Reactome · Agentic Access

Reactome Agentic Access

x-agentic-access generated

Reactome exposes 122 API operations that an AI agent could call, of which 31 are state-changing ‘acting’ operations. This is a recommended x-agentic-access execution contract — the scope, audience, consequence tier, short-lived token constraints, and escalation each action should carry before it is handed to an autonomous agent.

By consequence: 91 read, 30 write, and 1 physical.

Contracts are classified heuristically from the provider’s OpenAPI and refresh on every APIs.io network build; audience is bound per deployment. The model follows Curity’s Access Intelligence (apidays Munich 2026). Browse every provider’s agent contracts at agentic-access.apis.io.

Biological PathwaysBioinformaticsLife SciencesPathway AnalysisGene EnrichmentMolecular InteractionsSystems BiologyOpen Science

Operations: 122 Acting: 31 Human-in-the-loop: 0 Method: generated

By consequence

read 91 write 30 physical 1

Highest-consequence actions

The physical and safety-critical operations an agent could invoke — the ones that most warrant scoped tokens, tight TTLs, and escalation. Full per-operation contracts are in the source below.

Method	Path	Consequence	Human-in-loop
POST	/interactors/upload/tuple/url	physical	conditional

Source

Agentic Access

generated: '2026-07-15'
method: generated
source: openapi/analysis-service.json, openapi/content-service.json
description: Recommended x-agentic-access execution contracts, classified heuristically from
  the OpenAPI. A governance starting point for exposing this API to AI agents — review and bind
  audience per deployment. See research/curity/agentic-governance/.
summary:
  operations: 122
  by_action_class:
    connected: 91
    acting: 31
  by_consequence:
    read: 91
    write: 30
    physical: 1
  human_in_the_loop_required: 0
operations:
- path: /database/name
  method: get
  operationId: getDBName
  x-agentic-access:
    action-class: connected
    consequence: read
    subject: optional
    token:
      max-ttl: 3600
    audit: none
- path: /database/version
  method: get
  operationId: getDBVersion
  x-agentic-access:
    action-class: connected
    consequence: read
    subject: optional
    token:
      max-ttl: 3600
    audit: none
- path: /download/{token}/entities/found/{resource}/{filename}.csv
  method: get
  operationId: downloadMappingResult
  x-agentic-access:
    action-class: connected
    consequence: read
    subject: optional
    token:
      max-ttl: 3600
    audit: none
- path: /download/{token}/entities/notfound/{filename}.csv
  method: get
  operationId: downloadNotFound
  x-agentic-access:
    action-class: connected
    consequence: read
    subject: optional
    token:
      max-ttl: 3600
    audit: none
- path: /download/{token}/pathways/{resource}/{filename}.csv
  method: get
  operationId: downloadResultCSV
  x-agentic-access:
    action-class: connected
    consequence: read
    subject: optional
    token:
      max-ttl: 3600
    audit: none
- path: /download/{token}/result.json
  method: get
  operationId: downloadResultJSON
  x-agentic-access:
    action-class: connected
    consequence: read
    subject: optional
    token:
      max-ttl: 3600
    audit: none
- path: /download/{token}/result.json.gz
  method: get
  operationId: downloadResultGZIP
  x-agentic-access:
    action-class: connected
    consequence: read
    subject: optional
    token:
      max-ttl: 3600
    audit: none
- path: /identifier/{id}
  method: get
  operationId: getIdentifier
  x-agentic-access:
    action-class: connected
    consequence: read
    subject: optional
    token:
      max-ttl: 3600
    audit: none
- path: /identifier/{id}/projection
  method: get
  operationId: getIdentifierToHuman
  x-agentic-access:
    action-class: connected
    consequence: read
    subject: optional
    token:
      max-ttl: 3600
    audit: none
- path: /identifiers/
  method: post
  operationId: getPostText_1
  x-agentic-access:
    action-class: acting
    consequence: write
    subject: required
    audience: null
    token:
      max-ttl: 900
    escalation:
      human-in-the-loop: conditional
      triggers:
      - abnormal
      - high-value
    audit: required
- path: /identifiers/form
  method: post
