ExchangeRebel NADAC Facts API
The NADAC Facts API from ExchangeRebel — 6 operation(s) for nadac facts.
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curl "https://apis.io/api/v1/apis/exchangerebel-com:exchangerebel-com-nadac-facts-api"
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OpenAPI Specification
openapi: 3.2.0
info:
title: ExchangeRebel — pay-per-call APIs for AI agents (x402 on…
version: 1.0.0
contact:
name: 'ExchangeRebel (operator: Rebel Data)'
url: https://exchangerebel.com
email: sound.money.investing@gmail.com
x-guidance: 'All paid operations use x402 on Solana: call without payment to get a 402 challenge (SOL recipient + USDC token account + fresh memo), pay with the memo attached via the Solana Memo program, then retry with header X-Payment-Tx: <signature> and ?toll_memo=<memo>. Challenges are dual-version: the PAYMENT-REQUIRED header carries the x402 v2 PaymentRequired object and the response body carries the same challenge in x402 v1 form for compatibility. Free operations (security: []) include each service''s /health catalog with full response shapes. Prices in x-payment-info are USD per call unless the summary says otherwise (RPC is per 1,000-request block; Telegram provisioning is per bot-month; transcription is per minute of audio).'
description: '67 data and utility APIs behind x402 tolls, settled in SOL or USDC on Solana. Call a paid endpoint without payment to receive a 402 x402 challenge (recipient + fresh memo), pay with the memo attached via the Solana Memo program, then retry with the X-Payment-Tx header and toll_memo query parameter. Free catalog/health endpoints are marked without x-payment-info. Full catalogs: GET /toll/discovery and each service''s /health.'
servers:
- url: https://exchangerebel.com
tags:
- name: NADAC Facts
paths:
/toll/nadac:
get:
tags:
- NADAC Facts
summary: 'NADAC facts catalog: labels only (free)'
responses:
'200':
description: Success. Response shape is documented in the service catalog (GET /health on the service).
security: []
operationId: getTollNadac
x-operation-id-source: derived
/toll/nadac/catalog:
get:
tags:
- NADAC Facts
summary: NADAC facts catalog (labels only). Free
responses:
'200':
description: Success. Response shape is documented in the service catalog (GET /health on the service).
security: []
operationId: getTollNadacCatalog
x-operation-id-source: derived
post:
tags:
- NADAC Facts
summary: NADAC facts catalog (labels only). Free
responses:
'200':
description: Success. Response shape is documented in the service catalog (GET /health on the service).
security: []
operationId: postTollNadacCatalog
x-operation-id-source: derived
/toll/nadac/changes:
post:
tags:
- NADAC Facts
summary: Fetch per-NDC NADAC values across generations
responses:
'200':
description: Success. Response shape is documented in the service catalog (GET /health on the service).
content:
application/json:
example:
results:
- ndc: '11111111111'
ndc_description: FIXTURE ALPHA 10 MG TABLET
generations:
- as_of_date: '2025-10-15'
nadac_per_unit: 1
- as_of_date: '2026-09-16'
nadac_per_unit: 2
- as_of_date: '2026-10-07'
nadac_per_unit: 2
- as_of_date: '2026-10-14'
nadac_per_unit: 2.5
latest_vs_previous:
from_as_of: '2026-10-07'
from_per_unit: 2
to_as_of: '2026-10-14'
to_per_unit: 2.5
delta_abs: 0.5
delta_pct: 25
latest_vs_12m_anchor:
from_as_of: '2025-10-15'
from_per_unit: 1
to_as_of: '2026-10-14'
to_per_unit: 2.5
delta_abs: 1.5
delta_pct: 150
as_of: '2026-10-14'
label: National average pharmacy acquisition cost (NADAC), as of 2026-10-14 — a pharmacy acquisition benchmark published by CMS; not a consumer, cash, or coupon price.
- ndc: '77777777777'
ndc_description: FIXTURE OLD 2 MG TABLET
generations:
- as_of_date: '2025-10-15'
nadac_per_unit: 0.5
- as_of_date: '2026-09-16'
nadac_per_unit: null
- as_of_date: '2026-10-07'
nadac_per_unit: null
- as_of_date: '2026-10-14'
nadac_per_unit: null
latest_vs_previous:
from_as_of: '2026-10-07'
from_per_unit: null
to_as_of: '2026-10-14'
to_per_unit: null
delta_abs: null
delta_pct: null
latest_vs_12m_anchor:
from_as_of: '2025-10-15'
from_per_unit: 0.5
to_as_of: '2026-10-14'
to_per_unit: null
delta_abs: null
delta_pct: null
as_of: '2026-10-14'
label: National average pharmacy acquisition cost (NADAC), as of 2026-10-14 — a pharmacy acquisition benchmark published by CMS; not a consumer, cash, or coupon price.
- ndc: '99999999999'
covered: false
generations: []
latest_vs_previous: null
latest_vs_12m_anchor: null
generations_held:
- '2025-10-15'
- '2026-09-16'
- '2026-10-07'
- '2026-10-14'
as_of: '2026-10-14'
label: National average pharmacy acquisition cost (NADAC), as of 2026-10-14 — a pharmacy acquisition benchmark published by CMS; not a consumer, cash, or coupon price.
toll:
usdc_units: 10000
sol_lamports: 68000
toll_usd: 0.01
'402':
description: 'Payment Required (x402). The PAYMENT-REQUIRED response header carries the x402 v2 PaymentRequired object (base64 JSON: scheme, CAIP-2 network, amount, asset, payTo, plus the bazaar discovery extension); the response body carries the same challenge in x402 v1 form for compatibility, naming the SOL recipient and USDC token account on Solana plus a fresh memo. To pay on this service''s rail: pay with the memo attached (Solana Memo program), then retry with header ''X-Payment-Tx: <transaction signature>'' and query parameter ''toll_memo=<memo>''.'
