Benchling Oligo Duplex API

An oligo duplex is a therapeutic modality consisting of two complementary oligonucleotide strands (forward and reverse) with optional conjugate molecules attached to either strand. The classic example is siRNA (small interfering RNA), which uses double-stranded RNA for gene silencing. The forwardStrand and reverseStrand reference the underlying oligo entities, with hydrogen bonds automatically computed for base pairing. Structure is defined using HELM notation and can be edited via the visual structure editor. Supports versioning (see OligoDuplexVersion) to track changes over time.

Operations 9

POST /oligo-duplex Create OligoDuplex #
GET /oligo-duplex/items List OligoDuplex items #
GET /oligo-duplex/{oligo_duplex_id} Get OligoDuplex by ID #
PATCH /oligo-duplex/{oligo_duplex_id} Update OligoDuplex #
GET /oligo-duplex/{oligo_duplex_id}/authors/items List Principal items #
POST /oligo-duplex:batch-create Batch create OligoDuplex #
PATCH /oligo-duplex:batch-update Batch update OligoDuplex #
POST /oligo-duplex:bulk-create Bulk create OligoDuplex #
PATCH /oligo-duplex:bulk-update Bulk update OligoDuplex #

Documentation

Specifications

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OpenAPI Specification

benchling-oligoduplex-api-openapi.yml Raw ↑
openapi: 3.2.0
info:
  license:
    name: Apache 2.0
    url: http://www.apache.org/licenses/LICENSE-2.0.html
  title: Benchling Oligo Duplex API
  version: 2.0.0
  description: 'An oligo duplex is a therapeutic modality consisting of two complementary

    oligonucleotide strands (forward and reverse) with optional conjugate molecules

    attached to either strand.'
servers:
- url: /api/v3
security:
- oAuth: []
- basicApiKeyAuth: []
tags:


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# Full source: https://raw.githubusercontent.com/api-evangelist/benchling/refs/heads/main/openapi/benchling-oligoduplex-api-openapi.yml