Thermo Fisher Scientific Measurements API

openapi: 3.1.0
info:
  title: Thermo Fisher NanoDrop Ultra Web Authentication Measurements API
  description: The Thermo Scientific NanoDrop Ultra Web API provides RESTful access to instrument control and data retrieval for the NanoDrop Ultra microvolume UV-Vis spectrophotometer and fluorometer. Enables laboratory informatics integration, automated measurement workflows, sample data export, and instrument status monitoring.
  version: 1.0.0
  contact:
    name: Thermo Fisher Scientific
    url: https://www.thermofisher.com/us/en/home/industrial/spectroscopy-elemental-isotope-analysis/molecular-spectroscopy/uv-vis-spectrophotometry/instruments/nanodrop.html
  license:
    name: Proprietary
    url: https://www.thermofisher.com
servers:
- url: http://{instrument-ip}:{port}
  description: NanoDrop Ultra instrument local network API
  variables:
    instrument-ip:
      description: IP address of the NanoDrop Ultra instrument on the local network.
      default: 192.168.1.100
    port:
      description: API port.
      default: '8080'
tags:
- name: Measurements
  description: Sample measurements and spectra.
paths:
  /api/measure:
    post:
      operationId: performMeasurement
      summary: Perform Measurement
      description: Initiates a sample measurement on the NanoDrop Ultra instrument using the specified method. The instrument must have a sample loaded on the pedestal before calling this endpoint.
      tags:
      - Measurements
      requestBody:
        required: true
        content:
          application/json:
            schema:
              $ref: '#/components/schemas/MeasurementRequest'
      responses:
        '200':
          description: Measurement completed successfully.
          content:
            application/json:
              schema:
                $ref: '#/components/schemas/MeasurementResult'
        '400':
          description: Invalid measurement request.
        '503':
          description: Instrument busy or not ready.
  /api/measurements:
    get:
      operationId: getMeasurements
      summary: Get Measurements
      description: Retrieves a list of stored measurements from the NanoDrop Ultra database. Supports filtering by date, sample ID, and method.
      tags:
      - Measurements
      parameters:
      - name: from_date
        in: query
        required: false
        schema:
          type: string
          format: date
        description: Filter measurements from this date.
      - name: to_date
        in: query
        required: false
        schema:
          type: string
          format: date
        description: Filter measurements to this date.
      - name: method
        in: query
        required: false
        schema:
          type: string
        description: Filter by measurement method name.
      - name: sample_id
        in: query
        required: false
        schema:
          type: string
        description: Filter by sample identifier.
      - name: limit
        in: query
        required: false
        schema:
          type: integer
          default: 100
        description: Maximum number of records to return.
      - name: offset
        in: query
        required: false
        schema:
          type: integer
          default: 0
        description: Pagination offset.
      responses:
        '200':
          description: Measurement list returned successfully.
          content:
            application/json:
              schema:
                $ref: '#/components/schemas/MeasurementListResponse'
  /api/measurements/{measurementId}:
    get:
      operationId: getMeasurementById
      summary: Get Measurement By ID
      description: Returns the full measurement data including spectrum for a specific measurement.
      tags:
      - Measurements
      parameters:
      - name: measurementId
        in: path
        required: true
        schema:
          type: string
        description: The unique measurement identifier.
      responses:
        '200':
          description: Measurement data returned successfully.
          content:
            application/json:
              schema:
                $ref: '#/components/schemas/MeasurementResult'
        '404':
          description: Measurement not found.
components:
  schemas:
    MeasurementResult:
      type: object
      properties:
        measurement_id:
          type: string
          description: Unique measurement identifier.
        sample_id:
          type: string
          description: Sample identifier.
        sample_name:
          type: string
          description: Sample display name.
        method:
          type: string
          description: Measurement method used.
        timestamp:
          type: string
          format: date-time
          description: Measurement timestamp.
        operator:
          type: string
          description: Operator who performed the measurement.
        concentration:
          type: number
          description: Calculated concentration (ng/µL or µg/mL depending on method).
        unit:
          type: string
          description: Concentration unit.
        a260:
          type: number
          description: Absorbance at 260 nm.
        a280:
          type: number
          description: Absorbance at 280 nm.
        a260_a280_ratio:
          type: number
          description: A260/A280 purity ratio.
        a260_a230_ratio:
          type: number
          description: A260/A230 purity ratio.
        spectrum:
          type: array
          description: Full UV-Vis absorbance spectrum data points.
          items:
            type: object
            properties:
              wavelength:
                type: number
                description: Wavelength in nm.
              absorbance:
                type: number
                description: Absorbance value.
    MeasurementRequest:
      type: object
      required:
      - method
      properties:
        method:
          type: string
          description: Name of the measurement method to use.
        sample_id:
          type: string
          description: Sample identifier to associate with the measurement.
        sample_name:
          type: string
          description: Sample display name.
        operator:
          type: string
          description: Operator name.
        notes:
          type: string
          description: Optional measurement notes.
    MeasurementListResponse:
      type: object
      properties:
        total:
          type: integer
        measurements:
          type: array
          items:
            $ref: '#/components/schemas/MeasurementResult'