Agency for Toxic Substances and Disease Registry website screenshot

Agency for Toxic Substances and Disease Registry

ATSDR protects communities from harmful health effects related to exposure to natural and man-made hazardous substances. It is a federal public health agency within the U.S. Department of Health and Human Services. ATSDR provides toxicological profiles, minimum risk levels, substance priority rankings, and exposure investigation data for hazardous chemicals.

Agency for Toxic Substances and Disease Registry publishes 4 APIs on the APIs.io network, including Exposure Investigations API, Minimum Risk Levels API, Substance Priority List API, and 1 more. Tagged areas include Diseases, Federal-Government, Public Health, Toxic Substances, and Environmental Health.

The Agency for Toxic Substances and Disease Registry catalog on APIs.io includes 1 JSON-LD context and 2 Spectral governance rulesets.

Agency for Toxic Substances and Disease Registry’s developer surface includes developer portal, getting-started guide, documentation, and 12 more developer resources.

29.9/100 thin ▬ flat Agent 32/100 agent aware Full breakdown ↓
scored 2026-08-20 · rubric v0.12.0
AccessFreemium
4 APIs
DiseasesFederal-GovernmentPublic HealthToxic SubstancesEnvironmental HealthHazardous Materials

Kin Score

Kin Score Kin Score How this is scored →
scored 2026-08-20 · rubric v0.12.0
Composite quality — 29.9/100 · thin
Contract Quality 12.6 / 21
Developer Ergonomics 3.2 / 17
Access Clarity 0.0 / 17
Operational Transparency 0.9 / 11
Contract Governance 2.6 / 10
Discoverability 6.3 / 9
Regulatory Posture 3.1 / 15
Agent readiness — 32/100 · agent aware
Machine-Readable Contract 18 / 18
Agentic Access Contract 10 / 10
Documented Reversibility 6 / 6
MCP Server 0 / 12
Machine-Readable Auth 0 / 10
Idempotency 9 / 9
Stable Error Semantics 0 / 8
Request/Response Examples 7 / 7
Rate-Limit Signaling 7 / 7
Typed Event Surface 0 / 6
Agent Skills 0 / 5
Well-Known Catalog 0 / 4
Consent & Bot Identity 0 / 3
A2A Agent Card 0 / 8
Dry-Run / Simulate Mode 4 / 4
Regulatory Posture applies to this provider. Its tags matched the Government & Public Sector regime, so Regulatory Posture carries 15 points of the composite. If this regime is wrong for your business, say so on your provider repo — the applicability map is public and we will correct it.
The six quality facets above are damped to 85 points between them, because the conditional facet above carries the other 15. That is why each facet's contribution is shown against a damped maximum: raising a quality facet moves the composite by 85% of its nominal weight, not 100%. The full arithmetic is at apis.io/rating/.
Improve this rating by publishing the missing artifacts — every area above can be raised, and the full rubric is at apis.io/rating/. This rating is computed from github.com/api-evangelist/agency-for-toxic-substances-and-disease-registry: open an issue to ask a question, or submit a pull request to add artifacts. Want it done for you? Prioritized profiling — $2,500 →

APIs 4

Individual APIs this provider publishes, each with its own machine-readable definition.

Agency for Toxic Substances and Disease Registry Exposure Investigations API

The Exposure Investigations API from Agency for Toxic Substances and Disease Registry — 1 operation(s) for exposure investigations.

Agency for Toxic Substances and Disease Registry Minimum Risk Levels API

The Minimum Risk Levels API from Agency for Toxic Substances and Disease Registry — 1 operation(s) for minimum risk levels.

Agency for Toxic Substances and Disease Registry Substance Priority List API

The Substance Priority List API from Agency for Toxic Substances and Disease Registry — 1 operation(s) for substance priority list.

Agency for Toxic Substances and Disease Registry Toxicological Profiles API

The Toxicological Profiles API from Agency for Toxic Substances and Disease Registry — 1 operation(s) for toxicological profiles.

Open Collections 6

Open, tool-agnostic API collections (OpenAPI-derived and Bruno).

API Collection

OPEN COLLECTION

Pricing Plans 1

Published pricing tiers and plan structures.

Rate Limits 1

Documented rate limits and quota policies.

FinOps 1

Cost, billing, and metering signals for API financial operations.

