Agency for Toxic Substances and Disease Registry

ATSDR protects communities from harmful health effects related to exposure to natural and man-made hazardous substances. It is a federal public health agency within the U.S. Department of Health and Human Services. ATSDR provides toxicological profiles, minimum risk levels, substance priority rankings, and exposure investigation data for hazardous chemicals.

Agency for Toxic Substances and Disease Registry publishes 4 APIs on the APIs.io network, including Exposure Investigations API, Minimum Risk Levels API, Substance Priority List API, and 1 more. Tagged areas include Diseases, Federal-Government, Public Health, Toxic Substances, and Environmental Health.

The Agency for Toxic Substances and Disease Registry catalog on APIs.io includes 1 JSON-LD context and 2 Spectral governance rulesets.

Agency for Toxic Substances and Disease Registry’s developer surface includes developer portal, getting-started guide, documentation, and 12 more developer resources.

🌐 Visit website 📡 Source on GitHub

29.4/100 thin ▬ flat Agent 26/100 agent aware Full breakdown ↓
scored 2026-09-08 · rubric v0.20.0

AccessFreemium

1 APIs

Diseases Federal-Government Public HealthToxic SubstancesEnvironmental Health Hazardous Materials

Kin Score

Kin Score How this is scored →
scored 2026-09-08 · rubric v0.20.0

Composite quality — 29.4/100 · thin

Contract Quality 12.3 / 21

Developer Ergonomics 3.2 / 17

Access Clarity 0.0 / 17

Operational Transparency 0.9 / 11

Contract Governance 2.9 / 10

Discoverability 5.8 / 9

Regulatory Posture 3.1 / 15

Agent readiness — 26/100 · agent aware

Machine-Readable Contract 18 / 18

Agentic Access Contract 10 / 10

Documented Reversibility 6 / 6

MCP Server 0 / 12

Machine-Readable Auth 0 / 10

Idempotency 9 / 9

Stable Error Semantics 0 / 8

Request/Response Examples 7 / 7

Rate-Limit Signaling 7 / 7

Typed Event Surface 0 / 6

Agent Skills 0 / 5

Well-Known Catalog 0 / 4

Consent & Bot Identity 0 / 3

A2A Agent Card 0 / 8

Dry-Run / Simulate Mode 4 / 4

Delegated User Identity 0 / 6

Protected Resource Metadata 0 / 5

Registration Without a Human 0 / 6

Agentic Commerce Well-Known Document 0 / 5

Regulatory Posture applies to this provider. Its tags matched the Government & Public Sector regime, so Regulatory Posture carries 15 points of the composite. If this regime is wrong for your business, say so on your provider repo — the applicability map is public and we will correct it.

Create-or-Update Ergonomics does not apply to this provider. The published contracts declare no write operations, and a read-only API cannot create-or-update. The facet is excluded from this provider's denominator entirely — not scored zero. A reference or data API is not deficient for being unable to upsert.

The six quality facets above are damped to 85 points between them, because the conditional facet above carries the other 15. That is why each facet's contribution is shown against a damped maximum: raising a quality facet moves the composite by 85% of its nominal weight, not 100%. The full arithmetic is at apis.io/rating/.

Improve this rating by publishing the missing artifacts — every area above can be raised, and the full rubric is at apis.io/rating/. Every facet and dimension name above is a link: it opens that measurement's own page — what it means, the exact checks that feed it, how the whole catalog distributes on it, and the providers at the top of it. This rating is computed from github.com/api-evangelist/agency-for-toxic-substances-and-disease-registry: open an issue to ask a question, or submit a pull request to add artifacts. Submit an artifact on GitHub — free → Manage your own listing — the Influence plan, $499/mo →

APIs 4

Individual APIs this provider publishes, each with its own machine-readable definition.

Agency for Toxic Substances and Disease Registry Exposure Investigations API

The Exposure Investigations API from Agency for Toxic Substances and Disease Registry — 1 operation(s) for exposure investigations.

