Properties
| Name | Type | Description |
|---|---|---|
| gene_id | string | |
| section | string | |
| status | string | |
| coverage | string | |
| coverage_scope | string | |
| freshness | object | |
| source_ids | array | |
| data | object | |
| limitations | array | |
| request_id | string | |
| snapshot_id | string | |
| pagination | object |
JSON Schema
{
"$schema": "https://json-schema.org/draft/2020-12/schema",
"$id": "https://artifacts.apis.io/helena-bio/json-schema/helena-bio-section-response-schema.json",
"title": "SectionResponse",
"x-generated": "2026-10-29",
"x-method": "derived",
"x-generator": "derive-json-schema.py",
"x-source": "openapi/helena-bio-openapi.json#/components/schemas/SectionResponse",
"properties": {
"gene_id": {
"type": "string",
"pattern": "^HGNC:[1-9][0-9]*$",
"title": "Gene Id"
},
"section": {
"type": "string",
"enum": [
"overview",
"disease_validity",
"structure",
"constraint",
"dosage",
"mechanisms",
"clinical_variants",
"clinical_variant_consequences",
"expression",
"gwas",
"phenotypes",
"protein_pathways",
"literature"
],
"title": "Section"
},
"status": {
"type": "string",
"enum": [
"available",
"source_has_no_record",
"unavailable",
"not_integrated",
"not_applicable"
],
"title": "Status"
},
"coverage": {
"type": "string",
"enum": [
"complete",
"partial",
"truncated",
"unknown"
],
"title": "Coverage"
},
"coverage_scope": {
"type": "string",
"maxLength": 2000,
"minLength": 1,
"title": "Coverage Scope"
},
"freshness": {
"$ref": "#/$defs/Freshness"
},
"source_ids": {
"items": {
"type": "string",
"maxLength": 200,
"minLength": 1
},
"type": "array",
"maxItems": 50,
"title": "Source Ids"
},
"data": {
"anyOf": [
{
"oneOf": [
{
"$ref": "#/$defs/OverviewData"
},
{
"$ref": "#/$defs/DiseaseData"
},
{
"$ref": "#/$defs/StructureData"
},
{
"$ref": "#/$defs/ConstraintData"
},
{
"$ref": "#/$defs/DosageData"
},
{
"$ref": "#/$defs/MechanismsData"
},
{
"$ref": "#/$defs/ClinicalVariantsData"
},
{
"$ref": "#/$defs/ClinicalConsequencesData"
},
{
"$ref": "#/$defs/ExpressionData"
},
{
"$ref": "#/$defs/GwasData"
},
{
"$ref": "#/$defs/PhenotypesData"
},
{
"$ref": "#/$defs/ProteinPathwaysData"
}
]
},
{
"type": "null"
}
],
"title": "Data"
},
"limitations": {
"items": {
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"minLength": 1
},
"type": "array",
"maxItems": 30,
"title": "Limitations"
},
"request_id": {
"type": "string",
"pattern": "^[A-Za-z0-9_-]{1,64}$",
"title": "Request Id"
},
"snapshot_id": {
"type": "string",
"pattern": "^[a-f0-9]{64}$",
"title": "Snapshot Id"
},
"pagination": {
"anyOf": [
{
"$ref": "#/$defs/variant_analysis_service__presentation__schemas__public_gene_schemas__Pagination"
},
{
"type": "null"
}
]
}
},
"additionalProperties": false,
"type": "object",
"required": [
"gene_id",
"section",
"status",
"coverage",
"coverage_scope",
"freshness",
"source_ids",
"data",
"limitations",
"request_id",
"snapshot_id",
"pagination"
],
"$defs": {
"ClinicalAxis": {
"properties": {
"axis": {
"type": "string",
"enum": [
"germline",
"somatic_clinical_impact",
"oncogenicity"
],
"title": "Axis"
},
"represented_variations": {
"type": "integer",
"minimum": 0.0,
"title": "Represented Variations"
},
"classification_counts": {
"items": {
"$ref": "#/$defs/DistributionBin"
},
"type": "array",
"maxItems": 1000,
"title": "Classification Counts"
},
"review_status_counts": {
"items": {
"$ref": "#/$defs/DistributionBin"
},
"type": "array",
"maxItems": 1000,
"title": "Review Status Counts"
}
},
"additionalProperties": false,
"type": "object",
"required": [
"axis",
"represented_variations",
"classification_counts",
"review_status_counts"
],
"title": "ClinicalAxis"
},
