ivive.app

IVIVE.app provides a free in‑vitro to hepatic clearance calculator for drug discovery, offering batch calculations, species scaling, structure‑based predictions, and an MCP server for LLM integration. It features a web UI, REST API, and open‑source tools for scientists to predict clearance without an account.

ivive.app publishes 11 API contracts indexed on the APIs.io network, including Auth API, Correction Equations API, Health API, and 8 more. Tagged areas include Company, IVIVE, Drug Discovery, HepaticClearance, and Open Source.

The ivive.app catalog on APIs.io includes 1 JSON-LD context and 1 Spectral governance ruleset.

ivive.app’s developer surface includes authentication, documentation, API reference, getting-started guide, support, and 15 more developer resources.

🌐 Visit website 📡 Profile data on GitHub

38.4/100 thin Agent 28/100 agent aware Full breakdown ↓
scored 2026-11-13 · rubric v0.28.0 · Show this score on your site →

1 published contract 1 MCP Servers 2 Agent Skills

CompanyIVIVEDrug DiscoveryHepaticClearanceOpen Source

Kin Score

Kin Score How this is scored →
scored 2026-11-13 · rubric v0.28.0

Composite quality — 38.4/100 · thin

Contract Quality 12.3 / 21

Developer Ergonomics 8.0 / 17

Access Clarity 2.9 / 17

Operational Transparency 0.0 / 11

Contract Governance 2.2 / 10

Discoverability 5.5 / 9

Regulatory Posture 4.3 / 15

Agent readiness — 28/100 · agent aware

Machine-Readable Contract 18 / 18

Agentic Access Contract 10 / 10

Documented Reversibility 0 / 6

MCP Server 12 / 12

Machine-Readable Auth 10 / 10

Idempotency 0 / 9

Stable Error Semantics 8 / 8

Request/Response Examples 0 / 7

Rate-Limit Signaling 0 / 7

Typed Event Surface 0 / 6

Agent Skills 5 / 5

Well-Known Catalog 0 / 4

Consent & Bot Identity 0 / 3

A2A Agent Card 0 / 8

Dry-Run / Simulate Mode 0 / 4

Delegated User Identity 0 / 6

Protected Resource Metadata 0 / 5

Registration Without a Human 0 / 6

Agentic Commerce Well-Known Document 0 / 5

Pagination 0 / 5

Distinct Operations 3 / 3

MCP Tool Quality 6 / 6

Regulatory Posture applies to this provider. Its tags matched the Horizontal (data, software, accessibility, platform) regime, so Regulatory Posture carries 15 points of the composite. If this regime is wrong for your business, say so on your provider repo — the applicability map is public and we will correct it.

Create-or-Update Ergonomics could not be measured. We hold no machine-readable contract for this provider to read, so there is nothing to measure a write surface against. Excluded rather than scored zero: never-measured and measured-empty are different facts. Publishing an OpenAPI is what makes this facet — and several others — scorable at all.

The six quality facets above are damped to 85 points between them, because the conditional facet above carries the other 15. That is why each facet's contribution is shown against a damped maximum: raising a quality facet moves the composite by 85% of its nominal weight, not 100%. The full arithmetic is at apis.io/rating/.

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Agent readiness — checks not met, largest first (exact, from this profile):

Idempotency +9 pts — OpenAPI mutating operations declare an idempotency key — a header, a request-body property, or a named de-duplication token whose own description says so (verified); else common[].type matches /idempoten/i (documented) Ask about this →
A2A Agent Card +8 pts — a2a/-a2a.yml manifest, graded on conformance.grade against A2A 1.0.0 Ask about this →
Rate-Limit Signaling +7 pts — OpenAPI responses document X-RateLimit-* / RateLimit headers (verified), else a rate_limits artifact or RateLimits link (documented) Ask about this →
Request/Response Examples +7 pts — share of operations carrying request/response examples; else an Examples / Code Samples link Ask about this →
Registration Without a Human +6 pts — a `registration_endpoint` in the served RFC 8414 / OIDC discovery document Ask about this →
Delegated User Identity +6 pts — a served discovery document listing authorization_code in grant_types_supported (served), else an oauth2 authorizationCode flow or openIdConnect declared in an OpenAPI (documented) Ask about this →

8 more unmet checks in the Agent Readiness table above.

