Aetna Realtime Pharmacy Benefit Check API

Consumer Real-Time Pharmacy Benefit Check 1.0.0, launched 2024-12-05, letting members and EHR systems retrieve prescription drug cost and coverage information at the point of prescribing. Built to satisfy California AB 2352 and Texas HB 0662H. Exposed as a FHIR messaging operation at /v1/realtimepharmacybenefitcheck/$process-message (member-facing) and /realtimepharmacybenefitcheck/v1/$process-message (provider-facing). Production traffic moved to the apix.cvshealth.com host on 2026-03-04. Spec documents returned HTTP 403 to this harvest.

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API entry from apis.yml

apis.yml Raw ↑
aid: aetna-realtime-pharmacy-benefit-check-api
name: Aetna Realtime Pharmacy Benefit Check API
description: Consumer Real-Time Pharmacy Benefit Check 1.0.0, launched 2024-12-05, letting members and
  EHR systems retrieve prescription drug cost and coverage information at the point of prescribing. Built
  to satisfy California AB 2352 and Texas HB 0662H. Exposed as a FHIR messaging operation at /v1/realtimepharmacybenefitcheck/$process-message
  (member-facing) and /realtimepharmacybenefitcheck/v1/$process-message (provider-facing). Production
  traffic moved to the apix.cvshealth.com host on 2026-03-04. Spec documents returned HTTP 403 to this
  harvest.
humanURL: https://developerportal.aetna.com/
baseURL: https://apix.cvshealth.com
tags:
- FHIR
- Pharmacy
- Real-Time Benefit Check
- RTPBC
- Prescription Cost
properties:
- type: Documentation
  url: https://developerportal.aetna.com/
- type: DeveloperPortal
  url: https://developerportal.aetna.com/
- type: APIReference
  url: https://developerportal.aetna.com/assets/Data/Fhir.json