STRING · Example Payload

Functional Enrichment

Example: Functional enrichment analysis for a set of human DNA damage response proteins

BioinformaticsProteinsGenomicsLife SciencesResearchOpen Data

Functional Enrichment is an example object payload from STRING, with 3 top-level fields. It illustrates the shape of data this provider's APIs accept or return.

Top-level fields

descriptionrequestresponse

Example Payload

{
  "description": "Example: Functional enrichment analysis for a set of human DNA damage response proteins",
  "request": {
    "method": "GET",
    "url": "https://string-db.org/api/json/enrichment",
    "parameters": {
      "identifiers": "9606.ENSP00000269305%0d9606.ENSP00000366955%0d9606.ENSP00000380152",
      "species": 9606,
      "caller_identity": "example_pipeline"
    }
  },
  "response": [
    {
      "category": "Process",
      "term": "GO:0006974",
      "number_of_genes": 3,
      "number_of_genes_in_background": 287,
      "ncbiTaxonId": 9606,
      "inputGenes": "9606.ENSP00000269305,9606.ENSP00000366955,9606.ENSP00000380152",
      "preferredNames": "TP53,ATM,BRCA1",
      "p_value": 1.23e-10,
      "fdr": 4.56e-8,
      "description": "cellular response to DNA damage stimulus"
    },
    {
      "category": "Process",
      "term": "GO:0006281",
      "number_of_genes": 3,
      "number_of_genes_in_background": 413,
      "ncbiTaxonId": 9606,
      "inputGenes": "9606.ENSP00000269305,9606.ENSP00000366955,9606.ENSP00000380152",
      "preferredNames": "TP53,ATM,BRCA1",
      "p_value": 2.87e-9,
      "fdr": 5.31e-7,
      "description": "DNA repair"
    },
    {
      "category": "KEGG",
      "term": "hsa04110",
      "number_of_genes": 2,
      "number_of_genes_in_background": 126,
      "ncbiTaxonId": 9606,
      "inputGenes": "9606.ENSP00000269305,9606.ENSP00000366955",
      "preferredNames": "TP53,ATM",
      "p_value": 3.45e-4,
      "fdr": 0.012,
      "description": "Cell cycle"
    }
  ]
}

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