"ClinicalConsequenceRecord": {
"properties": {
"source_id": {
"type": "string",
"maxLength": 200,
"minLength": 1,
"title": "Source Id"
},
"so_id": {
"type": "string",
"pattern": "^SO:[0-9]{7}$",
"title": "So Id"
},
"term": {
"type": "string",
"maxLength": 2000,
"minLength": 1,
"title": "Term"
},
"represented_variations": {
"type": "integer",
"minimum": 1.0,
"title": "Represented Variations"
},
"axes": {
"items": {
"$ref": "#/$defs/ClinicalAxis"
},
"type": "array",
"maxItems": 3,
"minItems": 3,
"title": "Axes"
}
},
"additionalProperties": false,
"type": "object",
"required": [
"source_id",
"so_id",
"term",
"represented_variations",
"axes"
],
"title": "ClinicalConsequenceRecord"
},
"ClinicalConsequencesData": {
"properties": {
"kind": {
"type": "string",
"const": "clinical_variant_consequences",
"title": "Kind"
},
"source_id": {
"type": "string",
"maxLength": 200,
"minLength": 1,
"title": "Source Id"
},
"count_unit": {
"type": "string",
"const": "source_consequence_bin",
"title": "Count Unit",
"default": "source_consequence_bin"
},
"eligible_variations": {
"type": "integer",
"minimum": 0.0,
"title": "Eligible Variations"
},
"membership_rule": {
"type": "string",
"const": "single_native_geneinfo_unique_ncbi_crosswalk",
"title": "Membership Rule"
},
"consequence_scope": {
"type": "string",
"const": "provider_transcript_collapsed_MC",
"title": "Consequence Scope"
},
"records": {
"items": {
"$ref": "#/$defs/ClinicalConsequenceRecord"
},
"type": "array",
"maxItems": 1000,
"title": "Records"
}
},
"additionalProperties": false,
"type": "object",
"required": [
"kind",
"source_id",
"eligible_variations",
"membership_rule",
"consequence_scope",
"records"
],
"title": "ClinicalConsequencesData"
},
"ClinicalVariantExample": {
"properties": {
"source_id": {
"type": "string",
"maxLength": 200,
"minLength": 1,
"title": "Source Id"
},
"variation_id": {
"type": "string",
"pattern": "^[1-9][0-9]*$",
"title": "Variation Id"
},
"name": {
"type": "string",
"maxLength": 2000,
"minLength": 1,
"title": "Name"
},
"variant_type": {
"type": "string",
"maxLength": 200,
"minLength": 1,
"title": "Variant Type"
},
"germline": {
"anyOf": [
{
"type": "string",
"maxLength": 2000,
"minLength": 1
},
{
"type": "null"
}
],
"title": "Germline"
},
"germline_review_status": {
"anyOf": [
{
"type": "string",
"maxLength": 2000,
"minLength": 1
},
{
"type": "null"
}
],
"title": "Germline Review Status"
},
"somatic_clinical_impact": {
"anyOf": [
{
"type": "string",
"maxLength": 2000,
"minLength": 1
},
{
"type": "null"
}
],
"title": "Somatic Clinical Impact"
},
"somatic_review_status": {
"anyOf": [
{
"type": "string",
"maxLength": 2000,
"minLength": 1
},
{
"type": "null"
}
],
"title": "Somatic Review Status"
},
"oncogenicity": {
"anyOf": [
{
"type": "string",
"maxLength": 2000,
"minLength": 1
},
{
"type": "null"
}
],
"title": "Oncogenicity"
},
"oncogenicity_review_status": {
"anyOf": [
{
"type": "string",
"maxLength": 2000,
"minLength": 1
},
{
"type": "null"
}
],
"title": "Oncogenicity Review Status"
},
"source_url": {
"type": "string",
"maxLength": 2000,
"title": "Source Url"
},
"resolver_allele": {
"anyOf": [
{
"$ref": "#/$defs/ResolverAllele"
},
{
"type": "null"
}
]
},
"resolver_status": {
"type": "string",
"enum": [
"supported_exact_allele_requires_resolution",
"unsupported_or_no_unique_grch38_allele"
],
"title": "Resolver Status"
}
},
"additionalProperties": false,
"type": "object",
"required": [
"source_id",
"variation_id",
"name",
"variant_type",
"germline",
"germline_review_status",
"somatic_clinical_impact",
"somatic_review_status",
"oncogenicity",
"oncogenicity_review_status",
"source_url",
"resolver_allele",
"resolver_status"
],