  operationId: getPostFile_1
  x-agentic-access:
    action-class: acting
    consequence: write
    subject: required
    audience: null
    token:
      max-ttl: 900
    escalation:
      human-in-the-loop: conditional
      triggers:
      - abnormal
      - high-value
    audit: required
- path: /identifiers/form/projection
  method: post
  operationId: getPostFileToHuman
  x-agentic-access:
    action-class: acting
    consequence: write
    subject: required
    audience: null
    token:
      max-ttl: 900
    escalation:
      human-in-the-loop: conditional
      triggers:
      - abnormal
      - high-value
    audit: required
- path: /identifiers/projection
  method: post
  operationId: getPostTextToHuman
  x-agentic-access:
    action-class: acting
    consequence: write
    subject: required
    audience: null
    token:
      max-ttl: 900
    escalation:
      human-in-the-loop: conditional
      triggers:
      - abnormal
      - high-value
    audit: required
- path: /identifiers/url
  method: post
  operationId: getPostURL_1
  x-agentic-access:
    action-class: acting
    consequence: write
    subject: required
    audience: null
    token:
      max-ttl: 900
    escalation:
      human-in-the-loop: conditional
      triggers:
      - abnormal
      - high-value
    audit: required
- path: /identifiers/url/projection
  method: post
  operationId: getPostURLToHuman
  x-agentic-access:
    action-class: acting
    consequence: write
    subject: required
    audience: null
    token:
      max-ttl: 900
    escalation:
      human-in-the-loop: conditional
      triggers:
      - abnormal
      - high-value
    audit: required
- path: /import/
  method: post
  operationId: getPostText
  x-agentic-access:
    action-class: acting
    consequence: write
    subject: required
    audience: null
    token:
      max-ttl: 900
    escalation:
      human-in-the-loop: conditional
      triggers:
      - abnormal
      - high-value
    audit: required
- path: /import/form
  method: post
  operationId: getPostFile
  x-agentic-access:
    action-class: acting
    consequence: write
    subject: required
    audience: null
    token:
      max-ttl: 900
    escalation:
      human-in-the-loop: conditional
      triggers:
      - abnormal
      - high-value
    audit: required
- path: /import/url
  method: post
  operationId: getPostURL
  x-agentic-access:
    action-class: acting
    consequence: write
    subject: required
    audience: null
    token:
      max-ttl: 900
    escalation:
      human-in-the-loop: conditional
      triggers:
      - abnormal
      - high-value
    audit: required
- path: /mapping/
  method: post
  operationId: getMapping
  x-agentic-access:
    action-class: acting
    consequence: write
    subject: required
    audience: null
    token:
      max-ttl: 900
    escalation:
      human-in-the-loop: conditional
      triggers:
      - abnormal
      - high-value
    audit: required
- path: /mapping/form
  method: post
  operationId: getMappingPostFile
  x-agentic-access:
    action-class: acting
    consequence: write
    subject: required
    audience: null
    token:
      max-ttl: 900
    escalation:
      human-in-the-loop: conditional
      triggers:
      - abnormal
      - high-value
    audit: required
- path: /mapping/form/projection
  method: post
  operationId: getMappingPostFileToHuman
  x-agentic-access:
    action-class: acting
    consequence: write
    subject: required
    audience: null
    token:
      max-ttl: 900
    escalation:
      human-in-the-loop: conditional
      triggers:
      - abnormal
      - high-value
    audit: required
- path: /mapping/projection
  method: post
  operationId: getMappingToHuman
  x-agentic-access:
    action-class: acting
    consequence: write
    subject: required
    audience: null
    token:
      max-ttl: 900
    escalation:
      human-in-the-loop: conditional
      triggers:
      - abnormal
      - high-value
    audit: required
- path: /mapping/url
  method: post
  operationId: getMappingPostURL
  x-agentic-access:
    action-class: acting
    consequence: write
    subject: required
    audience: null
    token:
      max-ttl: 900
    escalation:
      human-in-the-loop: conditional
      triggers:
      - abnormal
      - high-value