Kin Score — facets with the most composite points still available (weight × headroom):

Access Clarity scores 17.0 — up to +16.6 composite points Ask about this →
Operational Transparency scores 0.0 — up to +13.0 composite points Ask about this →
Developer Ergonomics scores 47.0 — up to +10.6 composite points Ask about this →

Each check links to what satisfies it. Publish the artifact, or tell us where it already lives, and the score moves on the next scoring run.

Not sure how this applies to your stack? Ask about any one item. Kin Lane reads every question, looks at your profile and your situation, and replies with what a fix would take — scoped to that one area, priced up front, yours whether you ship it or not. Ask a question →

Improve this rating by publishing the missing artifacts — every area above can be raised, and the full rubric is at apis.io/rating/. Every facet and dimension name above is a link: it opens that measurement's own page — what it means, the exact checks that feed it, how the whole catalog distributes on it, and the providers at the top of it. This rating is computed from the provider profile at artifacts.apis.io/ivive-app/apis.yml: open an issue on github.com/api-evangelist/ivive-app to ask a question or point us at an artifact you publish. Submit an artifact on GitHub — free → Manage your own listing — the Influence plan, $499/mo →

Standards implemented 2

Standards this provider implements or carries. De facto ones are profiled and measured by the API Commons; formal ones come from the standards directory and are linked by the provider's own tags. The evidence column says how each claim was established — not that it was made.

Model Context Protocol (MCP)

measured — observed by APIs.io (documented)

OpenAPI

measured — observed by APIs.io (published)

APIs 11

Individual APIs this provider publishes, each with its own machine-readable definition.

ivive.app Auth API

The auth API from ivive.app — 5 operation(s) for auth.

ivive.app Correction Equations API

The correction-equations API from ivive.app — 3 operation(s) for correction-equations.

ivive.app Health API

The health API from ivive.app — 1 operation(s) for health.

ivive.app Ivivc API

The ivivc API from ivive.app — 6 operation(s) for ivivc.

ivive.app Ivive API

The ivive API from ivive.app — 4 operation(s) for ivive.

ivive.app Library API

The library API from ivive.app — 2 operation(s) for library.

ivive.app Molecule API

The molecule API from ivive.app — 2 operation(s) for molecule.

ivive.app Pk API

The pk API from ivive.app — 1 operation(s) for pk.

ivive.app Prediction API

The prediction API from ivive.app — 5 operation(s) for prediction.

ivive.app Reference Compounds API

The reference-compounds API from ivive.app — 1 operation(s) for reference-compounds.

ivive.app Scaling API

The scaling API from ivive.app — 1 operation(s) for scaling.

Scroll for all 11

MCP Servers 1

Model Context Protocol servers that expose these APIs to AI agents.

ivive.app MCP Server

Remote MCP server at api.ivive.app.

MCP SERVER

Agent Skills 2

Packaged agent skills for driving this provider's APIs from an AI assistant.

ivive-app-ivivc-fit-and-predict

AGENT SKILL

ivive-app-library-prepare-and-analogues

AGENT SKILL

Semantic Vocabularies 1

JSON-LD contexts and semantic vocabularies used across these APIs.

Ivive App Context

92 classes · 204 properties

JSON-LD

Spectral Rules 1

Spectral governance rulesets for linting and validating these APIs. Counts are the severity each rule declares, not results of running them.

ivive.app API Rules

54 rules · 43 error-severity 6 warn-severity 5 info-severity

SPECTRAL

JSON Schema 6

Standalone JSON Schema definitions for this provider's data models.

