AcuraStem

AcuraStem, Inc. is a privately held, patient-based biotechnology company headquartered in Monrovia, California, developing therapeutics for neurodegenerative diseases including sporadic ALS (amyotrophic lateral sclerosis) and frontotemporal dementia (FTD). The company's proprietary iNeuroRx drug-discovery platform builds disease models from induced pluripotent stem cells (iPSC) taken from individual patients, in place of animal models, and pairs them with machine-learning analysis to identify and validate targets. Its lead antisense oligonucleotide candidate, AS-241 (PIKFYVE), is advancing toward first-in-human testing with California Institute for Regenerative Medicine (CIRM) grant support. AcuraStem is a therapeutics developer rather than a software vendor: it publishes no public API, developer portal, SDK, or machine-readable contract of any kind. This profile records that absence with the probe evidence behind it.

AcuraStem is profiled on the APIs.io network. Tagged areas include Company, Biotechnology, Therapeutics, Life Sciences, and Drug Discovery.

AcuraStem’s developer surface includes engineering blog and 10 more developer resources.

🌐 Visit website 📡 Profile data on GitHub

7.5/100 minimal ▬ flat Agent 0/100 human only Front door AI 1/6 silent Heartbeat 100/100 alive Full breakdown ↓
scored 2026-11-06 · rubric v0.27.0 · Show this score on your site →

0 APIs

Company Biotechnology Therapeutics Life Sciences Drug Discovery Neuroscience Neurodegenerative Disease ALS Stem Cells Machine Learning Private Company

Kin Score

Kin Score How this is scored →
scored 2026-11-06 · rubric v0.27.0

Composite quality — 7.5/100 · minimal

Contract Quality 0.0 / 21

Developer Ergonomics 0.4 / 17

Access Clarity 1.8 / 17

Operational Transparency 0.0 / 11

Contract Governance 0.0 / 10

Discoverability 4.8 / 9

Regulatory Posture 1.1 / 15

Agent readiness — 0/100 · human only

Machine-Readable Contract 0 / 18

Agentic Access Contract 0 / 10

Documented Reversibility 0 / 6

MCP Server 0 / 12

Machine-Readable Auth 0 / 10

Idempotency 0 / 9

Stable Error Semantics 0 / 8

Request/Response Examples 0 / 7

Rate-Limit Signaling 0 / 7

Typed Event Surface 0 / 6

Agent Skills 0 / 5

Well-Known Catalog 0 / 4

Consent & Bot Identity 0 / 3

A2A Agent Card 0 / 8

Dry-Run / Simulate Mode 0 / 4

Delegated User Identity 0 / 6

Protected Resource Metadata 0 / 5

Registration Without a Human 0 / 6

Agentic Commerce Well-Known Document 0 / 5

Pagination 5 / 5

Distinct Operations 3 / 3

MCP Tool Quality 6 / 6

Regulatory Posture applies to this provider. Its tags matched the Health regime, so Regulatory Posture carries 15 points of the composite. If this regime is wrong for your business, say so on your provider repo — the applicability map is public and we will correct it.

Create-or-Update Ergonomics could not be measured. We hold no machine-readable contract for this provider to read, so there is nothing to measure a write surface against. Excluded rather than scored zero: never-measured and measured-empty are different facts. Publishing an OpenAPI is what makes this facet — and several others — scorable at all.

The six quality facets above are damped to 85 points between them, because the conditional facet above carries the other 15. That is why each facet's contribution is shown against a damped maximum: raising a quality facet moves the composite by 85% of its nominal weight, not 100%. The full arithmetic is at apis.io/rating/.

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Agent readiness — checks not met, largest first (exact, from this profile):

Machine-Readable Contract +18 pts — api_specs includes an OpenAPI document
MCP Server +12 pts — deployment.mode + probe verdict on the mcp/ manifest, not the pointer; an unprobed slug falls back to authorship
Agentic Access Contract +10 pts — agentic_access artifact present (x-agentic-access), graded by author
Machine-Readable Auth +10 pts — a served openid-configuration/oauth-authorization-server carrying `issuer` (served), else the securitySchemes class in the provider OpenAPIs — bound (mutualTLS, DPoP, Signature) > negotiable (oauth2 authorizationCode/clientCredentials, openIdConnect) > bearer (http bearer, apiKey)
Idempotency +9 pts — OpenAPI mutating operations declare an idempotency key — a header, a request-body property, or a named de-duplication token whose own description says so (verified); else common[].type matches /idempoten/i (documented)
Stable Error Semantics +8 pts — OpenAPI $refs a shared error schema across 4xx/5xx responses (verified), else common[].type includes ErrorCatalog / ErrorCodes / DeclineCodes

13 more unmet checks in the Agent Readiness table above.

Kin Score — facets with the most composite points still available (weight × headroom):

Contract Quality scores 0.0 — up to +25.0 composite points
Developer Ergonomics scores 2.4 — up to +19.5 composite points
Access Clarity scores 10.5 — up to +17.9 composite points

Each check links to what satisfies it. Publish the artifact, or tell us where it already lives, and the score moves on the next scoring run.