    audit: required
- path: /mapping/url/projection
  method: post
  operationId: getMappingPostURLToHuman
  x-agentic-access:
    action-class: acting
    consequence: write
    subject: required
    audience: null
    token:
      max-ttl: 900
    escalation:
      human-in-the-loop: conditional
      triggers:
      - abnormal
      - high-value
    audit: required
- path: /report/{token}/{species}/{filename}.pdf
  method: get
  operationId: generatePdfReport
  x-agentic-access:
    action-class: connected
    consequence: read
    subject: optional
    token:
      max-ttl: 3600
    audit: none
- path: /species/homoSapiens/{species}
  method: get
  operationId: compareHomoSapiensTo
  x-agentic-access:
    action-class: connected
    consequence: read
    subject: optional
    token:
      max-ttl: 3600
    audit: none
- path: /token/{token}
  method: get
  operationId: getToken
  x-agentic-access:
    action-class: connected
    consequence: read
    subject: optional
    token:
      max-ttl: 3600
    audit: none
- path: /token/{token}/filter/pathways
  method: post
  operationId: getTokenFilterPathways
  x-agentic-access:
    action-class: acting
    consequence: write
    subject: required
    audience: null
    token:
      max-ttl: 900
    escalation:
      human-in-the-loop: conditional
      triggers:
      - abnormal
      - high-value
    audit: required
- path: /token/{token}/filter/species/{species}
  method: get
  operationId: filterBySpecies
  x-agentic-access:
    action-class: connected
    consequence: read
    subject: optional
    token:
      max-ttl: 3600
    audit: none
- path: /token/{token}/found/all
  method: post
  operationId: getTokenHitEntitiesPathways
  x-agentic-access:
    action-class: acting
    consequence: write
    subject: required
    audience: null
    token:
      max-ttl: 900
    escalation:
      human-in-the-loop: conditional
      triggers:
      - abnormal
      - high-value
    audit: required
- path: /token/{token}/found/all/{pathway}
  method: get
  operationId: getTokenHitEntitiesPathway
  x-agentic-access:
    action-class: connected
    consequence: read
    subject: optional
    token:
      max-ttl: 3600
    audit: none
- path: /token/{token}/found/entities/{pathway}
  method: get
  operationId: getTokenIdentifiersPathway
  x-agentic-access:
    action-class: connected
    consequence: read
    subject: optional
    token:
      max-ttl: 3600
    audit: none
- path: /token/{token}/found/interactors/{pathway}
  method: get
  operationId: getTokenInteractorsPathway
  x-agentic-access:
    action-class: connected
    consequence: read
    subject: optional
    token:
      max-ttl: 3600
    audit: none
- path: /token/{token}/notFound
  method: get
  operationId: getNotFoundIdentifiers
  x-agentic-access:
    action-class: connected
    consequence: read
    subject: optional
    token:
      max-ttl: 3600
    audit: none
- path: /token/{token}/page/{pathway}
  method: get
  operationId: getPageOfPathway
  x-agentic-access:
    action-class: connected
    consequence: read
    subject: optional
    token:
      max-ttl: 3600
    audit: none
- path: /token/{token}/pathways/binned
  method: get
  operationId: getPathwaysBinnedBySize
  x-agentic-access:
    action-class: connected
    consequence: read
    subject: optional
    token:
      max-ttl: 3600
    audit: none
- path: /token/{token}/reactions/pathways
  method: post
  operationId: getTokenFilterPathwaysReactions
  x-agentic-access:
    action-class: acting
    consequence: write
    subject: required
    audience: null
    token:
      max-ttl: 900
    escalation:
      human-in-the-loop: conditional
      triggers:
      - abnormal
      - high-value
    audit: required
- path: /token/{token}/reactions/{pathway}
  method: get
  operationId: getTokenFilterPathwayReactions
  x-agentic-access:
    action-class: connected
    consequence: read
    subject: optional
    token:
      max-ttl: 3600
    audit: none
- path: /token/{token}/resources
  method: get
  operationId: getResources
  x-agentic-access:
    action-class: connected
    consequence: read
    subject: optional
    token:
      max-ttl: 3600
    audit: none
- path: /data/complex/{id}/subunits
  method: get
  operationId: getComplexSubunits
  x-agentic-access:
