Surescripts · Authentication Profile
Surescripts Authentication
Authentication
Surescripts secures its APIs with mutualTLS and apiKey across 4 declared security schemes, as derived from its OpenAPI definitions.
Healthcaree-PrescribingHealth Information NetworkNCPDP SCRIPTMedication HistoryPrior AuthorizationInteroperabilityFHIRFormularyEligibilityReal-Time Prescription BenefitMutual TLSGated
Methods: mutualTLS, apiKey
Schemes: 4
OAuth flows:
API key in: header
Security Schemes
mutualTLS mutualTLS
x-participant-id apiKey
· in: header ()
X-SENDER-UID apiKey
· in: header ()
X-SENDER-UID-QUALIFIER apiKey
· in: header ()
Source
Authentication Profile
generated: '2026-08-15'
method: searched
source: https://docs.surescripts.com/formulary-download/guide/security-and-data-access
docs:
- https://docs.surescripts.com/formulary-download/guide/security-and-data-access
- https://docs.surescripts.com/medhistory-populations/guide/http-request-headers
- https://docs.surescripts.com/medhistory-populations/guide/integration-and-production
- https://docs.surescripts.com/connectivity/home
- https://surescripts.com/why-surescripts/certifications-and-accreditations
note: >-
Derived by reading the public pages of the Surescripts Developer Portal
(docs.surescripts.com), not from an OpenAPI - Surescripts publishes no machine-readable
contract. Surescripts does not use OAuth, OIDC or bearer API keys anywhere in its public
documentation. Every documented API surface authenticates the CALLING ORGANIZATION with a
Surescripts-issued client certificate over mutual TLS, then authorizes the request with a
Participant ID carried in an HTTP header. Surescripts operates its own Certificate
Authority and Registration Authority (see the Surescripts Certification Practice Statement
on the certifications page), which is why its API hosts present a private-root chain.
summary:
types:
- mutualTLS
- apiKey
api_key_in:
- header
oauth2_flows: []
oauth2: false
openid_connect: false
bearer_tokens: false
self_serve_credentials: false
schemes:
- name: mutualTLS
type: mutualTLS
description: >-
Client certificate issued by the Surescripts Certification Authority, presented on
every request. Surescripts validates the certificate and resolves it to an Account ID
and Participant ID, which determine product entitlement and data access.
issued_by: Surescripts Issuing Certification Authority
self_serve: false
obtained_via: Surescripts onboarding / certification process
sources:
- https://docs.surescripts.com/formulary-download/guide/security-and-data-access
- https://docs.surescripts.com/medhistory-populations/guide/integration-and-production
evidence:
- >-
Formulary Download API: "restricts content based on the account of the user accessing
the system - identified by the MTLS client certificate submitted in the request"
- >-
Medication History for Populations: "For authentication, requests will use mTLS where
the client will provide a client certificate"
- >-
Live probe 2026-08-15: care-coordination.surescripts.net presents a leaf cert issued by
"Surescripts Issuing Certification Authority" chaining to "Surescripts Root Certification
Authority"; an anonymous request is reset before any HTTP response.
- name: x-participant-id
type: apiKey
in: header
parameter_name: x-participant-id
required: true
applies_to: Formulary Download API
description: >-
Participant ID of the requesting organization. Used together with the mTLS client
certificate to determine the NCPDP Formulary & Benefit version(s) available, the
preferred drug database, and per-file permission restrictions.
sources:
- https://docs.surescripts.com/formulary-download/guide/api-details
- https://docs.surescripts.com/formulary-download/guide/security-and-data-access
- name: X-SENDER-UID
type: apiKey
in: header
parameter_name: X-SENDER-UID
required: true
applies_to: Medication History for Populations FHIR API
description: >-
Participant ID of the sender, e.g. T00000000012345 (the leading T denotes a staging /
test participant). Accompanied by the mandatory X-SENDER-UID-QUALIFIER header, fixed
value 10.
sources:
- https://docs.surescripts.com/medhistory-populations/guide/http-request-headers
- name: X-SENDER-UID-QUALIFIER
type: apiKey
in: header
parameter_name: X-SENDER-UID-QUALIFIER
required: true
fixed_value: '10'
applies_to: Medication History for Populations FHIR API
sources:
- https://docs.surescripts.com/medhistory-populations/guide/http-request-headers
authorization:
model: participant-entitlement
description: >-
Authorization is not scope-based. Entitlement is configured by Surescripts per Participant
ID during onboarding: which products the participant may call, which NCPDP F&B versions it
may read, and which files/resource IDs it may retrieve. A request that is authenticated but
not entitled returns 403 (Formulary Download 403-01/403-02/403-03; FHIR "Product is not set
up for this participant ID").
failure_modes:
- condition: No client certificate presented
result: SSL Connect Error (connection reset; no HTTP status)
remediation: Include the Surescripts-issued client certificate
- condition: Certificate issuer or subject does not match the configured certificate
result: 401 Unauthorized
- condition: Certificate valid but participant not entitled to the product or resource
result: 403 Forbidden
identity_proofing:
required: true
note: >-
Identity Proofing Requirements and (for EPCS) a DEA third-party audit are pre-production
network requirements documented in the Connectivity and Operations section of the portal.
Those specific guides sit behind the portal's magic-link gate.
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