"title": "ClinicalVariantExample"
},
"ClinicalVariantsData": {
"properties": {
"kind": {
"type": "string",
"const": "clinical_variants",
"title": "Kind"
},
"count_unit": {
"type": "string",
"const": "selected_variant_example",
"title": "Count Unit",
"default": "selected_variant_example"
},
"source_id": {
"type": "string",
"maxLength": 200,
"minLength": 1,
"title": "Source Id"
},
"unique_variation_total": {
"type": "integer",
"minimum": 0.0,
"title": "Unique Variation Total"
},
"membership_rule": {
"type": "string",
"const": "explicit_hgnc_or_unique_ncbi_gene_crosswalk",
"title": "Membership Rule"
},
"axes": {
"items": {
"$ref": "#/$defs/ClinicalAxis"
},
"type": "array",
"maxItems": 3,
"minItems": 3,
"title": "Axes"
},
"variant_type_counts": {
"items": {
"$ref": "#/$defs/DistributionBin"
},
"type": "array",
"maxItems": 1000,
"title": "Variant Type Counts"
},
"example_selection": {
"type": "string",
"const": "lowest_variation_id_bounded_50",
"title": "Example Selection"
},
"records": {
"items": {
"$ref": "#/$defs/ClinicalVariantExample"
},
"type": "array",
"maxItems": 50,
"title": "Records"
}
},
"additionalProperties": false,
"type": "object",
"required": [
"kind",
"source_id",
"unique_variation_total",
"membership_rule",
"axes",
"variant_type_counts",
"example_selection",
"records"
],
"title": "ClinicalVariantsData"
},
"CodingSegment": {
"properties": {
"rank": {
"type": "integer",
"minimum": 1.0,
"title": "Rank"
},
"start": {
"type": "integer",
"minimum": 1.0,
"title": "Start"
},
"end": {
"type": "integer",
"minimum": 1.0,
"title": "End"
},
"phase": {
"type": "integer",
"enum": [
0,
1,
2
],
"title": "Phase"
}
},
"additionalProperties": false,
"type": "object",
"required": [
"rank",
"start",
"end",
"phase"
],
"title": "CodingSegment"
},
"ConstraintData": {
"properties": {
"kind": {
"type": "string",
"const": "constraint",
"title": "Kind"
},
"count_unit": {
"type": "string",
"const": "source_metric_record",
"title": "Count Unit",
"default": "source_metric_record"
},
"records": {
"items": {
"$ref": "#/$defs/ConstraintMetric"
},
"type": "array",
"maxItems": 5000,
"title": "Records"
}
},
"additionalProperties": false,
"type": "object",
"required": [
"kind",
"records"
],
"title": "ConstraintData"
},
"ConstraintMetric": {
"properties": {
"source_gene_id": {
"anyOf": [
{
"type": "string",
"maxLength": 200,
"minLength": 1
},
{
"type": "null"
}
],
"title": "Source Gene Id"
},
"source_gene_namespace": {
"anyOf": [
{
"type": "string",
"enum": [
"ncbi_gene",
"ensembl_gene"
]
},
{
"type": "null"
}
],
"title": "Source Gene Namespace"
},
"source_canonical": {
"anyOf": [
{
"type": "boolean"
},
{
"type": "null"
}
],
"title": "Source Canonical"
},
"source_mane_select": {
"anyOf": [
{
"type": "boolean"
},
{
"type": "null"
}
],
"title": "Source Mane Select"
},
"source_id": {
"type": "string",
"maxLength": 200,
"minLength": 1,
"title": "Source Id"
},
"gene_id": {
"type": "string",
"pattern": "^HGNC:[1-9][0-9]*$",
"title": "Gene Id"
},
"transcript_id": {
"anyOf": [
{
"type": "string",
"maxLength": 200,
"minLength": 1
},
{
"type": "null"
}
],
"title": "Transcript Id"
},
"selection_rule": {
"type": "string",
"maxLength": 2000,
"minLength": 1,
"title": "Selection Rule"
},
"pli": {
"anyOf": [
{
"type": "number",
"maximum": 1.0,
"minimum": 0.0
},
{
"type": "null"
}
],
"title": "Pli"
},
"oe_lof": {
"anyOf": [
{
"type": "number",
"minimum": 0.0
},
{
"type": "null"
}
],
"title": "Oe Lof"
},
"oe_lof_lower": {
"anyOf": [
{
"type": "number",
"minimum": 0.0
},
{
"type": "null"
}
],
"title": "Oe Lof Lower"
},
"oe_lof_upper": {
"anyOf": [
{
"type": "number",
"minimum": 0.0
},
{
"type": "null"
}
],
"title": "Oe Lof Upper"
