# Zetagen Therapeutics

**Canonical:** https://apis.io/providers/zetagen-therapeutics/  
**Website:** https://zetagen.com/  
**APIs profiled:** 9

Zetagen Therapeutics is a private, clinical-stage biopharmaceutical company founded in 2015 and based in Syracuse, New York, where it has operated from laboratory space in the Central New York Biotech Accelerator at SUNY Upstate Medical University since 2017. It develops locally administered small-molecule therapies for metastatic and primary cancers to bone and other organs, built on a proprietary "Zeta" platform derived from the company's discovery of a new molecular pathway acting through the Met5-enkephalin / opioid growth factor receptor signalling axis. Its oncology pipeline includes ZetaMet (Zeta-BC-003) for metastatic breast cancer to bone, which received FDA Breakthrough Device Designation in December 2021 and Health Canada authorisation for a Phase 2a study in January 2022 and reported Phase 2a results at ASCO in June 2026; ZetaMet-P (Zeta-PC-004) for prostate cancer; ZetaMAST (Zeta-MBC-005) for metastatic breast cancer in liver; Zeta-BC-007; and ZetaOnc. Its osteologic programme is ZetaFuse, a synthetic osteoinductive bone graft studied in anterior cervical discectomy and fusion. The company reached 64 worldwide patents in 2024, has been funded by NCI and NIAMS grants, a $5.34M Series A, a $9.79M Series B and an oversubscribed Series B1 closed in November 2025, and its shares trade on secondary markets. Zetagen Therapeutics runs no developer program and publishes no product API, developer portal or API documentation. The only machine-readable surface reachable without credentials is the WordPress REST content API behind zetagen.com, catalogued here.

## Kin Score — 18.8 / 100 (emerging)

Scored 2026-08-12 under rubric 0.11.0. Trend: flat (+0.0 from 18.8).

| Facet | Score |
|---|---|
| Discoverability | 81.5 |
| Contract Quality | 13.5 |
| Governance | 11.5 |
| Operational Transparency | 0.0 |
| Developer Ergonomics | 12.5 |
| Commercial Clarity | 10.5 |

Regulatory layer — **Health**: 26.3 (matched via tags).

## Agent readiness — 30.0 (agent-aware)

| Dimension | Value |
|---|---|
| Spec Presence | yes |
| Agentic Access | no |
| MCP Server | no |
| Auth Clarity | yes |
| Idempotency | no |
| Error Semantics | documented |
| OpenAPI Examples | no |
| Rate Limit Signal | no |
| Event Surface Described | no |
| Agent Skills | derived |
| Well Known Catalog | no |
| Consent Identity | no |
| Agent Card | no |
| Dry Run Mode | no |

## APIs (9)

- **Zetagen Therapeutics Content API** — Posts, pages and the block library.
- **Zetagen Therapeutics Discovery API** — Route index, registered types, taxonomies and statuses.
- **Zetagen Therapeutics Downloads API** — WP Download Manager public search.
- **Zetagen Therapeutics Embed API** — oEmbed 1.0 provider.
- **Zetagen Therapeutics Media API** — The 388-item media library.
- **Zetagen Therapeutics People API** — Author records. Personal data — see x-personal-data. Documented for completeness; deliberately excluded from every packaged Agent Skill in this repo.
- **Zetagen Therapeutics Search API** — Cross-content search.
- **Zetagen Therapeutics Seo API** — Yoast SEO head metadata.
- **Zetagen Therapeutics Taxonomy API** — Categories and tags.

## Security (2)

- **Zetagen Therapeutics Authentication** — 0 schemes
- **Zetagen Therapeutics Domain Security** — TLSv1.3 · DMARC

## Tags

Company, biopharmaceuticals, oncology, bone-health, orthopedics, clinical-trials, life-sciences, drug-development, medical-devices, content-api

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Profiled by [API Evangelist](https://apievangelist.com) and published on [APIs.io](https://apis.io/providers/zetagen-therapeutics/). Scores are computed from the provider's own public artifacts under a published rubric.