Agency for Toxic Substances and Disease Registry Minimum Risk Levels API

The Minimum Risk Levels API from Agency for Toxic Substances and Disease Registry — 1 operation(s) for minimum risk levels.

Agency for Toxic Substances and Disease Registry Substance Priority List API

The Substance Priority List API from Agency for Toxic Substances and Disease Registry — 1 operation(s) for substance priority list.

Agency for Toxic Substances and Disease Registry Toxicological Profiles API

The Toxicological Profiles API from Agency for Toxic Substances and Disease Registry — 1 operation(s) for toxicological profiles.

Open Collections 6

Open, tool-agnostic API collections (OpenAPI-derived and Bruno).

API Collection

OPEN COLLECTION

ATSDR Toxic Substance Profiles Exposure Investigations API

OPEN COLLECTION

ATSDR Toxic Substance Profiles Exposure Investigations Minimum Risk Levels API

OPEN COLLECTION

ATSDR Toxic Substance Profiles Exposure Investigations Substance Priority List API

OPEN COLLECTION

ATSDR Toxic Substance Profiles Exposure Investigations Toxicological Profiles API

OPEN COLLECTION

ATSDR Toxic Substance Profiles API

OPEN COLLECTION

Pricing Plans 1

Published pricing tiers and plan structures.

Agency For Toxic Substances And Disease Registry Plans Pricing

3 plans

PLANS

Rate Limits 1

Documented rate limits and quota policies.

Agency For Toxic Substances And Disease Registry Rate Limits

5 limits

RATE LIMITS

FinOps 1

Cost, billing, and metering signals for API financial operations.

Agency For Toxic Substances And Disease Registry Finops

FINOPS

Semantic Vocabularies 1

JSON-LD contexts and semantic vocabularies used across these APIs.

Agency For Toxic Substances And Disease Registry Atsdr Context

4 classes · 23 properties

JSON-LD

Spectral Rules 2

Spectral governance rulesets for linting and validating these APIs.

Agency for Toxic Substances and Disease Registry API Rules

5 rules · 4 warnings 1 info

SPECTRAL

Agency for Toxic Substances and Disease Registry API Rules

27 rules · 14 errors 13 warnings

SPECTRAL

JSON Schema 4

Standalone JSON Schema definitions for this provider's data models.

ExposureInvestigation

7 properties

JSON SCHEMA

MinimumRiskLevel

7 properties

JSON SCHEMA

SubstancePriority

7 properties

JSON SCHEMA

ToxProfile

7 properties

JSON SCHEMA

JSON Structure 4

JSON Structure definitions describing this provider's data shapes.

Atsdr Toxic Substance Profiles Exposure Investigation Structure

7 properties

JSON STRUCTURE

Atsdr Toxic Substance Profiles Minimum Risk Level Structure

7 properties

JSON STRUCTURE

Atsdr Toxic Substance Profiles Substance Priority Structure

7 properties

JSON STRUCTURE

Atsdr Toxic Substance Profiles Tox Profile Structure

7 properties

JSON STRUCTURE

Examples 4

Example request and response payloads for these APIs.

Atsdr Toxic Substance Profiles Exposure Investigation Example

7 fields

EXAMPLE

Atsdr Toxic Substance Profiles Minimum Risk Level Example

7 fields

EXAMPLE

Atsdr Toxic Substance Profiles Substance Priority Example

7 fields

EXAMPLE

Atsdr Toxic Substance Profiles Tox Profile Example

7 fields

EXAMPLE

Security Posture 1

Authentication, domain security, vulnerability disclosure, and trust-center signals.

Agency For Toxic Substances And Disease Registry Domain Security

TLSv1.3 · HSTS · DNSSEC · DMARC

SECURITY

Agentic Access 1

Recommended x-agentic-access execution contracts for AI agents.