    action-class: connected
    consequence: read
    subject: optional
    token:
      max-ttl: 3600
    audit: none
- path: /data/complexes/{resource}/{identifier}
  method: get
  operationId: getComplexesFor
  x-agentic-access:
    action-class: connected
    consequence: read
    subject: optional
    token:
      max-ttl: 3600
    audit: none
- path: /data/database/name
  method: get
  operationId: getDBName
  x-agentic-access:
    action-class: connected
    consequence: read
    subject: optional
    token:
      max-ttl: 3600
    audit: none
- path: /data/database/version
  method: get
  operationId: getDBVersion
  x-agentic-access:
    action-class: connected
    consequence: read
    subject: optional
    token:
      max-ttl: 3600
    audit: none
- path: /data/discover/{identifier}
  method: get
  operationId: eventDiscovery
  x-agentic-access:
    action-class: connected
    consequence: read
    subject: optional
    token:
      max-ttl: 3600
    audit: none
- path: /data/diseases
  method: get
  operationId: getDiseases
  x-agentic-access:
    action-class: connected
    consequence: read
    subject: optional
    token:
      max-ttl: 3600
    audit: none
- path: /data/diseases/doid
  method: get
  operationId: getDiseasesSummary
  x-agentic-access:
    action-class: connected
    consequence: read
    subject: optional
    token:
      max-ttl: 3600
    audit: none
- path: /data/entity/{id}/componentOf
  method: get
  operationId: getComponentsOf
  x-agentic-access:
    action-class: connected
    consequence: read
    subject: optional
    token:
      max-ttl: 3600
    audit: none
- path: /data/entity/{id}/in-depth
  method: get
  operationId: getPhysicalEntityInDepth
  x-agentic-access:
    action-class: connected
    consequence: read
    subject: optional
    token:
      max-ttl: 3600
    audit: none
- path: /data/entity/{id}/otherForms
  method: get
  operationId: getOtherFormsOf
  x-agentic-access:
    action-class: connected
    consequence: read
    subject: optional
    token:
      max-ttl: 3600
    audit: none
- path: /data/event/{id}/ancestors
  method: get
  operationId: getEventAncestors
  x-agentic-access:
    action-class: connected
    consequence: read
    subject: optional
    token:
      max-ttl: 3600
    audit: none
- path: /data/event/{id}/in-depth
  method: get
  operationId: getEventInDepth
  x-agentic-access:
    action-class: connected
    consequence: read
    subject: optional
    token:
      max-ttl: 3600
    audit: none
- path: /data/eventsHierarchy/{species}
  method: get
  operationId: getEventHierarchy
  x-agentic-access:
    action-class: connected
    consequence: read
    subject: optional
    token:
      max-ttl: 3600
    audit: none
- path: /data/mapping/{resource}/{identifier}/pathways
  method: get
  operationId: getPathways
  x-agentic-access:
    action-class: connected
    consequence: read
    subject: optional
    token:
      max-ttl: 3600
    audit: none
- path: /data/mapping/{resource}/{identifier}/reactions
  method: get
  operationId: getReactionsLikeEvent
  x-agentic-access:
    action-class: connected
    consequence: read
    subject: optional
    token:
      max-ttl: 3600
    audit: none
- path: /data/orthologies/ids/species/{speciesId}
  method: post
  operationId: getOrthologies
  x-agentic-access:
    action-class: acting
    consequence: write
    subject: required
    audience: null
    token:
      max-ttl: 900
    escalation:
      human-in-the-loop: conditional
      triggers:
      - abnormal
      - high-value
    audit: required
- path: /data/orthology/{id}/species/{speciesId}
  method: get
  operationId: getOrthology
  x-agentic-access:
    action-class: connected
    consequence: read
    subject: optional
    token:
      max-ttl: 3600
    audit: none
- path: /data/participants/{id}
  method: get
  operationId: getParticipants
  x-agentic-access:
    action-class: connected
    consequence: read
    subject: optional
    token:
      max-ttl: 3600
    audit: none
- path: /data/participants/{id}/participatingPhysicalEntities
  method: get
  operationId: getParticipatingPhysicalEntities
  x-agentic-access:
    action-class: connected
    consequence: read
    subject: optional
    token:
      max-ttl: 3600
    audit: none