CLhepRequest

9 properties

JSON SCHEMA

CLhepResponse

14 properties

JSON SCHEMA

FitResponse

22 properties

JSON SCHEMA

ModelDetail

22 properties

JSON SCHEMA

PredictionResponse

8 properties

JSON SCHEMA

SensitivityRequest

12 properties

JSON SCHEMA

Security Posture 2

Authentication, domain security, vulnerability disclosure, and trust-center signals.

ivive.app Authentication

1 scheme

SECURITY

ivive.app Domain Security

TLSv1.3 · HSTS

SECURITY

Scopes 1

OAuth scopes governing access to this provider's APIs.

ivive.app Scopes

OAuth 2.0 · no documented scopes

0 scopes

SCOPES

Agentic Access (API Evangelist recommendations) 1

Recommended x-agentic-access execution contracts for AI agents.

ivive.app Agentic Access

36 operations · 22 acting · 1 human-in-the-loop

36 operations · 22 acting

AGENTIC

Resources

Get Started 1

Portal, sign-up, and the first successful call

GettingStarted

GettingStarted

Documentation 2

Reference material describing how the API behaves

Documentation

Documentation

APIReference

APIReference

Agent Surfaces 4

MCP servers, agent skills, and machine-readable catalogs

AgenticAccess

AgentSkill

LLMsTxt

MCPServer

Design & Contract 6

Pagination, idempotency, versioning, errors, and events

Spectral

JSONLD

Vocabulary

DataModel

ErrorCatalog

Conformance

Access & Security 2

Authentication, authorization, and security posture

Authentication

Authentication

DomainSecurity

DomainSecurity

Operate 1

Status, limits, changes, and where to get help

Support

Support

Commercial 2

Pricing, plans, and the legal terms of use

TermsOfService

TermsOfService

PrivacyPolicy

PrivacyPolicy

Company 1

The organization behind the API

Website

Website

Other 1

Properties that don't map to a standard resource type

Hosts

Hosts

Source (apis.yml)