Semantic Vocabularies 1

JSON-LD contexts and semantic vocabularies used across these APIs.

Spectral Rules 2

Spectral governance rulesets for linting and validating these APIs.

Agency for Toxic Substances and Disease Registry API Rules

5 rules · 4 warnings 1 info

SPECTRAL

Agency for Toxic Substances and Disease Registry API Rules

27 rules · 14 errors 13 warnings

SPECTRAL

JSON Schema 4

Standalone JSON Schema definitions for this provider's data models.

ExposureInvestigation

7 properties

JSON SCHEMA

MinimumRiskLevel

7 properties

JSON SCHEMA

SubstancePriority

7 properties

JSON SCHEMA

ToxProfile

7 properties

JSON SCHEMA

JSON Structure 4

JSON Structure definitions describing this provider's data shapes.

Examples 4

Example request and response payloads for these APIs.

Security Posture 1

Authentication, domain security, vulnerability disclosure, and trust-center signals.

Agency For Toxic Substances And Disease Registry Domain Security

TLSv1.3 · HSTS · DNSSEC · DMARC

SECURITY

Agentic Access 1

Recommended x-agentic-access execution contracts for AI agents.

Agency For Toxic Substances And Disease Registry Agentic Access

4 operations

4 operations · 0 acting

AGENTIC

Resources

Get Started 3

Portal, sign-up, and the first successful call

Documentation 4

Reference material describing how the API behaves

Agent Surfaces 1

MCP servers, agent skills, and machine-readable catalogs

Design & Contract 3

Pagination, idempotency, versioning, errors, and events

Access & Security 1

Authentication, authorization, and security posture

Company 2

The organization behind the API

Other 1

Properties that don't map to a standard resource type

Source (apis.yml)

