National Center for Biotechnology Information (NCBI)

National Center for Biotechnology Information (NCBI) Gene API

#### Options to download gene data, including the associated sequence and metadata. These gene services allow you to get gene metadata as a data report or download gene, transcript and protein sequence, and metadata, as a gene data package, for all genes in NCBI Gene.

GitHub OpenAPI

Operations 28

GET /gene/id/{gene_ids}/download Get a gene data package by GeneID #
POST /gene/download Get a gene data package #
GET /gene/id/{gene_ids} Get gene reports by GeneID #
GET /gene/accession/{accessions} Get gene metadata by RefSeq Accession #
GET /gene/symbol/{symbols}/taxon/{taxon} Get gene metadata by gene symbol #
GET /gene/taxon/{taxon} Get gene reports by taxonomic identifier #
POST /gene Get gene metadata as JSON #
GET /gene/id/{gene_ids}/dataset_report Get a gene data report by GeneID #
GET /gene/accession/{accessions}/dataset_report Get a gene data report by RefSeq nucleotide or protein accession #
GET /gene/symbol/{symbols}/taxon/{taxon}/dataset_report Get a gene data report by symbol and taxon #
GET /gene/taxon/{taxon}/dataset_report Get a gene data report by taxon #
GET /gene/locus_tag/{locus_tags}/dataset_report Get a gene data report by locus tag #
POST /gene/dataset_report Get a gene data report #
GET /gene/id/{gene_ids}/product_report Get a gene product report by GeneID #
GET /gene/accession/{accessions}/product_report Get a gene product report by RefSeq nucleotide or protein accession #
GET /gene/symbol/{symbols}/taxon/{taxon}/product_report Get a gene product report by symbol and taxon #
GET /gene/taxon/{taxon}/product_report Get a gene product report by taxon #
GET /gene/locus_tag/{locus_tags}/product_report Get a gene product report by locus tag #
POST /gene/product_report Get a gene product report #
GET /gene/id/{gene_ids}/download_summary Get a download summary of a gene data package by GeneID #
POST /gene/download_summary Get a download summary of a gene data package #
GET /gene/taxon/{taxon}/counts Get gene counts by taxon #
POST /gene/taxon/counts Get gene counts by taxon #
GET /gene/id/{gene_id}/orthologs Get a gene data report for a gene ortholog set by GeneID #
POST /gene/orthologs Get a gene data report for a gene ortholog set by GeneID #
POST /gene/links Get gene links by GeneID #
GET /gene/taxon/{taxon}/annotation/{annotation_name}/chromosome_summary Get gene counts per chromosome by taxon and annotation name #

Documentation

📖
Documentation
https://www.ncbi.nlm.nih.gov/datasets/docs/v2/api/rest-api/
📖
RateLimits
https://kinlane.github.io/ncbi/rate-limits/datasets.yml

Specifications

⚙
OpenAPI
https://raw.githubusercontent.com/api-evangelist/ncbi/refs/heads/main/openapi/ncbi-gene-api-openapi.yml

Other Resources

🔗
Plans
https://kinlane.github.io/ncbi/plans/datasets.yml

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OpenAPI Specification

ncbi-gene-api-openapi.yml Raw ↑ 
openapi: 3.2.0
info:
  title: NCBI Datasets Gene API
  version: v2
  description: '### NCBI Datasets is a resource that lets you easily gather data from NCBI.

    The NCBI Datasets version 2 API is updated often to add new features, fix bugs, and enhance usability.'
servers:
- url: https://api.ncbi.nlm.nih.gov/datasets/v2
security:
- ApiKeyAuthHeader: []
tags:


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# Full source: https://raw.githubusercontent.com/api-evangelist/ncbi/refs/heads/main/openapi/ncbi-gene-api-openapi.yml