- path: /data/participants/{id}/referenceEntities
  method: get
  operationId: getParticipatingReferenceEntities
  x-agentic-access:
    action-class: connected
    consequence: read
    subject: optional
    token:
      max-ttl: 3600
    audit: none
- path: /data/pathway/{id}/containedEvents
  method: get
  operationId: getContainedEvents
  x-agentic-access:
    action-class: connected
    consequence: read
    subject: optional
    token:
      max-ttl: 3600
    audit: none
- path: /data/pathway/{id}/containedEvents/{attributeName}
  method: get
  operationId: getContainedEvents_1
  x-agentic-access:
    action-class: connected
    consequence: read
    subject: optional
    token:
      max-ttl: 3600
    audit: none
- path: /data/pathways/low/diagram/entity/{id}
  method: get
  operationId: getPathwaysWithDiagramFor
  x-agentic-access:
    action-class: connected
    consequence: read
    subject: optional
    token:
      max-ttl: 3600
    audit: none
- path: /data/pathways/low/diagram/entity/{id}/allForms
  method: get
  operationId: getPathwaysWithDiagramForAllFormsOf
  x-agentic-access:
    action-class: connected
    consequence: read
    subject: optional
    token:
      max-ttl: 3600
    audit: none
- path: /data/pathways/low/entity/{id}
  method: get
  operationId: getPathwaysFor
  x-agentic-access:
    action-class: connected
    consequence: read
    subject: optional
    token:
      max-ttl: 3600
    audit: none
- path: /data/pathways/low/entity/{id}/allForms
  method: get
  operationId: getPathwaysForAllFormsOf
  x-agentic-access:
    action-class: connected
    consequence: read
    subject: optional
    token:
      max-ttl: 3600
    audit: none
- path: /data/pathways/top/{species}
  method: get
  operationId: getTopLevelPathways
  x-agentic-access:
    action-class: connected
    consequence: read
    subject: optional
    token:
      max-ttl: 3600
    audit: none
- path: /data/people/name/{name}
  method: get
  operationId: queryPersonByName
  x-agentic-access:
    action-class: connected
    consequence: read
    subject: optional
    token:
      max-ttl: 3600
    audit: none
- path: /data/people/name/{name}/exact
  method: get
  operationId: findPersonByName
  x-agentic-access:
    action-class: connected
    consequence: read
    subject: optional
    token:
      max-ttl: 3600
    audit: none
- path: /data/person/{id}
  method: get
  operationId: findPerson
  x-agentic-access:
    action-class: connected
    consequence: read
    subject: optional
    token:
      max-ttl: 3600
    audit: none
- path: /data/person/{id}/authoredPathways
  method: get
  operationId: getAuthoredPathways
  x-agentic-access:
    action-class: connected
    consequence: read
    subject: optional
    token:
      max-ttl: 3600
    audit: none
- path: /data/person/{id}/publications
  method: get
  operationId: getPublicationsOfPerson
  x-agentic-access:
    action-class: connected
    consequence: read
    subject: optional
    token:
      max-ttl: 3600
    audit: none
- path: /data/person/{id}/{attributeName}
  method: get
  operationId: findPerson_1
  x-agentic-access:
    action-class: connected
    consequence: read
    subject: optional
    token:
      max-ttl: 3600
    audit: none
- path: /data/query/enhanced/v2/{id}
  method: get
  operationId: findEnhancedObjectById
  x-agentic-access:
    action-class: connected
    consequence: read
    subject: optional
    token:
      max-ttl: 3600
    audit: none
- path: /data/query/enhanced/{id}
  method: get
  operationId: findOldEnhancedObjectById
  x-agentic-access:
    action-class: connected
    consequence: read
    subject: optional
    token:
      max-ttl: 3600
    audit: none
- path: /data/query/ids
  method: post
  operationId: findByIds
  x-agentic-access:
    action-class: acting
    consequence: write
    subject: required
    audience: null
    token:
      max-ttl: 900
    escalation:
      human-in-the-loop: conditional
      triggers:
      - abnormal
      - high-value
    audit: required
- path: /data/query/ids/map
  method: post
  operationId: findByIdsMap
  x-agentic-access:
    action-class: acting
    consequence: write
    subject: required
    audience: null
    token:
      max-ttl: 900
    escalation:
      human-in-the-loop: conditional
