UniProt · Rate Limits

Default

UniProt REST API (rest.uniprot.org) does not publicly document a hard rate limit but asks users to be considerate and use pagination or streaming for large result sets. The EBI Proteins API (www.ebi.ac.uk/proteins/api) enforces a limit of 200 requests per second per user. The SPARQL endpoint imposes a 45-minute query timeout. No authentication is required for any endpoint.

Default is the machine-readable rate-limit profile for UniProt on the APIs.io network, in the API Commons Rate Limits shape.

It captures 3 rate-limit definitions.

This profile was written by API Evangelist and has not been verified against a page the provider published; treat every limit as unconfirmed until a dated transcription replaces it.

Tagged areas include Proteins, Bioinformatics, Genomics, Life Sciences, and Open Data.

3 Limits
Method: generated.
Written by API Evangelist and not verified against a page the provider published. Treat every limit as unconfirmed until a dated transcription replaces it.
View Source
ProteinsBioinformaticsGenomicsLife SciencesOpen Data

Limits

per user
https://www.ebi.ac.uk/proteins/api
https://sparql.uniprot.org/sparql
https://rest.uniprot.org
No hard limit published. Recommended to use streaming (size=-1) or pagination for large downloads. Cursor-based pagination via Link header for sequential page traversal.

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Tools for rate limits

4 MCP tools reach this
  • find_rate_limitsBrowse and filter every rate limit in the catalog.
  • apis_io_searchSTART HERE — APIs, providers and tags for one query, each with its total.
  • resolveTurn a domain, URL or GitHub org into the provider it belongs to.
  • find_cohortsEvery scored population of providers in the catalog.
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Call it yourself

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This rate limit 
curl "https://apis.io/api/v1/rate-limits/default"
All rate limits 
curl "https://apis.io/api/v1/rate-limits?limit=25"

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