Onepot

Onepot API

Programmatic access to onepot CORE for make-on-demand molecule discovery and synthesis. Run similarity (Tanimoto) and substructure (SMILES/SMARTS) search, optional retrosynthetic decomposition with building-block/price/risk filters, stream progress and results over server-sent events, and place synthesis orders. Accessed via the first-party Python client (pip install onepot) using an API key; access is gated ("Request API access").

GitHub

Documentation

📖
Documentation
https://www.onepot.ai/api
📖
GettingStarted
https://www.onepot.ai/api

Other Resources

🔗
APIsJSON
https://raw.githubusercontent.com/api-evangelist/onepot/refs/heads/main/apis.yml

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API entry from apis.yml

apis.yml Raw ↑ 
name: Onepot API
description: Programmatic access to onepot CORE for make-on-demand molecule discovery and synthesis. Run
  similarity (Tanimoto) and substructure (SMILES/SMARTS) search, optional retrosynthetic decomposition
  with building-block/price/risk filters, stream progress and results over server-sent events, and place
  synthesis orders. Accessed via the first-party Python client (pip install onepot) using an API key;
  access is gated ("Request API access").
humanURL: https://www.onepot.ai/api
baseURL: https://www.onepot.ai
tags:
- Chemistry
- Cheminformatics
- Molecule Search
- Retrosynthesis
- Synthesis
properties:
- type: Documentation
  url: https://www.onepot.ai/api
- type: GettingStarted
  url: https://www.onepot.ai/api