Agency For Toxic Substances And Disease Registry Agentic Access

4 operations

4 operations · 0 acting

AGENTIC

Resources

Get Started 3

Portal, sign-up, and the first successful call

Portal

Portal

DataPortal

DataPortal

GettingStarted

GettingStarted

Documentation 4

Reference material describing how the API behaves

Documentation

Documentation

JSONSchema

JSONSchema

Agent Surfaces 1

MCP servers, agent skills, and machine-readable catalogs

AgenticAccess

AgenticAccess

Design & Contract 3

Pagination, idempotency, versioning, errors, and events

SpectralRules

SpectralRules

JSONLDContext

JSONLDContext

Vocabulary

Vocabulary

Access & Security 1

Authentication, authorization, and security posture

DomainSecurity

DomainSecurity

Company 2

The organization behind the API

LinkedIn

Website

Website

Other 1

Properties that don't map to a standard resource type

FOIA

FOIA

Source (apis.yml)

aid: agency-for-toxic-substances-and-disease-registry
url: https://raw.githubusercontent.com/api-evangelist/agency-for-toxic-substances-and-disease-registry/refs/heads/main/apis.yml
name: Agency for Toxic Substances and Disease Registry
type: Index
deliveryModel:
  model: unknown
  open_source: false
  commercial: false
  callable_host: true
  label: Delivery model not determined — needs a product licence on record
  confidence: low
  source:
  - openapi
  generated: '2026-08-28'
  method: derived
accessModel:
  pricing: freemium
  onboarding: unknown
  trial: false
  try_now: false
  public: false
  label: Freemium
  confidence: medium
  source:
  - plans
  generated: '2026-07-22'
  method: derived
image: https://kinlane-images.s3.amazonaws.com/shared/apis-json/icons/agency-for-toxic-substances-and-disease-registry.png
tags:
- Diseases
- Federal-Government
- Public Health
- Toxic Substances
- Environmental Health
- Hazardous Materials
tags_raw:
- Diseases
- Federal Government
- Public Health
- Toxic Substances
- Environmental Health
- Hazardous Materials
description: ATSDR protects communities from harmful health effects related to exposure to natural and man-made hazardous
  substances. It is a federal public health agency within the U.S. Department of Health and Human Services. ATSDR provides
  toxicological profiles, minimum risk levels, substance priority rankings, and exposure investigation data for hazardous
  chemicals.
created: '2024-11-21'
modified: '2026-05-19'
specificationVersion: '0.23'
apis:
- aid: agency-for-toxic-substances-and-disease-registry:agency-for-toxic-substances-and-disease-registry-exposure-investigations-api
  name: Agency for Toxic Substances and Disease Registry Exposure Investigations API
  description: The Exposure Investigations API from Agency for Toxic Substances and Disease Registry — 1 operation(s) for
    exposure investigations.
  humanURL: https://www.atsdr.cdc.gov/substances/index.asp
  baseURL: https://data.cdc.gov/resource
  tags:
  - Exposure Investigations
  properties:
  - type: OpenAPI
    url: openapi/agency-for-toxic-substances-and-disease-registry-exposure-investigations-api-openapi.yml
  - type: Documentation
    url: https://www.atsdr.cdc.gov/substances/index.asp
  - type: Documentation
    url: https://www.atsdr.cdc.gov/mrls/index.asp
- aid: agency-for-toxic-substances-and-disease-registry:agency-for-toxic-substances-and-disease-registry-minimum-risk-levels-api
  name: Agency for Toxic Substances and Disease Registry Minimum Risk Levels API
  description: The Minimum Risk Levels API from Agency for Toxic Substances and Disease Registry — 1 operation(s) for minimum
    risk levels.
  humanURL: https://www.atsdr.cdc.gov/substances/index.asp
  baseURL: https://data.cdc.gov/resource
