Reactome

Reactome Search API

Reactome Search

GitHub OpenAPI

Operations 12

GET /search/diagram/{diagram} Performs a Solr query (diagram widget scoped) for a given QueryObject #
GET /search/diagram/{diagram}/occurrences/{instance} Performs a Solr query (diagram widget scoped) for a given QueryObject #
GET /search/diagram/{pathwayId}/flag A list of diagram entities plus pathways from the provided list containing the… #
GET /search/facet A list of facets corresponding to the whole Reactome search data #
GET /search/facet_query A list of facets corresponding to a specific query #
GET /search/fireworks Performs a Solr query (fireworks widget scoped) for a given QueryObject #
GET /search/fireworks/flag Performs a Solr query (fireworks widget scoped) for a given QueryObject #
GET /search/pathways/of/{dbId} Find the different pathways containing a specific entity determined by its dbId. #
GET /search/query Queries Solr against the Reactome knowledgebase #
GET /search/query/paginated Queries Solr against the Reactome knowledgebase #
GET /search/spellcheck Spell-check suggestions for a given query #
GET /search/suggest Auto-suggestions for a given query #

Documentation

📖
Documentation
https://reactome.org/dev/content-service
📖
Documentation
https://reactome.org/dev/analysis

Specifications

⚙
OpenAPI
https://raw.githubusercontent.com/api-evangelist/reactome/refs/heads/main/openapi/reactome-search-api-openapi.yml

Other Resources

🔗
SwaggerUI
https://reactome.org/ContentService/
🔗
SwaggerUI
https://reactome.org/AnalysisService/

Work with this as data

Every API here is available over the APIs.io API and to AI agents over MCP.

MCP server

One button, every client — Claude, Cursor, VS Code and the rest.

https://apis.io/mcp

Tools for apis

7 MCP tools reach this
  • find_apisBrowse and filter every API in the catalog.
  • get_api_artifactsOne API's artifacts, grouped by type.
  • get_openapiThe primary OpenAPI for this API.
  • find_similar_apisAPIs that look like this one.
  • apis_io_searchSTART HERE — APIs, providers and tags for one query, each with its total.
  • resolveTurn a domain, URL or GitHub org into the provider it belongs to.
  • find_cohortsEvery scored population of providers in the catalog.
All 92 tools →

Call it yourself

curl for this page
This API 
curl "https://apis.io/api/v1/apis/reactome-search-api"
All apis 
curl "https://apis.io/api/v1/apis?limit=25"

Discovery needs no key. Ratings and market analysis are Pro.

Get an API key

Free tier, no form to fill in. Signing in shares your email address with us — we store it to create your key and to recognise you if you sign in with another provider. See our Privacy Policy and Terms.

GitHub Google LinkedIn

A second provider on the same verified email joins the account you already have.

OpenAPI Specification

reactome-search-api-openapi.yml Raw ↑ 
openapi: 3.2.0
info:
  title: Content Service Search API
  description: REST API for Reactome content
  termsOfService: /license
  contact:
    name: Reactome
    url: https://reactome.org
    email: help@reactome.org
  license:
    name: Creative Commons Attribution 4.0 International (CC BY 4.0) License
    url: https://creativecommons.org/licenses/by/4.0/
  version: '1.2'
servers:
- url: /ContentService
tags:


# --- truncated at 32 KB (35 KB total) ---
# Full source: https://raw.githubusercontent.com/api-evangelist/reactome/refs/heads/main/openapi/reactome-search-api-openapi.yml