aid: ivive-app
name: ivive.app
accessModel:
  pricing: unknown
  onboarding: unknown
  trial: false
  try_now: false
  public: false
  label: Unknown
  confidence: low
  source:
  - authentication
  - security
  generated: '2026-11-13'
  method: derived
image: https://ivive.app/og.png
description: IVIVE.app provides a free in‑vitro to hepatic clearance calculator for drug discovery, offering batch calculations,
  species scaling, structure‑based predictions, and an MCP server for LLM integration. It features a web UI, REST API, and
  open‑source tools for scientists to predict clearance without an account.
url: https://artifacts.apis.io/ivive-app/apis.yml
x-type: company
x-source: harvest:mcp-registry
x-tier: profiled
x-tier-reason: enrichment pass 2026-11-12 (modular-v1; was harvest)
specificationVersion: '0.20'
created: '2026-11-12'
modified: '2026-11-12'
tags:
- Company
- IVIVE
- Drug Discovery
- HepaticClearance
- Open Source
tags_raw:
- Company
- IVIVE
- DrugDiscovery
- HepaticClearance
- OpenSource
maintainers:
- FN: Kin Lane
  email: kin@apievangelist.com
- FN: APIs.json
  email: info@apis.io
common:
- type: AgenticAccess
  url: agentic-access/ivive-app-agentic-access.yml
- type: Spectral
  url: rules/ivive-app-rules.yml
- type: JSONLD
  url: json-ld/ivive-app-context.jsonld
- type: Vocabulary
  url: vocabulary/ivive-app-vocabulary.yml
- type: AgentSkill
  url: skills/_index.yml
- type: DataModel
  url: data-model/ivive-app-data-model.yml
- type: Authentication
  url: authentication/ivive-app-authentication.yml
- type: ErrorCatalog
  url: errors/ivive-app-problem-types.yml
- type: Conformance
  url: conformance/ivive-app-conformance.yml
- type: LLMsTxt
  url: llms/ivive-app-llms.txt
- type: MCPServer
  url: mcp/ivive-app-mcp.yml
- type: Hosts
  url: hosts/ivive-app-hosts.yml
- type: DomainSecurity
  url: security/ivive-app-domain-security.yml
- type: Website
  url: https://ivive.app/
- type: Documentation
  url: https://api.ivive.app/docs
- type: APIReference
  url: https://api.ivive.app/openapi.json
- type: GettingStarted
  url: https://ivive.app/#how
- type: Support
  url: mailto:hello@ivive.app?subject=ivive%20feedback
- type: TermsOfService
  url: https://ivive.app/terms
- type: PrivacyPolicy
  url: https://ivive.app/privacy
apis:
- aid: ivive-app:ivive-app-auth-api
  name: ivive.app Auth API
  description: The auth API from ivive.app — 5 operation(s) for auth.
  humanURL: https://api.ivive.app/docs
  baseURL: https://api.ivive.app
  tags:
  - Authentication
  tags_raw:
  - auth
  properties:
  - type: OpenAPI
    url: openapi/ivive-app-auth-api-openapi.yml
  - type: JSONSchema
    url: json-schema/ivive-app-sensitivity-request-schema.json
  - type: JSONSchema
    url: json-schema/ivive-app-clhep-request-schema.json
  - type: JSONSchema
    url: json-schema/ivive-app-clhep-response-schema.json
  - type: JSONSchema
    url: json-schema/ivive-app-prediction-response-schema.json
  - type: JSONSchema
    url: json-schema/ivive-app-fit-response-schema.json
  - type: JSONSchema
    url: json-schema/ivive-app-model-detail-schema.json
- aid: ivive-app:ivive-app-correction-equations-api
  name: ivive.app Correction Equations API
  description: The correction-equations API from ivive.app — 3 operation(s) for correction-equations.
  humanURL: https://api.ivive.app/docs
  baseURL: https://api.ivive.app
  tags:
  - correction-equations
  properties:
  - type: OpenAPI
    url: openapi/ivive-app-correction-equations-api-openapi.yml
  - type: JSONSchema
    url: json-schema/ivive-app-sensitivity-request-schema.json
  - type: JSONSchema
    url: json-schema/ivive-app-clhep-request-schema.json
  - type: JSONSchema
    url: json-schema/ivive-app-clhep-response-schema.json
  - type: JSONSchema
    url: json-schema/ivive-app-prediction-response-schema.json
  - type: JSONSchema
    url: json-schema/ivive-app-fit-response-schema.json
  - type: JSONSchema
    url: json-schema/ivive-app-model-detail-schema.json
- aid: ivive-app:ivive-app-health-api
  name: ivive.app Health API
  description: The health API from ivive.app — 1 operation(s) for health.
  humanURL: https://api.ivive.app/docs