},
"observed_lof": {
"anyOf": [
{
"type": "integer",
"minimum": 0.0
},
{
"type": "null"
}
],
"title": "Observed Lof"
},
"oe_missense": {
"anyOf": [
{
"type": "number",
"minimum": 0.0
},
{
"type": "null"
}
],
"title": "Oe Missense"
},
"oe_missense_lower": {
"anyOf": [
{
"type": "number",
"minimum": 0.0
},
{
"type": "null"
}
],
"title": "Oe Missense Lower"
},
"oe_missense_upper": {
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"type": "number",
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{
"type": "null"
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],
"title": "Oe Missense Upper"
},
"observed_missense": {
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{
"type": "integer",
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},
{
"type": "null"
}
],
"title": "Observed Missense"
},
"expected_lof": {
"anyOf": [
{
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},
{
"type": "null"
}
],
"title": "Expected Lof"
},
"missense_z": {
"anyOf": [
{
"type": "number"
},
{
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}
],
"title": "Missense Z"
},
"quality_flags": {
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},
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},
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],
"title": "Expected Synonymous"
},
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{
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},
{
"type": "null"
}
],
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},
"display_status": {
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"caution",
"unreliable"
],
"title": "Display Status",
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},
"gene_flags": {
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},
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},
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"oe_lof_upper",
"observed_lof",
"expected_lof",
"missense_z",
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],
"title": "ConstraintMetric"
},
"DiseaseAssertion": {
"properties": {
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"maxLength": 200,
"minLength": 1,
"title": "Assertion Id"
},
"source_id": {
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"title": "Source Id"
},
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"title": "Disease Id"
},
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"title": "Disease Name"
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"inheritance": {
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],
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],
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],
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},
{
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],
"title": "Mirrored Assertion Id"
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},
{
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"submitter": {
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],
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},
{
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],
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"variant_consequence": {
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{
"type": "string",
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},
{
"type": "null"
}
],
"title": "Variant Consequence"
},
"pmids": {
"items": {
"type": "string",
"pattern": "^[1-9][0-9]*$"
},
"type": "array",
"maxItems": 500,
"title": "Pmids"
}
},
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"disease_id",
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"curation_date",
"panel",
"criteria_version",
