Surescripts Medication History for Populations FHIR API

Publicly documented HL7 FHIR Release 4 API for retrieving medication history panels and near-real-time Prescription Notifications for enrolled patient populations. Panels and notifications are pulled with a FHIR search of the Communication resource (GET /ext/v1/Communication) and returned as a Bundle of Patient, Organization, Practitioner, MedicationRequest, MedicationDispense, Medication, Condition and Communication resources, with CapabilityStatement and OperationOutcome available. Authentication is mutual TLS with a Surescripts-issued client certificate plus mandatory X-SENDER-UID and X-SENDER-UID-QUALIFIER headers. The guide templates the host as https://FQDN/ext/v1; the base URL recorded here is the host that appears throughout the provider's own published request/response examples, and a live TLS probe on 2026-08-15 confirmed it serves a Surescripts-issued certificate for that name.

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API entry from apis.yml

apis.yml Raw ↑
aid: surescripts:surescripts-medication-history-populations-fhir-api
name: Surescripts Medication History for Populations FHIR API
tags:
- FHIR
- HL7 FHIR R4
- Medication History
- Care Coordination
- Prescription Notifications
image: https://kinlane-images.s3.amazonaws.com/shared/apis-json/apis-json-logo.jpg
humanURL: https://docs.surescripts.com/medhistory-populations/guide
baseURL: https://care-coordination.surescripts.net/ext/v1
endpointsModeled: false
properties:
- url: https://docs.surescripts.com/medhistory-populations/guide
  type: Documentation
- url: https://docs.surescripts.com/medhistory-populations/guide/medication-history-for-populations-element-details
  type: APIReference
- url: https://docs.surescripts.com/medhistory-populations/guide/request-and-response-examples
  type: Documentation
- url: https://docs.surescripts.com/medhistory-populations/guide/document-change-log
  type: ChangeLog
description: Publicly documented HL7 FHIR Release 4 API for retrieving medication history panels and near-real-time
  Prescription Notifications for enrolled patient populations. Panels and notifications are pulled with
  a FHIR search of the Communication resource (GET /ext/v1/Communication) and returned as a Bundle of
  Patient, Organization, Practitioner, MedicationRequest, MedicationDispense, Medication, Condition and
  Communication resources, with CapabilityStatement and OperationOutcome available. Authentication is
  mutual TLS with a Surescripts-issued client certificate plus mandatory X-SENDER-UID and X-SENDER-UID-QUALIFIER
  headers. The guide templates the host as https://FQDN/ext/v1; the base URL recorded here is the host
  that appears throughout the provider's own published request/response examples, and a live TLS probe
  on 2026-08-15 confirmed it serves a Surescripts-issued certificate for that name.