requestBody:
content:
application/json:
schema:
type: object
properties:
ndc:
type: string
description: string
ndcs:
type: array
description: array
items:
type: string
x-payment-info:
protocols:
- x402
price:
mode: fixed
currency: USD
amount: '0.01'
security:
- x402Payment: []
operationId: postTollNadacChanges
x-operation-id-source: derived
/toll/nadac/dispersion:
post:
tags:
- NADAC Facts
summary: Fetch NADAC dispersion across presentations
responses:
'200':
description: Success. Response shape is documented in the service catalog (GET /health on the service).
content:
application/json:
example:
ndc: '44444444444'
ndc_description: FIXTURE GAMMA 5 MG TABLET
as_of_date: '2026-10-14'
presentations:
- ndc: '33333333333'
nadac_per_unit: 1
pricing_unit: EA
classification_for_rate_setting: G
- ndc: '44444444444'
nadac_per_unit: 3
pricing_unit: EA
classification_for_rate_setting: G
- ndc: '55555555555'
nadac_per_unit: 5
pricing_unit: EA
classification_for_rate_setting: B
- ndc: '66666666666'
nadac_per_unit: 7
pricing_unit: EA
classification_for_rate_setting: B-ANDA
stats:
count: 4
min: 1
max: 7
median: 4
mean: 4
brand_generic:
brand_count: 2
generic_count: 2
brand_median: 6
generic_median: 2
gap_abs: 4
gap_pct: 200
as_of: '2026-10-14'
label: National average pharmacy acquisition cost (NADAC), as of 2026-10-14 — a pharmacy acquisition benchmark published by CMS; not a consumer, cash, or coupon price.
toll:
usdc_units: 20000
sol_lamports: 136000
toll_usd: 0.02
'402':
description: 'Payment Required (x402). The PAYMENT-REQUIRED response header carries the x402 v2 PaymentRequired object (base64 JSON: scheme, CAIP-2 network, amount, asset, payTo, plus the bazaar discovery extension); the response body carries the same challenge in x402 v1 form for compatibility, naming the SOL recipient and USDC token account on Solana plus a fresh memo. To pay on this service''s rail: pay with the memo attached (Solana Memo program), then retry with header ''X-Payment-Tx: <transaction signature>'' and query parameter ''toll_memo=<memo>''.'
requestBody:
content:
application/json:
schema:
type: object
properties:
ndc:
type: string
description: string (required)
required:
- ndc
x-payment-info:
protocols:
- x402
price:
mode: fixed
currency: USD
amount: '0.02'
security:
- x402Payment: []
operationId: postTollNadacDispersion
x-operation-id-source: derived
/toll/nadac/fact:
post:
tags:
- NADAC Facts
summary: Fetch one per-NDC NADAC fact. $0.01
responses:
'200':
description: Success. Response shape is documented in the service catalog (GET /health on the service).
content:
application/json:
example:
ndc: '11111111111'
ndc_description: FIXTURE ALPHA 10 MG TABLET
nadac_per_unit: 2.5
pricing_unit: EA
effective_date: '2026-10-01'
as_of_date: '2026-10-14'
classification_for_rate_setting: G
pharmacy_type_indicator: C/I
otc: N
explanation_code: '1'
corresponding_generic_drug_nadac_per_unit: null
corresponding_generic_drug_effective_date: null
generic_gap_abs: null
generic_gap_pct: null
changes:
- horizon: ~1 week
from_as_of: '2026-10-07'
from_per_unit: 2
delta_abs: 0.5
delta_pct: 25
- horizon: ~1 month
from_as_of: '2026-09-16'
from_per_unit: 2
delta_abs: 0.5
delta_pct: 25
- horizon: ~6 months
from_as_of: null
from_per_unit: null
delta_abs: null
delta_pct: null
- horizon: 12 months
from_as_of: '2025-10-15'
from_per_unit: 1
delta_abs: 1.5
delta_pct: 150
as_of: '2026-10-14'
label: National average pharmacy acquisition cost (NADAC), as of 2026-10-14 — a pharmacy acquisition benchmark published by CMS; not a consumer, cash, or coupon price.
toll:
usdc_units: 10000
sol_lamports: 68000
toll_usd: 0.01
'402':
description: 'Payment Required (x402). The PAYMENT-REQUIRED response header carries the x402 v2 PaymentRequired object (base64 JSON: scheme, CAIP-2 network, amount, asset, payTo, plus the bazaar discovery extension); the response body carries the same challenge in x402 v1 form for compatibility, naming the SOL recipient and USDC token account on Solana plus a fresh memo. To pay on this service''s rail: pay with the memo attached (Solana Memo program), then retry with header ''X-Payment-Tx: <transaction signature>'' and query parameter ''toll_memo=<memo>''.'
requestBody:
content:
application/json:
schema:
type: object
properties:
ndc:
type: string
description: string (required)
required:
- ndc
x-payment-info:
protocols:
- x402
price:
mode: fixed
currency: USD
amount: '0.01'
security:
- x402Payment: []
operationId: postTollNadacFact
x-operation-id-source: derived
/toll/nadac/health:
get:
tags:
- NADAC Facts
summary: NADAC facts health (free)
responses:
'200':
description: Success. Response shape is documented in the service catalog (GET /health on the service).
security: []
operationId: getTollNadacHealth
x-operation-id-source: derived
components:
securitySchemes:
x402Payment:
type: apiKey
in: header
name: X-Payment-Tx
description: 'x402 toll payment proof: the Solana transaction signature of a payment carrying the memo from the 402 challenge; send together with ?toll_memo=<memo>. Payment itself is made on-chain in SOL or USDC to the recipient named in the challenge.'