      triggers:
      - abnormal
      - high-value
    audit: required
- path: /data/query/{id}
  method: get
  operationId: findById
  x-agentic-access:
    action-class: connected
    consequence: read
    subject: optional
    token:
      max-ttl: 3600
    audit: none
- path: /data/query/{id}/{attributeName}
  method: get
  operationId: findById_1
  x-agentic-access:
    action-class: connected
    consequence: read
    subject: optional
    token:
      max-ttl: 3600
    audit: none
- path: /data/schema/model
  method: get
  operationId: getSchemaModel
  x-agentic-access:
    action-class: connected
    consequence: read
    subject: optional
    token:
      max-ttl: 3600
    audit: none
- path: /data/schema/{className}
  method: get
  operationId: getDatabaseObjectsForClassName
  x-agentic-access:
    action-class: connected
    consequence: read
    subject: optional
    token:
      max-ttl: 3600
    audit: none
- path: /data/schema/{className}/count
  method: get
  operationId: countEntries
  x-agentic-access:
    action-class: connected
    consequence: read
    subject: optional
    token:
      max-ttl: 3600
    audit: none
- path: /data/schema/{className}/min
  method: get
  operationId: getSimpleDatabaseObjectByClassName
  x-agentic-access:
    action-class: connected
    consequence: read
    subject: optional
    token:
      max-ttl: 3600
    audit: none
- path: /data/schema/{className}/reference
  method: get
  operationId: getSimpleReferencesObjectsByClassName
  x-agentic-access:
    action-class: connected
    consequence: read
    subject: optional
    token:
      max-ttl: 3600
    audit: none
- path: /data/species/all
  method: get
  operationId: getAllSpecies
  x-agentic-access:
    action-class: connected
    consequence: read
    subject: optional
    token:
      max-ttl: 3600
    audit: none
- path: /data/species/main
  method: get
  operationId: getSpecies
  x-agentic-access:
    action-class: connected
    consequence: read
    subject: optional
    token:
      max-ttl: 3600
    audit: none
- path: /exporter/diagram/{identifier}.{ext}
  method: get
  operationId: diagramImage_1
  x-agentic-access:
    action-class: connected
    consequence: read
    subject: optional
    token:
      max-ttl: 3600
    audit: none
- path: /exporter/document/event/{identifier}.pdf
  method: get
  operationId: eventPdf
  x-agentic-access:
    action-class: connected
    consequence: read
    subject: optional
    token:
      max-ttl: 3600
    audit: none
- path: /exporter/event/{identifier}.sbgn
  method: get
  operationId: eventSBGN
  x-agentic-access:
    action-class: connected
    consequence: read
    subject: optional
    token:
      max-ttl: 3600
    audit: none
- path: /exporter/event/{identifier}.sbml
  method: get
  operationId: eventSBML
  x-agentic-access:
    action-class: connected
    consequence: read
    subject: optional
    token:
      max-ttl: 3600
    audit: none
- path: /exporter/fireworks/{species}.{ext}
  method: get
  operationId: diagramImage
  x-agentic-access:
    action-class: connected
    consequence: read
    subject: optional
    token:
      max-ttl: 3600
    audit: none
- path: /exporter/reaction/{identifier}.{ext}
  method: get
  operationId: reactionImage
  x-agentic-access:
    action-class: connected
    consequence: read
    subject: optional
    token:
      max-ttl: 3600
    audit: none
- path: /interactors/psicquic/molecule/{resource}/{acc}/details
  method: get
  operationId: getProteinDetailsByResource
  x-agentic-access:
    action-class: connected
    consequence: read
    subject: optional
    token:
      max-ttl: 3600
    audit: none
- path: /interactors/psicquic/molecule/{resource}/{acc}/summary
  method: get
  operationId: getProteinSummaryByResource
  x-agentic-access:
    action-class: connected
    consequence: read
    subject: optional
    token:
      max-ttl: 3600
    audit: none
- path: /interactors/psicquic/molecules/{resource}/details
  method: post
  operationId: getProteinsDetailsByResource
  x-agentic-access:
    action-class: acting
    consequence: write
    subject: required
    audience: null
    token:
      max-ttl: 900
    escalation:
      human-in-the-loop: conditional
      triggers:
      - abnormal
      - high-value
    audit: required