  tags:
  - Minimum Risk Levels
  properties:
  - type: OpenAPI
    url: openapi/agency-for-toxic-substances-and-disease-registry-minimum-risk-levels-api-openapi.yml
  - type: Documentation
    url: https://www.atsdr.cdc.gov/substances/index.asp
  - type: Documentation
    url: https://www.atsdr.cdc.gov/mrls/index.asp
- aid: agency-for-toxic-substances-and-disease-registry:agency-for-toxic-substances-and-disease-registry-substance-priority-list-api
  name: Agency for Toxic Substances and Disease Registry Substance Priority List API
  description: The Substance Priority List API from Agency for Toxic Substances and Disease Registry — 1 operation(s) for
    substance priority list.
  humanURL: https://www.atsdr.cdc.gov/substances/index.asp
  baseURL: https://data.cdc.gov/resource
  tags:
  - Substance Priority List
  properties:
  - type: OpenAPI
    url: openapi/agency-for-toxic-substances-and-disease-registry-substance-priority-list-api-openapi.yml
  - type: Documentation
    url: https://www.atsdr.cdc.gov/substances/index.asp
  - type: Documentation
    url: https://www.atsdr.cdc.gov/mrls/index.asp
- aid: agency-for-toxic-substances-and-disease-registry:agency-for-toxic-substances-and-disease-registry-toxicological-profiles-api
  name: Agency for Toxic Substances and Disease Registry Toxicological Profiles API
  description: The Toxicological Profiles API from Agency for Toxic Substances and Disease Registry — 1 operation(s) for toxicological
    profiles.
  humanURL: https://www.atsdr.cdc.gov/substances/index.asp
  baseURL: https://data.cdc.gov/resource
  tags:
  - Toxicological Profiles
  properties:
  - type: OpenAPI
    url: openapi/agency-for-toxic-substances-and-disease-registry-toxicological-profiles-api-openapi.yml
  - type: Documentation
    url: https://www.atsdr.cdc.gov/substances/index.asp
  - type: Documentation
    url: https://www.atsdr.cdc.gov/mrls/index.asp
common:
- type: AgenticAccess
  url: agentic-access/agency-for-toxic-substances-and-disease-registry-agentic-access.yml
- type: DomainSecurity
  url: security/agency-for-toxic-substances-and-disease-registry-domain-security.yml
- type: LinkedIn
  url: https://www.linkedin.com/company/agency-for-toxic-substances-and-disease-registry
- type: Website
  url: https://www.atsdr.cdc.gov/
- type: Portal
  url: https://www.atsdr.cdc.gov/api
- type: DataPortal
  url: https://data.cdc.gov/browse?category=Environmental+Health
- type: GettingStarted
  url: https://www.atsdr.cdc.gov/substances/index.asp
- type: Documentation
  url: https://www.atsdr.cdc.gov/mrls/index.asp
- type: Documentation
  url: https://www.atsdr.cdc.gov/spl/index.html
- type: FOIA
  url: https://www.hhs.gov/foia/index.html
- url: https://raw.githubusercontent.com/api-evangelist/agency-for-toxic-substances-and-disease-registry/refs/heads/main/rules/atsdr-spectral-rules.yml
  type: SpectralRules
- url: https://raw.githubusercontent.com/api-evangelist/agency-for-toxic-substances-and-disease-registry/refs/heads/main/json-schema/atsdr-tox-profile-schema.json
  type: JSONSchema
- url: https://raw.githubusercontent.com/api-evangelist/agency-for-toxic-substances-and-disease-registry/refs/heads/main/json-schema/atsdr-mrl-schema.json
  type: JSONSchema
- url: https://raw.githubusercontent.com/api-evangelist/agency-for-toxic-substances-and-disease-registry/refs/heads/main/json-ld/atsdr-toxicology-context.jsonld
  type: JSONLDContext
- url: https://raw.githubusercontent.com/api-evangelist/agency-for-toxic-substances-and-disease-registry/refs/heads/main/vocabulary/atsdr-vocabulary.yaml
  type: Vocabulary
maintainers:
- FN: Kin Lane
  email: kin@apievangelist.com

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