STRING website screenshot

STRING

STRING is a protein-protein interaction network database providing scored associations between proteins across thousands of organisms. The REST API enables programmatic access to interaction scores, network visualizations, functional enrichment analysis, homology data, and protein annotations. STRING integrates data from genomic context, co-expression, text mining, biochemical and genetic experiments, and curated databases.

STRING publishes 7 API contracts indexed on the APIs.io network, including Annotation API, Enrichment API, Homology API, and 4 more. Tagged areas include Bioinformatics, Proteins, Genomics, Life Sciences, and Research.

The STRING catalog on APIs.io includes 1 JSON-LD context and 1 Spectral governance ruleset.

STRING’s developer surface includes engineering blog and 10 more developer resources.

27.3/100 thin ▬ flat Agent 29/100 agent ready Front door AI 1/6 silent saas Full breakdown ↓
scored 2026-11-06 · rubric v0.27.0 · Show this score on your site →
AccessFree
1 published contract 1 MCP Servers
BioinformaticsProteinsGenomicsLife SciencesResearchOpen Data

Kin Score

Kin Score Kin Score How this is scored →
scored 2026-11-06 · rubric v0.27.0
Regulatory Posture applies to this provider. Its tags matched the Health regime, so Regulatory Posture carries 15 points of the composite. If this regime is wrong for your business, say so on your provider repo — the applicability map is public and we will correct it.
Create-or-Update Ergonomics applies to this provider. This API accepts writes, so it carries 10 points of the composite. It is scored from the published contracts themselves: whether a caller can create-or-update in one call, whether the write accepts a key the caller already holds, and whether the response says which branch ran. Without that, every write needs a search-and-branch in front of it, and the first time that check is skipped a duplicate record is created. Scored against the observed mean rather than raw — a provider at the catalog average is unchanged by this facet, not penalised by it.
The six quality facets above are damped to 75 points between them, because the conditional facet above carries the other 25. That is why each facet's contribution is shown against a damped maximum: raising a quality facet moves the composite by 75% of its nominal weight, not 100%. The full arithmetic is at apis.io/rating/.
Show this score on your site. Kin Score badge preview for STRING It updates itself when the score changes. Paste this where you link to your API docs:
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Agent readiness — checks not met, largest first (exact, from this profile):
  • Agentic Access Contract +10 pts — agentic_access artifact present (x-agentic-access), graded by author
  • Idempotency +9 pts — OpenAPI mutating operations declare an idempotency key — a header, a request-body property, or a named de-duplication token whose own description says so (verified); else common[].type matches /idempoten/i (documented)
  • Stable Error Semantics +8 pts — OpenAPI $refs a shared error schema across 4xx/5xx responses (verified), else common[].type includes ErrorCatalog / ErrorCodes / DeclineCodes
  • A2A Agent Card +8 pts — a2a/-a2a.yml manifest, graded on conformance.grade against A2A 1.0.0
  • Registration Without a Human +6 pts — a `registration_endpoint` in the served RFC 8414 / OIDC discovery document
  • Delegated User Identity +6 pts — a served discovery document listing authorization_code in grant_types_supported (served), else an oauth2 authorizationCode flow or openIdConnect declared in an OpenAPI (documented)
9 more unmet checks in the Agent Readiness table above.
Kin Score — facets with the most composite points still available (weight × headroom):
Each check links to what satisfies it. Publish the artifact, or tell us where it already lives, and the score moves on the next scoring run.
Improve this rating by publishing the missing artifacts — every area above can be raised, and the full rubric is at apis.io/rating/. Every facet and dimension name above is a link: it opens that measurement's own page — what it means, the exact checks that feed it, how the whole catalog distributes on it, and the providers at the top of it. This rating is computed from the provider profile at artifacts.apis.io/string-db/apis.yml: open an issue on github.com/api-evangelist/string-db to ask a question or point us at an artifact you publish. Submit an artifact on GitHub — free → Manage your own listing — the Influence plan, $499/mo →

Standards implemented 2

Standards this provider implements or carries. De facto ones are profiled and measured by the API Commons; formal ones come from the standards directory and are linked by the provider's own tags. The evidence column says how each claim was established — not that it was made.

measured — observed by APIs.io (verified)
measured — observed by APIs.io (published)

APIs 7

Individual APIs this provider publishes, each with its own machine-readable definition.

