Horowitz. It has no public developer API; this API Evangelist profile tracks the company as a portfolio lead.

Amber Bio is profiled on the APIs.io network. Tagged areas include Company, Engineered Biology, RNA Editing, Gene Editing, and Genetic Medicine.

Amber Bio’s developer surface includes product news and 4 more developer resources.

🌐 Visit website 📡 Source on GitHub

5.0/100 minimal ▬ flat Agent 0/100 human only Full breakdown ↓
scored 2026-09-08 · rubric v0.20.0

0 APIs

Company Engineered Biology RNA Editing Gene Editing Genetic Medicine Biotechnology CRISPR Therapeutics

Kin Score

Kin Score How this is scored →
scored 2026-09-08 · rubric v0.20.0

Composite quality — 5.0/100 · minimal

Contract Quality 0.0 / 25

Developer Ergonomics 0.0 / 20

Access Clarity 0.0 / 20

Operational Transparency 0.0 / 13

Contract Governance 0.0 / 12

Discoverability 5.0 / 10

Agent readiness — 0/100 · human only

Machine-Readable Contract 0 / 18

Agentic Access Contract 0 / 10

Documented Reversibility 0 / 6

MCP Server 0 / 12

Machine-Readable Auth 0 / 10

Idempotency 0 / 9

Stable Error Semantics 0 / 8

Request/Response Examples 0 / 7

Rate-Limit Signaling 0 / 7

Typed Event Surface 0 / 6

Agent Skills 0 / 5

Well-Known Catalog 0 / 4

Consent & Bot Identity 0 / 3

A2A Agent Card 0 / 8

Dry-Run / Simulate Mode 0 / 4

Delegated User Identity 0 / 6

Protected Resource Metadata 0 / 5

Registration Without a Human 0 / 6

Agentic Commerce Well-Known Document 0 / 5

Create-or-Update Ergonomics could not be measured. We hold no machine-readable contract for this provider to read, so there is nothing to measure a write surface against. Excluded rather than scored zero: never-measured and measured-empty are different facts. Publishing an OpenAPI is what makes this facet — and several others — scorable at all.

Improve this rating by publishing the missing artifacts — every area above can be raised, and the full rubric is at apis.io/rating/. Every facet and dimension name above is a link: it opens that measurement's own page — what it means, the exact checks that feed it, how the whole catalog distributes on it, and the providers at the top of it. This rating is computed from github.com/api-evangelist/amber-bio: open an issue to ask a question, or submit a pull request to add artifacts. Submit an artifact on GitHub — free → Manage your own listing — the Influence plan, $499/mo →

Security Posture 1

Authentication, domain security, vulnerability disclosure, and trust-center signals.

Amber Bio Domain Security

TLSv1.3 · HSTS · DMARC

SECURITY

Resources

Access & Security 1

Authentication, authorization, and security posture

DomainSecurity

DomainSecurity

Company 3

The organization behind the API

Website

Website

Careers

Careers

News

News

Other 1

Properties that don't map to a standard resource type

Team

Team

Source (apis.yml)

aid: amber-bio
name: Amber Bio
description: Amber Bio is a San Francisco biotechnology company developing an RNA-based gene-editing platform capable of making
  multi-kilobase edits — rewriting thousands of bases on a single RNA strand in one step — to reach previously undruggable
  patient populations. Because edited RNA eventually degrades in the body, the approach is designed to be safer and reversible
  compared with permanent DNA editing. The platform pairs multi-kilobase RNA writing with AI foundation models to target diverse
  pathogenic variants across patients with a single product, initially focused on ophthalmology and central nervous system
  diseases. Founded by CRISPR-field researchers from the Broad Institute and UC Berkeley (co-founder and CTO Basem Al-Shayeb,
  advised by Nobel Laureate Jennifer Doudna), Amber Bio launched in 2023 with a $26M seed round co-led by Playground Global
  and Andreessen Horowitz. It has no public developer API; this API Evangelist profile tracks the company as a portfolio lead.
url: https://raw.githubusercontent.com/api-evangelist/amber-bio/refs/heads/main/apis.yml
x-type: company
x-source: vc-portfolio
x-backed-by:
- playground-global
x-tier: stub
x-tier-reason: portfolio-lead
deliveryModel:
  model: unknown
  open_source: false
  commercial: false
  callable_host: false
  label: Delivery model not determined — needs a product licence on record
  confidence: low
  source:
  - none
  generated: '2026-08-28'
  method: derived
accessModel:
  pricing: unknown
  onboarding: unknown
  trial: false
  try_now: false
  public: false
  label: Unknown
  confidence: low
  source: []
  generated: '2026-07-22'
  method: derived
specificationVersion: '0.23'
created: '2026-07-17'
modified: '2026-07-17'
image: https://cdn.prod.website-files.com/6245f65e49aca16254e8bad8/624dc97fcb2b8c6590085e6f_OPG.png
tags:
- Company
- Engineered Biology
- RNA Editing
- Gene Editing
- Genetic Medicine
- Biotechnology
- CRISPR
- Therapeutics
apis: []
maintainers:
- FN: Kin Lane
  email: kin@apievangelist.com
- FN: APIs.json
  email: info@apis.io
common:
- type: DomainSecurity
  url: security/amber-bio-domain-security.yml
- type: Website
  url: https://www.amber.bio/
- type: Careers
  url: https://www.amber.bio/careers
- type: News
  url: https://www.amber.bio/#news
- type: Team
  url: https://www.amber.bio/#team
x-enrichment:
  date: '2026-07-19'
  status: backfilled
  pass: local-v1
  note: backfilled from .gitignore signal + verified work evidence

Work with this as data

Every provider here is available over the APIs.io API and to AI agents over MCP.

MCP server

One button, every client — Claude, Cursor, VS Code and the rest.

https://apis.io/mcp

Tools for providers

9 MCP tools reach this

find_providersBrowse and filter every provider in the catalog.
get_provider_artifactsEvery artifact this provider publishes, grouped by type.
get_provider_operationsEvery operation across all of their OpenAPIs — one call instead of parsing every spec.
get_provider_toolsEvery MCP tool they ship, with the operation each wraps.
get_provider_evidenceHow each part of their score was established. Free — the basis for a claim should not sit behind it.
get_provider_ratingPRO — composite, band, trend and facet scores.
apis_io_searchSTART HERE — APIs, providers and tags for one query, each with its total.
resolveTurn a domain, URL or GitHub org into the provider it belongs to.
find_cohortsEvery scored population of providers in the catalog.

All 92 tools →

Call it yourself

curl for this page

This provider

curl "https://apis.io/api/v1/providers/amber-bio"

All providers

curl "https://apis.io/api/v1/providers?limit=25"

Every operation they expose

curl "https://apis.io/api/v1/providers/amber-bio/operations?limit=25"

How their score was established

curl "https://apis.io/api/v1/providers/amber-bio/evidence"

Discovery needs no key. Ratings and market analysis are Pro.

Get an API key

Free tier, no form to fill in. Signing in shares your email address with us — we store it to create your key and to recognise you if you sign in with another provider. See our Privacy Policy and Terms.

GitHub Google LinkedIn

A second provider on the same verified email joins the account you already have.