  baseURL: https://api.ivive.app
  tags:
  - Health
  tags_raw:
  - health
  properties:
  - type: OpenAPI
    url: openapi/ivive-app-health-api-openapi.yml
  - type: JSONSchema
    url: json-schema/ivive-app-sensitivity-request-schema.json
  - type: JSONSchema
    url: json-schema/ivive-app-clhep-request-schema.json
  - type: JSONSchema
    url: json-schema/ivive-app-clhep-response-schema.json
  - type: JSONSchema
    url: json-schema/ivive-app-prediction-response-schema.json
  - type: JSONSchema
    url: json-schema/ivive-app-fit-response-schema.json
  - type: JSONSchema
    url: json-schema/ivive-app-model-detail-schema.json
- aid: ivive-app:ivive-app-ivivc-api
  name: ivive.app Ivivc API
  description: The ivivc API from ivive.app — 6 operation(s) for ivivc.
  humanURL: https://api.ivive.app/docs
  baseURL: https://api.ivive.app
  tags:
  - ivivc
  properties:
  - type: OpenAPI
    url: openapi/ivive-app-ivivc-api-openapi.yml
  - type: JSONSchema
    url: json-schema/ivive-app-sensitivity-request-schema.json
  - type: JSONSchema
    url: json-schema/ivive-app-clhep-request-schema.json
  - type: JSONSchema
    url: json-schema/ivive-app-clhep-response-schema.json
  - type: JSONSchema
    url: json-schema/ivive-app-prediction-response-schema.json
  - type: JSONSchema
    url: json-schema/ivive-app-fit-response-schema.json
  - type: JSONSchema
    url: json-schema/ivive-app-model-detail-schema.json
- aid: ivive-app:ivive-app-ivive-api
  name: ivive.app Ivive API
  description: The ivive API from ivive.app — 4 operation(s) for ivive.
  humanURL: https://api.ivive.app/docs
  baseURL: https://api.ivive.app
  tags:
  - IVIVE
  tags_raw:
  - ivive
  properties:
  - type: OpenAPI
    url: openapi/ivive-app-ivive-api-openapi.yml
  - type: JSONSchema
    url: json-schema/ivive-app-sensitivity-request-schema.json
  - type: JSONSchema
    url: json-schema/ivive-app-clhep-request-schema.json
  - type: JSONSchema
    url: json-schema/ivive-app-clhep-response-schema.json
  - type: JSONSchema
    url: json-schema/ivive-app-prediction-response-schema.json
  - type: JSONSchema
    url: json-schema/ivive-app-fit-response-schema.json
  - type: JSONSchema
    url: json-schema/ivive-app-model-detail-schema.json
- aid: ivive-app:ivive-app-library-api
  name: ivive.app Library API
  description: The library API from ivive.app — 2 operation(s) for library.
  humanURL: https://api.ivive.app/docs
  baseURL: https://api.ivive.app
  tags:
  - Library
  tags_raw:
  - library
  properties:
  - type: OpenAPI
    url: openapi/ivive-app-library-api-openapi.yml
  - type: JSONSchema
    url: json-schema/ivive-app-sensitivity-request-schema.json
  - type: JSONSchema
    url: json-schema/ivive-app-clhep-request-schema.json
  - type: JSONSchema
    url: json-schema/ivive-app-clhep-response-schema.json
  - type: JSONSchema
    url: json-schema/ivive-app-prediction-response-schema.json
  - type: JSONSchema
    url: json-schema/ivive-app-fit-response-schema.json
  - type: JSONSchema
    url: json-schema/ivive-app-model-detail-schema.json
- aid: ivive-app:ivive-app-molecule-api
  name: ivive.app Molecule API
  description: The molecule API from ivive.app — 2 operation(s) for molecule.
  humanURL: https://api.ivive.app/docs
  baseURL: https://api.ivive.app
  tags:
  - Molecule
  tags_raw:
  - molecule
  properties:
  - type: OpenAPI
    url: openapi/ivive-app-molecule-api-openapi.yml
  - type: JSONSchema
    url: json-schema/ivive-app-sensitivity-request-schema.json
  - type: JSONSchema
    url: json-schema/ivive-app-clhep-request-schema.json
  - type: JSONSchema
    url: json-schema/ivive-app-clhep-response-schema.json
  - type: JSONSchema
    url: json-schema/ivive-app-prediction-response-schema.json
  - type: JSONSchema
    url: json-schema/ivive-app-fit-response-schema.json
  - type: JSONSchema
    url: json-schema/ivive-app-model-detail-schema.json
- aid: ivive-app:ivive-app-pk-api
  name: ivive.app Pk API
  description: The pk API from ivive.app — 1 operation(s) for pk.
  humanURL: https://api.ivive.app/docs
  baseURL: https://api.ivive.app
  tags:
  - pk
  properties:
  - type: OpenAPI