STRING Annotation API

Functional annotations and term lookup

STRING Enrichment API

Functional enrichment analysis

STRING Homology API

Protein homology and similarity scores

STRING Identifiers API

Map protein names and synonyms to STRING identifiers

STRING Network API

Retrieve protein-protein interaction networks

STRING Utility API

Utility endpoints (version, links, API key)

STRING Valuesranks API

Values/Ranks GSEA-like enrichment (requires API key)

Scroll for all 7

Open Collections 7

Open, tool-agnostic API collections (OpenAPI-derived and Bruno).

STRING REST Homology API

OPEN COLLECTION

STRING REST Network API

OPEN COLLECTION

STRING REST Utility API

OPEN COLLECTION

Scroll for all 7

MCP Servers 1

Model Context Protocol servers that expose these APIs to AI agents.

STRING MCP Server

Remote MCP server at mcp.string-db.org over HTTP; 17 tools listed.

MCP SERVER

STRING API pricing

Not yet checked against STRING's own pricing page. Compiled by API Evangelist; confirm before you rely on a figure. A free plan or tier is listed.

PlanPrice
Open Access Free
Values/Ranks Enrichment (API Key) Free

Plan details, limits and sources →

Pricing Plans 1

Published pricing tiers and plan structures.

Plans

2 plans

PLANS

Rate Limits 1

Documented rate limits and quota policies.

Rate Limits

2 limits

RATE LIMITS

Service Levels 1

Uptime the provider promises or reports, as SLA4OAI. Read from its own pages; APIs.io runs no monitors.

STRING

SLA

FinOps 1

Cost, billing, and metering signals for API financial operations.

Finops

FINOPS

Semantic Vocabularies 1

JSON-LD contexts and semantic vocabularies used across these APIs.

context Context

0 classes · 38 properties

JSON-LD

Spectral Rules 1

Spectral governance rulesets for linting and validating these APIs.

STRING — jsonschema rules

5 rules · 3 warnings 2 info

SPECTRAL

JSON Schema 3

Standalone JSON Schema definitions for this provider's data models.

EnrichmentResult

10 properties

JSON SCHEMA

Interaction

13 properties

JSON SCHEMA

StringIdMapping

6 properties

JSON SCHEMA

Examples 4

Example request and response payloads for these APIs.

Functional Enrichment

3 fields

EXAMPLE

Get Interaction Partners

3 fields

EXAMPLE

Get String Ids

3 fields

EXAMPLE

Ppi Enrichment

3 fields

EXAMPLE

Security Posture 1

Authentication, domain security, vulnerability disclosure, and trust-center signals.

String Db Domain Security

TLSv1.3

SECURITY

Resources

Documentation 2

Reference material describing how the API behaves

Access & Security 1

Authentication, authorization, and security posture

Operate 1

Status, limits, changes, and where to get help

Commercial 3

Pricing, plans, and the legal terms of use

Company 2

The organization behind the API

Other 2

Properties that don't map to a standard resource type

Source (apis.yml)

apis.yml Raw ↑
name: STRING
description: 'STRING is a protein-protein interaction network database providing scored associations between proteins across
  thousands of organisms. The REST API enables programmatic access to interaction scores, network visualizations, functional
  enrichment analysis, homology data, and protein annotations. STRING integrates data from genomic context, co-expression,
  text mining, biochemical and genetic experiments, and curated databases.

