UniProt · Rate Limits

Default

UniProt REST API (rest.uniprot.org) does not publicly document a hard rate limit but asks users to be considerate and use pagination or streaming for large result sets. The EBI Proteins API (www.ebi.ac.uk/proteins/api) enforces a limit of 200 requests per second per user. The SPARQL endpoint imposes a 45-minute query timeout. No authentication is required for any endpoint.

Default is the machine-readable rate-limit profile for UniProt on the APIs.io network, conforming to the API Commons Rate Limits specification.

It captures 3 rate-limit definitions.

Tagged areas include Proteins, Bioinformatics, Genomics, Life Sciences, and Open Data.

3 Limits
ProteinsBioinformaticsGenomicsLife SciencesOpen Data

Limits

per user
No hard limit published. Recommended to use streaming (size=-1) or pagination for large downloads. Cursor-based pagination via Link header for sequential page traversal.

Work with this as data

Every rate limit here is available over the APIs.io API and to AI agents over MCP.

MCP server

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https://apis.io/mcp

Tools for rate limits

4 MCP tools reach this
  • find_rate_limitsBrowse and filter every rate limit in the catalog.
  • apis_io_searchSTART HERE — APIs, providers and tags for one query, each with its total.
  • resolveTurn a domain, URL or GitHub org into the provider it belongs to.
  • find_cohortsEvery scored population of providers in the catalog.
All 92 tools

Call it yourself

curl for this page
This rate limit 
curl "https://apis.io/api/v1/rate-limits/default"
All rate limits 
curl "https://apis.io/api/v1/rate-limits?limit=25"

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