- path: /interactors/psicquic/molecules/{resource}/summary
  method: post
  operationId: getProteinsSummaryByResource
  x-agentic-access:
    action-class: acting
    consequence: write
    subject: required
    audience: null
    token:
      max-ttl: 900
    escalation:
      human-in-the-loop: conditional
      triggers:
      - abnormal
      - high-value
    audit: required
- path: /interactors/psicquic/resources
  method: get
  operationId: getResources
  x-agentic-access:
    action-class: connected
    consequence: read
    subject: optional
    token:
      max-ttl: 3600
    audit: none
- path: /interactors/static/molecule/enhanced/{acc}/details
  method: get
  operationId: getCustomInteractionsByAcc
  x-agentic-access:
    action-class: connected
    consequence: read
    subject: optional
    token:
      max-ttl: 3600
    audit: none
- path: /interactors/static/molecule/{acc}/details
  method: get
  operationId: getProteinDetailsByAcc
  x-agentic-access:
    action-class: connected
    consequence: read
    subject: optional
    token:
      max-ttl: 3600
    audit: none
- path: /interactors/static/molecule/{acc}/pathways
  method: get
  operationId: getLowerLevelPathways
  x-agentic-access:
    action-class: connected
    consequence: read
    subject: optional
    token:
      max-ttl: 3600
    audit: none
- path: /interactors/static/molecule/{acc}/summary
  method: get
  operationId: getProteinSummaryByAcc
  x-agentic-access:
    action-class: connected
    consequence: read
    subject: optional
    token:
      max-ttl: 3600
    audit: none
- path: /interactors/static/molecules/details
  method: post
  operationId: getProteinsDetailsByAccs
  x-agentic-access:
    action-class: acting
    consequence: write
    subject: required
    audience: null
    token:
      max-ttl: 900
    escalation:
      human-in-the-loop: conditional
      triggers:
      - abnormal
      - high-value
    audit: required
- path: /interactors/static/molecules/summary
  method: post
  operationId: getProteinsSummaryByAccs
  x-agentic-access:
    action-class: acting
    consequence: write
    subject: required
    audience: null
    token:
      max-ttl: 900
    escalation:
      human-in-the-loop: conditional
      triggers:
      - abnormal
      - high-value
    audit: required
- path: /interactors/token/{token}
  method: post
  operationId: getInteractors
  x-agentic-access:
    action-class: acting
    consequence: write
    subject: required
    audience: null
    token:
      max-ttl: 900
    escalation:
      human-in-the-loop: conditional
      triggers:
      - abnormal
      - high-value
    audit: required
- path: /interactors/upload/psicquic/url
  method: post
  operationId: registryPsicquicURL
  x-agentic-access:
    action-class: acting
    consequence: write
    subject: required
    audience: null
    token:
      max-ttl: 900
    escalation:
      human-in-the-loop: conditional
      triggers:
      - abnormal
      - high-value
    audit: required
- path: /interactors/upload/tuple/content
  method: post
  operationId: postFileContent
  x-agentic-access:
    action-class: acting
    consequence: write
    subject: required
    audience: null
    token:
      max-ttl: 900
    escalation:
      human-in-the-loop: conditional
      triggers:
      - abnormal
      - high-value
    audit: required
- path: /interactors/upload/tuple/form
  method: post
  operationId: postFile
  x-agentic-access:
    action-class: acting
    consequence: write
    subject: required
    audience: null
    token:
      max-ttl: 900
    escalation:
      human-in-the-loop: conditional
      triggers:
      - abnormal
      - high-value
    audit: required
- path: /interactors/upload/tuple/url
  method: post
  operationId: postUrl
  x-agentic-access:
    action-class: acting
    consequence: physical
    subject: required
    audience: null
    token:
      max-ttl: 300
      exchange: true
      purpose-required: true
    escalation:
      human-in-the-loop: conditional
      triggers:
      - abnormal
      - high-value
    audit: required
- path: /references/mapping/xrefs
  method: post
  operationId: getCrossReferencesForList
  x-agentic-access:
    action-class: acting
    consequence: write
    subject: required
    audience: null
