amicus-therapeutics · Schema

Amicus Medicine

A marketed Amicus Therapeutics medicine, including its trade name, generic name, indication, mechanism, and approval status.

BiotechnologyPharmaceuticalsRare DiseasesGenetic DiseasesFabry DiseasePompe DiseaseLysosomal Storage DisordersEnzyme Replacement TherapyPharmacological ChaperonesClinical ResearchLife SciencesPatient Advocacy

Properties

Name	Type	Description
medicineId	string	Stable identifier for the Amicus medicine record
brandName	string	Registered brand / trade name (e.g., Galafold, Pombiliti, Opfolda)
genericName	string	International nonproprietary name (e.g., migalastat)
drugClass	string	Therapeutic class of the medicine
routeOfAdministration	string	How the medicine is administered to patients
indication	string	Approved disease indication (e.g., Fabry disease, late-onset Pompe disease)
patientPopulation	string	Eligible patient population description (e.g., adults with amenable GLA variant)
combinationWith	array	Other medicines required as part of the regimen (e.g., Opfolda combined with Pombiliti)
mechanismOfAction	string	Brief description of how the medicine works
approvals	array
productSite	string	Public product / patient information website

View JSON Schema on GitHub

JSON Schema

{
  "$schema": "https://json-schema.org/draft/2020-12/schema",
  "$id": "https://api-evangelist.github.io/amicus-therapeutics/json-schema/amicus-medicine-schema.json",
  "title": "Amicus Medicine",
  "description": "A marketed Amicus Therapeutics medicine, including its trade name, generic name, indication, mechanism, and approval status.",
  "type": "object",
  "required": ["medicineId", "brandName", "genericName", "indication"],
  "properties": {
    "medicineId": {
      "type": "string",
      "description": "Stable identifier for the Amicus medicine record"
    },
    "brandName": {
      "type": "string",
      "description": "Registered brand / trade name (e.g., Galafold, Pombiliti, Opfolda)"
    },
    "genericName": {
      "type": "string",
      "description": "International nonproprietary name (e.g., migalastat)"
    },
    "drugClass": {
      "type": "string",
      "enum": [
        "Pharmacological Chaperone",
        "Enzyme Replacement Therapy",
        "Enzyme Stabilizer",
        "Small Molecule",
        "Biologic"
      ],
      "description": "Therapeutic class of the medicine"
    },
    "routeOfAdministration": {
      "type": "string",
      "enum": ["Oral", "Intravenous", "Subcutaneous", "Intramuscular", "Inhaled"],
      "description": "How the medicine is administered to patients"
    },
    "indication": {
      "type": "string",
      "description": "Approved disease indication (e.g., Fabry disease, late-onset Pompe disease)"
    },
    "patientPopulation": {
      "type": "string",
      "description": "Eligible patient population description (e.g., adults with amenable GLA variant)"
    },
    "combinationWith": {
      "type": "array",
      "items": { "type": "string" },
      "description": "Other medicines required as part of the regimen (e.g., Opfolda combined with Pombiliti)"
    },
    "mechanismOfAction": {
      "type": "string",
      "description": "Brief description of how the medicine works"
    },
    "approvals": {
      "type": "array",
      "items": {
        "type": "object",
        "required": ["region", "agency"],
        "properties": {
          "region": {
            "type": "string",
            "description": "Geographic / regulatory region (e.g., EU, US, Japan)"
          },
          "agency": {
            "type": "string",
            "description": "Approving authority (e.g., FDA, EC, EMA, PMDA)"
          },
          "approvalDate": {
            "type": "string",
            "format": "date",
            "description": "Date of approval"
          }
        }
      }
    },
    "productSite": {
      "type": "string",
      "format": "uri",
      "description": "Public product / patient information website"
    }
  },
  "additionalProperties": false
}