"report_url"
],
"title": "DiseaseAssertion"
},
"DiseaseData": {
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"title": "Kind"
},
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"default": "source_assertion"
},
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},
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},
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"count"
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},
"DosageAssertion": {
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"minLength": 1,
"title": "Source Id"
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"1",
"2",
"3",
"30",
"40",
"Not yet evaluated",
"-1"
],
"title": "Score"
},
"description": {
"anyOf": [
{
"type": "string",
"maxLength": 2000,
"minLength": 1
},
{
"type": "null"
}
],
"title": "Description"
},
"disease_id": {
"anyOf": [
{
"type": "string",
"maxLength": 200,
"minLength": 1
},
{
"type": "null"
}
],
"title": "Disease Id"
},
"evaluated_at": {
"anyOf": [
{
"type": "string",
"maxLength": 200,
"minLength": 1
},
{
"type": "null"
}
],
"title": "Evaluated At"
},
"pmids": {
"items": {
"type": "string",
"pattern": "^[1-9][0-9]*$"
},
"type": "array",
"maxItems": 100,
"title": "Pmids"
},
"report_url": {
"type": "string",
"maxLength": 2000,
"title": "Report Url"
}
},
"additionalProperties": false,
"type": "object",
"required": [
"source_id",
"assertion_id",
"axis",
"score",
"description",
"disease_id",
"evaluated_at",
"pmids",
"report_url"
],
"title": "DosageAssertion"
},
"DosageData": {
"properties": {
"kind": {
"type": "string",
"const": "dosage",
"title": "Kind"
},
"count_unit": {
"type": "string",
"const": "source_dosage_assertion",
"title": "Count Unit",
"default": "source_dosage_assertion"
},
"records": {
"items": {
"$ref": "#/$defs/DosageAssertion"
},
"type": "array",
"maxItems": 5000,
"title": "Records"
}
},
"additionalProperties": false,
"type": "object",
"required": [
"kind",
"records"
],
"title": "DosageData"
},
"Exon": {
"properties": {
"rank": {
"type": "integer",
"minimum": 1.0,
"title": "Rank"
},
"start": {
"type": "integer",
"minimum": 1.0,
"title": "Start"
},
"end": {
"type": "integer",
"minimum": 1.0,
"title": "End"
}
},
"additionalProperties": false,
"type": "object",
"required": [
"rank",
"start",
"end"
],
"title": "Exon"
},
"ExpressionData": {
"properties": {
"kind": {
"type": "string",
"const": "expression",
"title": "Kind"
},
"count_unit": {
"type": "string",
"const": "provider_expression_category",
"title": "Count Unit",
"default": "provider_expression_category"
},
"records": {
"items": {
"$ref": "#/$defs/ExpressionRecord"
},
"type": "array",
"maxItems": 5000,
"title": "Records"
}
},
"additionalProperties": false,
"type": "object",
"required": [
"kind",
"records"
],
"title": "ExpressionData"
},
"ExpressionRecord": {
"properties": {
"source_id": {
"type": "string",
"maxLength": 200,
"minLength": 1,
"title": "Source Id"
},
"ensembl_gene_id": {
"type": "string",
"maxLength": 200,
"minLength": 1,
"title": "Ensembl Gene Id"
},
"tissue_id": {
"type": "string",
"maxLength": 200,
"minLength": 1,
"title": "Tissue Id"
},
"tissue_label": {
"type": "string",
"maxLength": 2000,
"minLength": 1,
"title": "Tissue Label"
},
"median_tpm": {
"anyOf": [
{
"type": "number",
"minimum": 0.0
},
{
"type": "null"
}
],
"title": "Median Tpm"
},
"unit": {
"type": "string",
"const": "TPM",
"title": "Unit"
},
"statistic": {
"type": "string",
"const": "median",
"title": "Statistic"
},
"s
# --- truncated at 32 KB (57 KB total) ---
# Full source: https://artifacts.apis.io/helena-bio/json-schema/helena-bio-section-response-schema.json
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