    token:
      max-ttl: 900
    escalation:
      human-in-the-loop: conditional
      triggers:
      - abnormal
      - high-value
    audit: required
- path: /references/mapping/{identifier}
  method: get
  operationId: getReferenceEntitiesFor
  x-agentic-access:
    action-class: connected
    consequence: read
    subject: optional
    token:
      max-ttl: 3600
    audit: none
- path: /references/mapping/{identifier}/xrefs
  method: get
  operationId: getCrossReferencesFor
  x-agentic-access:
    action-class: connected
    consequence: read
    subject: optional
    token:
      max-ttl: 3600
    audit: none
- path: /search/diagram/{diagram}
  method: get
  operationId: getDiagramResult
  x-agentic-access:
    action-class: connected
    consequence: read
    subject: optional
    token:
      max-ttl: 3600
    audit: none
- path: /search/diagram/{diagram}/occurrences/{instance}
  method: get
  operationId: getDiagramOccurrences
  x-agentic-access:
    action-class: connected
    consequence: read
    subject: optional
    token:
      max-ttl: 3600
    audit: none
- path: /search/diagram/{pathwayId}/flag
  method: get
  operationId: getEntitiesInDiagramForIdentifier
  x-agentic-access:
    action-class: connected
    consequence: read
    subject: optional
    token:
      max-ttl: 3600
    audit: none
- path: /search/facet
  method: get
  operationId: facet
  x-agentic-access:
    action-class: connected
    consequence: read
    subject: optional
    token:
      max-ttl: 3600
    audit: none
- path: /search/facet_query
  method: get
  operationId: facet_type
  x-agentic-access:
    action-class: connected
    consequence: read
    subject: optional
    token:
      max-ttl: 3600
    audit: none
- path: /search/fireworks
  method: get
  operationId: getFireworksResult
  x-agentic-access:
    action-class: connected
    consequence: read
    subject: optional
    token:
      max-ttl: 3600
    audit: none
- path: /search/fireworks/flag
  method: get
  operationId: fireworksFlagging
  x-agentic-access:
    action-class: connected
    consequence: read
    subject: optional
    token:
      max-ttl: 3600
    audit: none
- path: /search/pathways/of/{dbId}
  method: get
  operationId: getContainingPathwaysOf
  x-agentic-access:
    action-class: connected
    consequence: read
    subject: optional
    token:
      max-ttl: 3600
    audit: none
- path: /search/query
  method: get
  operationId: getSearchResult
  x-agentic-access:
    action-class: connected
    consequence: read
    subject: optional
    token:
      max-ttl: 3600
    audit: none
- path: /search/query/paginated
  method: get
  operationId: getResult
  x-agentic-access:
    action-class: connected
    consequence: read
    subject: optional
    token:
      max-ttl: 3600
    audit: none
- path: /search/spellcheck
  method: get
  operationId: spellcheckerSuggestions
  x-agentic-access:
    action-class: connected
    consequence: read
    subject: optional
    token:
      max-ttl: 3600
    audit: none
- path: /search/suggest
  method: get
  operationId: suggesterSuggestions
  x-agentic-access:
    action-class: connected
    consequence: read
    subject: optional
    token:
      max-ttl: 3600
    audit: none

Work with this as data

Every access contract here is available over the APIs.io API and to AI agents over MCP. Agentic Access is not yet its own endpoint on the v1 API. Reach it through catalog search and the tag graph, or the MCP server.

MCP server

One button, every client — Claude, Cursor, VS Code and the rest.

https://apis.io/mcp

Tools for agentic access

3 MCP tools reach this

apis_io_searchSTART HERE — APIs, providers and tags for one query, each with its total.
resolveTurn a domain, URL or GitHub org into the provider it belongs to.
find_cohortsEvery scored population of providers in the catalog.

All 92 tools →

Call it yourself

curl for this page

Search the catalog

curl "https://apis.io/api/v1/search?q=reactome-agentic-access&limit=10"

Everything under a tag

curl "https://apis.io/api/v1/tags/reactome-agentic-access"

Discovery needs no key. Ratings and market analysis are Pro.

Get an API key

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A second provider on the same verified email joins the account you already have.