apis.yml Raw ↑
aid: agency-for-toxic-substances-and-disease-registry
url: https://raw.githubusercontent.com/api-evangelist/agency-for-toxic-substances-and-disease-registry/refs/heads/main/apis.yml
name: Agency for Toxic Substances and Disease Registry
type: Index
accessModel:
  pricing: freemium
  onboarding: unknown
  trial: false
  try_now: false
  public: false
  label: Freemium
  confidence: medium
  source:
  - plans
  generated: '2026-07-22'
  method: derived
image: https://kinlane-images.s3.amazonaws.com/shared/apis-json/icons/agency-for-toxic-substances-and-disease-registry.png
tags:
- Diseases
- Federal-Government
- Public Health
- Toxic Substances
- Environmental Health
- Hazardous Materials
tags_raw:
- Diseases
- Federal Government
- Public Health
- Toxic Substances
- Environmental Health
- Hazardous Materials
description: ATSDR protects communities from harmful health effects related to exposure to natural and man-made hazardous
  substances. It is a federal public health agency within the U.S. Department of Health and Human Services. ATSDR provides
  toxicological profiles, minimum risk levels, substance priority rankings, and exposure investigation data for hazardous
  chemicals.
created: '2024-11-21'
modified: '2026-05-19'
specificationVersion: '0.23'
apis:
- aid: agency-for-toxic-substances-and-disease-registry:agency-for-toxic-substances-and-disease-registry-exposure-investigations-api
  name: Agency for Toxic Substances and Disease Registry Exposure Investigations API
  description: The Exposure Investigations API from Agency for Toxic Substances and Disease Registry — 1 operation(s) for
    exposure investigations.
  humanURL: https://www.atsdr.cdc.gov/substances/index.asp
  baseURL: https://data.cdc.gov/resource
  tags:
  - Exposure Investigations
  properties:
  - type: OpenAPI
    url: openapi/agency-for-toxic-substances-and-disease-registry-exposure-investigations-api-openapi.yml
  - type: Documentation
    url: https://www.atsdr.cdc.gov/substances/index.asp
  - type: Documentation
    url: https://www.atsdr.cdc.gov/mrls/index.asp
- aid: agency-for-toxic-substances-and-disease-registry:agency-for-toxic-substances-and-disease-registry-minimum-risk-levels-api
  name: Agency for Toxic Substances and Disease Registry Minimum Risk Levels API
  description: The Minimum Risk Levels API from Agency for Toxic Substances and Disease Registry — 1 operation(s) for minimum
    risk levels.
  humanURL: https://www.atsdr.cdc.gov/substances/index.asp
  baseURL: https://data.cdc.gov/resource
  tags:
  - Minimum Risk Levels
  properties:
  - type: OpenAPI
    url: openapi/agency-for-toxic-substances-and-disease-registry-minimum-risk-levels-api-openapi.yml
  - type: Documentation
    url: https://www.atsdr.cdc.gov/substances/index.asp
  - type: Documentation
    url: https://www.atsdr.cdc.gov/mrls/index.asp
- aid: agency-for-toxic-substances-and-disease-registry:agency-for-toxic-substances-and-disease-registry-substance-priority-list-api
  name: Agency for Toxic Substances and Disease Registry Substance Priority List API
  description: The Substance Priority List API from Agency for Toxic Substances and Disease Registry — 1 operation(s) for
    substance priority list.
  humanURL: https://www.atsdr.cdc.gov/substances/index.asp
  baseURL: https://data.cdc.gov/resource
  tags:
  - Substance Priority List
  properties:
  - type: OpenAPI
    url: openapi/agency-for-toxic-substances-and-disease-registry-substance-priority-list-api-openapi.yml
  - type: Documentation
    url: https://www.atsdr.cdc.gov/substances/index.asp
  - type: Documentation
    url: https://www.atsdr.cdc.gov/mrls/index.asp
- aid: agency-for-toxic-substances-and-disease-registry:agency-for-toxic-substances-and-disease-registry-toxicological-profiles-api
  name: Agency for Toxic Substances and Disease Registry Toxicological Profiles API
  description: The Toxicological Profiles API from Agency for Toxic Substances and Disease Registry — 1 operation(s) for toxicological
    profiles.
  humanURL: https://www.atsdr.cdc.gov/substances/index.asp
  baseURL: https://data.cdc.gov/resource
  tags:
  - Toxicological Profiles
  properties:
  - type: OpenAPI
    url: openapi/agency-for-toxic-substances-and-disease-registry-toxicological-profiles-api-openapi.yml
  - type: Documentation
    url: https://www.atsdr.cdc.gov/substances/index.asp
  - type: Documentation
    url: https://www.atsdr.cdc.gov/mrls/index.asp
common:
- type: AgenticAccess
  url: agentic-access/agency-for-toxic-substances-and-disease-registry-agentic-access.yml
- type: DomainSecurity
  url: security/agency-for-toxic-substances-and-disease-registry-domain-security.yml
- type: LinkedIn
  url: https://www.linkedin.com/company/agency-for-toxic-substances-and-disease-registry
- type: Website
  url: https://www.atsdr.cdc.gov/
- type: Portal
  url: https://www.atsdr.cdc.gov/api
- type: DataPortal
  url: https://data.cdc.gov/browse?category=Environmental+Health
- type: GettingStarted
  url: https://www.atsdr.cdc.gov/substances/index.asp
- type: Documentation
  url: https://www.atsdr.cdc.gov/mrls/index.asp
- type: Documentation
  url: https://www.atsdr.cdc.gov/spl/index.html
- type: FOIA
  url: https://www.hhs.gov/foia/index.html
- url: https://raw.githubusercontent.com/api-evangelist/agency-for-toxic-substances-and-disease-registry/refs/heads/main/rules/atsdr-spectral-rules.yml
  type: SpectralRules
- url: https://raw.githubusercontent.com/api-evangelist/agency-for-toxic-substances-and-disease-registry/refs/heads/main/json-schema/atsdr-tox-profile-schema.json
  type: JSONSchema
- url: https://raw.githubusercontent.com/api-evangelist/agency-for-toxic-substances-and-disease-registry/refs/heads/main/json-schema/atsdr-mrl-schema.json
  type: JSONSchema
- url: https://raw.githubusercontent.com/api-evangelist/agency-for-toxic-substances-and-disease-registry/refs/heads/main/json-ld/atsdr-toxicology-context.jsonld
  type: JSONLDContext
- url: https://raw.githubusercontent.com/api-evangelist/agency-for-toxic-substances-and-disease-registry/refs/heads/main/vocabulary/atsdr-vocabulary.yaml
  type: Vocabulary
maintainers:
- FN: Kin Lane
  email: kin@apievangelist.com