WritersLogic Verifiable AI Agent Hub Mine Abandoned Compounds API
The Mine Abandoned Compounds API from WritersLogic Verifiable AI Agent Hub — 1 operation(s) for mine abandoned compounds.
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curl "https://apis.io/api/v1/apis/writerslogic-com:writerslogic-com-mine-abandoned-compounds-api"
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OpenAPI Specification
openapi: 3.2.0
info:
title: WritersLogic Verifiable AI Agent Hub Mine Abandoned…
version: 2.0.0
description: Pay-per-call agents settled in USDC on Base via x402. Every response carries a signed provenance envelope.
contact:
name: WritersLogic
url: https://writerslogic.com/agents
email: agents@writerslogic.com
servers:
- url: https://agents.writerslogic.com
tags:
- name: Mine Abandoned Compounds
paths:
/api/v1/mine-abandoned-compounds:
post:
operationId: abandoned_compound_miner
summary: Abandoned Compound & Uncommercialized Trial Miner
description: 'Finds shelved drug and biologic candidates worth a second look. Give a disease or target (mines ClinicalTrials.gov for terminated, withdrawn and suspended trials and for completed Phase 1/2 non-industry trials with no later industry Phase 2/3/4 trial), a compound you already have in mind (drug name or ChEMBL id), a trial (NCT id), or a desired material property (literature mode, no trials). Every candidate is screened in code: the stop reason is classified by keyword rules (one fast model call only for an ambiguous reason or a missing mechanism, accepted only with a verbatim quote), ChEMBL and the FDA Orange Book exclude approved, withdrawn and boxed-warning molecules, and any safety, toxicity or drug-versus-placebo adverse-event excess excludes the candidate. The response leads with a verdict (PROMISING, WORTH_INVESTIGATING, WEAK, INSUFFICIENT_EVIDENCE or NO_CANDIDATES), a confidence level, the top pick and a concrete next step, then a Repurposing Dossier per survivor: trials with NCT links, mechanism, shelving reason, safety and dosage facts with quotes, estimated IP window, US regulatory pathway with non-compliant routes flagged, evidence grade, computed concerns and a deterministic de-risk score. If an index or the model is unavailable you still get a signed partial result that names what is missing. The screens can only exclude, never clear a compound, and a registry search misses unregistered and non-US programs. Not medical, legal, patent or regulatory advice.
Price: 2.00 USDC on Base (x402).'
x-x402-price-usdc: '2.00'
x-x402-amount: '2000000'
x-payment-info:
protocols:
- x402
price:
mode: fixed
currency: USD
amount: '2.00'
x-audience: research
x-sample-url: https://agents.writerslogic.com/api/v1/samples/abandoned-compound-miner
security:
- x402: []
- apiKey: []
requestBody:
required: true
content:
application/json:
schema:
type: object
additionalProperties: false
properties:
biologicalTargetOrCondition:
type: string
minLength: 2
maxLength: 200
description: Disease, condition or biological target (e.g. "amyotrophic lateral sclerosis", "BACE1"). Mines stopped and completed-without-follow-up clinical trials.
materialProperty:
type: string
minLength: 2
maxLength: 200
description: Desired material property (e.g. "high ionic conductivity solid electrolyte"). Mines the literature indexes; no trials are involved.
compound:
type: string
minLength: 2
maxLength: 200
description: A compound you already have in mind, as a drug name or ChEMBL id (e.g. "edaravone", "CHEMBL290916"). Returns whether it is an abandoned, safe-to-pursue candidate or why it was excluded (marketed, safety signal, active development). Replaces the condition search.
nctId:
type: string
pattern: ^(?:NCT|nct)\d{8}$
description: A ClinicalTrials.gov trial id (e.g. "NCT01257048"). The compound it tested is reviewed as with `compound`.
includeCompletedNoFollowUp:
type: boolean
description: Include completed Phase 1/2 non-industry trials with no later industry Phase 2/3/4 trial of the same intervention. Default true.
maxCandidates:
type: integer
minimum: 1
maximum: 8
description: Dossiers to produce (default 4, max 8). Model cost is at most one fast call per candidate.
example:
biologicalTargetOrCondition: amyotrophic lateral sclerosis
includeCompletedNoFollowUp: true
maxCandidates: 4
responses:
'200':
description: Paid result with provenance
content:
application/json:
schema:
type: object
properties:
data:
type: object
properties:
verdict:
type: string
enum:
- PROMISING
- WORTH_INVESTIGATING
- WEAK
- INSUFFICIENT_EVIDENCE
- NO_CANDIDATES
description: Best dossier's verdict (PROMISING, WORTH_INVESTIGATING, WEAK, INSUFFICIENT_EVIDENCE) or NO_CANDIDATES.
confidence_level:
anyOf:
- type: string
enum:
- HIGH
- MEDIUM
- LOW
- type: 'null'
description: 'HIGH: evidence grade A/B, complete safety screen, no warnings. MEDIUM: grade A-C with a complete screen. LOW otherwise. Null with no dossier.'
top_pick:
anyOf:
- type: object
description: compound, verdict, de_risk_score, evidence_grade, shelving_category, nct_id, url, patent_status.
- type: 'null'
summary:
type: string
description: Plain-language result in two sentences.
next_step:
type: string
description: Concrete recommended action.
partial:
type: boolean
description: True when a source, model review or candidate was unavailable; see missing.
missing:
type: array
items:
type: string
query:
type: object
result:
type: string
enum:
- CANDIDATES_FOUND
- NO_CANDIDATES
dossiers:
type: array
items:
type: object
excluded:
type: array
items:
type: object
description: Compounds removed by deterministic rules, with signals and quotes.
funnel:
type: object
what_would_change_the_call:
type: array
items:
type: string
limitations:
type: array
items:
type: string
warnings:
type: array
items:
type: string
candidate_errors:
type: array
items:
type: object
description: Candidates whose review failed; the remaining candidates are still returned.
disclaimer:
type: string
analyzed_at:
type: string
_provenance:
type: object
description: C2PA-aligned manifest and W3C VC 2.0 (eddsa-jcs-2022) issued by the hub DID; verify at POST /api/v1/verify-provenance
required:
- data
- _provenance
'400':
description: Invalid request (no payment consumed)
content:
application/json:
schema:
type: object
properties:
error:
type: string
code:
type: string
'401':
description: Invalid X-API-KEY
content:
application/json:
schema:
type: object
properties:
error:
type: string
code:
type: string
'402':
description: Payment required or invalid
content:
application/json:
schema:
type: object
description: x402 v2 PaymentRequired (also base64 in the PAYMENT-REQUIRED header)
properties:
x402Version:
type: integer
error:
type: string
code:
type: string
resource:
type: object
accepts:
type: array
items:
type: object
extensions:
type: object
'502':
description: Upstream failure; the payment is released or not settled
content:
application/json:
schema:
type: object
properties:
error:
type: string
code:
type: string
tags:
- Mine Abandoned Compounds
components:
securitySchemes:
x402:
type: apiKey
in: header
name: PAYMENT-SIGNATURE
description: x402 v2 payment payload (base64) sent after a 402 challenge
apiKey:
type: apiKey
in: header
name: X-API-KEY