Improve this rating by publishing the missing artifacts — every area above can be raised, and the full rubric is at apis.io/rating/. Every facet and dimension name above is a link: it opens that measurement's own page — what it means, the exact checks that feed it, how the whole catalog distributes on it, and the providers at the top of it. This rating is computed from the provider profile at artifacts.apis.io/acurastem/apis.yml: open an issue on github.com/api-evangelist/acurastem to ask a question or point us at an artifact you publish. Submit an artifact on GitHub — free → Manage your own listing — the Influence plan, $499/mo →

Security Posture 1

Authentication, domain security, vulnerability disclosure, and trust-center signals.

Acurastem Domain Security

TLSv1.3 · DMARC

SECURITY

Resources

Agent Surfaces 1

MCP servers, agent skills, and machine-readable catalogs

LLMsTxt

LLMsTxt

Access & Security 1

Authentication, authorization, and security posture

DomainSecurity

DomainSecurity

Commercial 1

Pricing, plans, and the legal terms of use

PrivacyPolicy

PrivacyPolicy

Company 7

The organization behind the API

BlogRSS

Website

About

Blog

Newsroom

Careers

LinkedIn

Scroll for all 7

Other 1

Properties that don't map to a standard resource type

Source (apis.yml)

aid: acurastem
name: AcuraStem
description: 'AcuraStem, Inc. is a privately held, patient-based biotechnology company headquartered in Monrovia, California,
  developing therapeutics for neurodegenerative diseases including sporadic ALS (amyotrophic lateral sclerosis) and frontotemporal
  dementia (FTD). The company''s proprietary iNeuroRx drug-discovery platform builds disease models from induced pluripotent
  stem cells (iPSC) taken from individual patients, in place of animal models, and pairs them with machine-learning analysis
  to identify and validate targets. Its lead antisense oligonucleotide candidate, AS-241 (PIKFYVE), is advancing toward first-in-human
  testing with California Institute for Regenerative Medicine (CIRM) grant support. AcuraStem is a therapeutics developer
  rather than a software vendor: it publishes no public API, developer portal, SDK, or machine-readable contract of any kind.
  This profile records that absence with the probe evidence behind it.'
url: https://raw.githubusercontent.com/api-evangelist/acurastem/refs/heads/main/apis.yml
accessModel:
  pricing: unknown
  onboarding: unknown
  trial: false
  try_now: false
  public: false
  label: Unknown
  confidence: low
  probe_state: none
  source:
  - security
  generated: '2026-11-06'
  method: derived
image: https://acurastem.com/application/files/7516/7235/4056/acs_logo_notag.png
x-type: company
x-source: harvest:secondary-market
x-tier: stub
x-tier-reason: harvest
specificationVersion: '0.20'
created: '2026-09-06'
modified: '2026-10-06'
tags:
- Company
- Biotechnology
- Therapeutics
- Life Sciences
- Drug Discovery
- Neuroscience
- Neurodegenerative Disease
- ALS
- Stem Cells
- Machine Learning
- Private Company
tags_raw:
- Company
- Biotechnology
- Therapeutics
- Life Sciences
- Drug Discovery
- Neuroscience
- Neurodegenerative Disease
- ALS
- Stem Cells
- Machine Learning
- Private Company
- Machine-Learning
apis: []
maintainers:
- FN: Kin Lane
  email: kin@apievangelist.com
- FN: APIs.json
  email: info@apis.io
common:
- url: https://acurastem.com/rss/blog
  type: BlogRSS
- type: DomainSecurity
  url: security/acurastem-domain-security.yml
- type: LLMsTxt
  url: llms/acurastem-llms.txt
- type: Website
  url: https://acurastem.com/
- type: About
  url: https://acurastem.com/about-us
- type: Blog
  url: https://acurastem.com/blog
- type: Newsroom
  url: https://acurastem.com/media
- type: Careers
  url: https://acurastem.com/careers
- type: PrivacyPolicy
  url: https://acurastem.com/privacy-policy
- type: LinkedIn
  url: https://www.linkedin.com/company/12903559/
- type: X
  url: https://x.com/acurastem
x-enrichment:
  date: '2026-09-06'
  status: minimal
  artifacts_added: 3
  pass: local-v3
x-coverage:
  state: none
  reason: not-a-software-company
  detail: AcuraStem is a preclinical ALS/FTD therapeutics developer whose entire public web presence is a six-page Concrete
    CMS 9.5.2 marketing site (about, science, therapeutics, media, careers) with no developer, API, or data-access section,
    no API subdomain resolving in DNS, and an empty GitHub organization with zero public repositories.
  evidence:
  - url: https://acurastem.com/
    status: 200
  - url: https://acurastem.com/openapi.json
    status: 404
  - url: https://acurastem.com/.well-known/api-catalog
    status: 404
  - url: https://acurastem.com/llms.txt
    status: 404
  - url: https://acurastem.com/sitemap.xml
    status: 200
  - url: https://api.github.com/orgs/acurastem
    status: 200
  checked: '2026-09-06'

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