    url: openapi/ivive-app-pk-api-openapi.yml
  - type: JSONSchema
    url: json-schema/ivive-app-sensitivity-request-schema.json
  - type: JSONSchema
    url: json-schema/ivive-app-clhep-request-schema.json
  - type: JSONSchema
    url: json-schema/ivive-app-clhep-response-schema.json
  - type: JSONSchema
    url: json-schema/ivive-app-prediction-response-schema.json
  - type: JSONSchema
    url: json-schema/ivive-app-fit-response-schema.json
  - type: JSONSchema
    url: json-schema/ivive-app-model-detail-schema.json
- aid: ivive-app:ivive-app-prediction-api
  name: ivive.app Prediction API
  description: The prediction API from ivive.app — 5 operation(s) for prediction.
  humanURL: https://api.ivive.app/docs
  baseURL: https://api.ivive.app
  tags:
  - Predictions
  tags_raw:
  - prediction
  properties:
  - type: OpenAPI
    url: openapi/ivive-app-prediction-api-openapi.yml
  - type: JSONSchema
    url: json-schema/ivive-app-sensitivity-request-schema.json
  - type: JSONSchema
    url: json-schema/ivive-app-clhep-request-schema.json
  - type: JSONSchema
    url: json-schema/ivive-app-clhep-response-schema.json
  - type: JSONSchema
    url: json-schema/ivive-app-prediction-response-schema.json
  - type: JSONSchema
    url: json-schema/ivive-app-fit-response-schema.json
  - type: JSONSchema
    url: json-schema/ivive-app-model-detail-schema.json
- aid: ivive-app:ivive-app-reference-compounds-api
  name: ivive.app Reference Compounds API
  description: The reference-compounds API from ivive.app — 1 operation(s) for reference-compounds.
  humanURL: https://api.ivive.app/docs
  baseURL: https://api.ivive.app
  tags:
  - reference-compounds
  properties:
  - type: OpenAPI
    url: openapi/ivive-app-reference-compounds-api-openapi.yml
  - type: JSONSchema
    url: json-schema/ivive-app-sensitivity-request-schema.json
  - type: JSONSchema
    url: json-schema/ivive-app-clhep-request-schema.json
  - type: JSONSchema
    url: json-schema/ivive-app-clhep-response-schema.json
  - type: JSONSchema
    url: json-schema/ivive-app-prediction-response-schema.json
  - type: JSONSchema
    url: json-schema/ivive-app-fit-response-schema.json
  - type: JSONSchema
    url: json-schema/ivive-app-model-detail-schema.json
- aid: ivive-app:ivive-app-scaling-api
  name: ivive.app Scaling API
  description: The scaling API from ivive.app — 1 operation(s) for scaling.
  humanURL: https://api.ivive.app/docs
  baseURL: https://api.ivive.app
  tags:
  - Scaling
  tags_raw:
  - scaling
  properties:
  - type: OpenAPI
    url: openapi/ivive-app-scaling-api-openapi.yml
  - type: JSONSchema
    url: json-schema/ivive-app-sensitivity-request-schema.json
  - type: JSONSchema
    url: json-schema/ivive-app-clhep-request-schema.json
  - type: JSONSchema
    url: json-schema/ivive-app-clhep-response-schema.json
  - type: JSONSchema
    url: json-schema/ivive-app-prediction-response-schema.json
  - type: JSONSchema
    url: json-schema/ivive-app-fit-response-schema.json
  - type: JSONSchema
    url: json-schema/ivive-app-model-detail-schema.json
x-enrichment:
  date: '2026-11-12'
  status: enriched
  artifacts_added: 25
  pass: modular-v1
  engine: identity=local,contract=local,surfaces=local,docs=local,regulatory=local

ivive.app API — frequently asked questions

Does ivive.app have an API?

Yes. APIs.io lists 11 APIs from ivive.app, including ivive.app Auth API, ivive.app Correction Equations API and ivive.app Health API, and 8 more.

Is there an OpenAPI specification for the ivive.app API?

Yes. APIs.io indexes 11 OpenAPI specifications for ivive.app, each linked for download from this page.

How do I authenticate with the ivive.app API?

ivive.app uses bearer-token authentication (1 scheme). The details are profiled on APIs.io as ivive.app Authentication.

Does ivive.app have an MCP server?

Yes. APIs.io lists 1 MCP server for ivive.app: Remote MCP server at api.ivive.app.

Is the ivive.app API ready for AI agents?

ivive.app has a Kin Score of 38.4 out of 100 (thin) and an Agent Readiness score of 27.9 (agent-aware), scored by API Evangelist on 2026-11-13.

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