  '
deliveryModel:
  model: saas
  open_source: false
  commercial: true
  callable_host: true
  label: Hosted service · you call their endpoint
  confidence: high
  source:
  - openapi
  - pricing
  generated: '2026-08-28'
  method: derived
specificationVersion: '0.23'
accessModel:
  pricing: free
  onboarding: unknown
  trial: false
  try_now: false
  public: false
  label: Free
  confidence: low
  source:
  - plans
  - security
  generated: '2026-11-06'
  method: derived
image: https://string-db.org/images/logo/logo_medium.png
tags:
- Bioinformatics
- Proteins
- Genomics
- Life Sciences
- Research
- Open Data
url: https://string-db.org
apis:
- aid: string-db:string-db-annotation-api
  name: STRING Annotation API
  description: Functional annotations and term lookup
  humanURL: https://string-db.org/help/api/
  tags:
  - Annotation
  tags_raw:
  - annotation
  properties:
  - type: OpenAPI
    url: openapi/string-db-annotation-api-openapi.yml
  - type: Documentation
    url: https://string-db.org/help/api/
- aid: string-db:string-db-enrichment-api
  name: STRING Enrichment API
  description: Functional enrichment analysis
  humanURL: https://string-db.org/help/api/
  tags:
  - Data Enrichment
  tags_raw:
  - enrichment
  properties:
  - type: OpenAPI
    url: openapi/string-db-enrichment-api-openapi.yml
  - type: Documentation
    url: https://string-db.org/help/api/
- aid: string-db:string-db-homology-api
  name: STRING Homology API
  description: Protein homology and similarity scores
  humanURL: https://string-db.org/help/api/
  tags:
  - Homology
  tags_raw:
  - homology
  properties:
  - type: OpenAPI
    url: openapi/string-db-homology-api-openapi.yml
  - type: Documentation
    url: https://string-db.org/help/api/
- aid: string-db:string-db-identifiers-api
  name: STRING Identifiers API
  description: Map protein names and synonyms to STRING identifiers
  humanURL: https://string-db.org/help/api/
  tags:
  - Identifiers
  tags_raw:
  - identifiers
  properties:
  - type: OpenAPI
    url: openapi/string-db-identifiers-api-openapi.yml
  - type: Documentation
    url: https://string-db.org/help/api/
- aid: string-db:string-db-network-api
  name: STRING Network API
  description: Retrieve protein-protein interaction networks
  humanURL: https://string-db.org/help/api/
  tags:
  - Networks
  tags_raw:
  - network
  properties:
  - type: OpenAPI
    url: openapi/string-db-network-api-openapi.yml
  - type: Documentation
    url: https://string-db.org/help/api/
- aid: string-db:string-db-utility-api
  name: STRING Utility API
  description: Utility endpoints (version, links, API key)
  humanURL: https://string-db.org/help/api/
  tags:
  - Utility
  tags_raw:
  - utility
  properties:
  - type: OpenAPI
    url: openapi/string-db-utility-api-openapi.yml
  - type: Documentation
    url: https://string-db.org/help/api/
- aid: string-db:string-db-valuesranks-api
  name: STRING Valuesranks API
  description: Values/Ranks GSEA-like enrichment (requires API key)
  humanURL: https://string-db.org/help/api/
  tags:
  - valuesranks
  properties:
  - type: OpenAPI
    url: openapi/string-db-valuesranks-api-openapi.yml
  - type: Documentation
    url: https://string-db.org/help/api/
common:
- type: Plans
  url: plans/plans.yml
- type: RateLimits
  url: rate-limits/rate-limits.yml
- type: FinOps
  url: finops/finops.yml
- url: https://www.string-db.org/blog/
  type: Blog
- type: Website
  url: https://www.string-db.org/
- type: DomainSecurity
  url: security/string-db-domain-security.yml
- type: TermsOfService
  url: https://string-db.org/cgi/info?footer_active_subpage=cookies
- type: Licensing
  url: https://string-db.org/cgi/access?footer_active_subpage=licensing
- type: UsageGuidelines
  url: https://string-db.org/cgi/access?footer_active_subpage=usage
- type: APIDocumentation
  url: https://string-db.org/help/api/
- type: Downloads
  url: https://string-db.org/cgi/download
modified: '2026-10-06'
maintainers:
- FN: STRING Consortium
  url: https://string-db.org

STRING API — frequently asked questions

Does STRING have an API?

Yes. APIs.io lists 7 APIs from STRING, including STRING Annotation API, STRING Enrichment API and STRING Homology API, and 4 more.

Is there an OpenAPI specification for the STRING API?

Yes. APIs.io indexes 7 OpenAPI specifications for STRING, each linked for download from this page.

How do I authenticate with the STRING API?

STRING uses bearer-token authentication.

How much does the STRING API cost?

APIs.io lists 2 pricing plans for STRING, with each plan's price, limits and inclusions under Pricing on this page.

Does STRING have an MCP server?

Yes. APIs.io lists 1 MCP server for STRING: Remote MCP server at mcp.string-db.org over HTTP; 17 tools listed.

Is the STRING API ready for AI agents?

STRING has a Kin Score of 27.3 out of 100 (thin) and an Agent Readiness score of 28.7 (agent-ready), scored by API Evangelist on 2026-11-06.

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