# TwinStrand Biosciences

**Canonical:** https://apis.io/providers/twinstrand-biosciences/  
**Website:** https://twinstrandbio.com/  
**APIs profiled:** 12

TwinStrand Biosciences is a Seattle, Washington genomics company founded in 2015 by Jesse Salk and Michael Schmitt that develops and commercializes Duplex Sequencing, an error-corrected next-generation-sequencing chemistry licensed from the University of Washington that independently tracks both strands of an individual DNA molecule and compares them, cutting sequencing error rates from roughly 1-in-100 to below 1-in-10,000,000 per nucleotide and making ultra-rare mutations detectable. The company sells DuplexSeq assay kits — a Mutagenesis Assay for genetic toxicology in human, rat and mouse models, an AML MRD Assay for minimal residual disease in acute myeloid leukemia, and a customizable assay — each paired with a proprietary cloud analysis pipeline that turns raw Illumina reads into duplex-consensus sequences, variant calls, mutation frequency, SBS spectra and assay quality metrics. That analysis software is not a public API: it is hosted on the DNAnexus platform and reachable only by customers through a DNAnexus project. TwinStrand publishes no developer portal, no API reference and no OpenAPI, AsyncAPI, GraphQL or Postman artifact of its own, and the api., docs. and developer. subdomains of twinstrandbio.com do not resolve. The only machine-readable surface on twinstrandbio.com is the WordPress REST API at /wp-json — 349 routes across 18 namespaces — whose wp/v2 content collections are anonymously readable and serve the company publication index, patent estate, conference posters, news releases, events, team profiles, pages and media library as JSON. Its public code lives in the github.com/twinstrandbio organization, which holds a single reference-data repository and no client libraries. The DuplexSeq Mutagenesis Assay business has since been transferred to Scantox, and Exact Sciences holds an exclusive license to the Duplex Sequencing technology.

## Kin Score — 22.3 / 100 (emerging)

Scored 2026-08-12 under rubric 0.11.0. Trend: flat (+0.0 from 22.3).

| Facet | Score |
|---|---|
| Discoverability | 81.5 |
| Contract Quality | 15.1 |
| Governance | 11.5 |
| Operational Transparency | 5.3 |
| Developer Ergonomics | 12.5 |
| Commercial Clarity | 21.1 |

Regulatory layer — **Health**: 31.3 (matched via tags).

## Agent readiness — 26.4 (agent-aware)

| Dimension | Value |
|---|---|
| Spec Presence | yes |
| Agentic Access | no |
| MCP Server | no |
| Auth Clarity | yes |
| Idempotency | no |
| Error Semantics | no |
| OpenAPI Examples | no |
| Rate Limit Signal | no |
| Event Surface Described | no |
| Agent Skills | derived |
| Well Known Catalog | no |
| Consent Identity | no |
| Agent Card | no |
| Dry Run Mode | no |

## APIs (12)

- **TwinStrand Biosciences Discovery API** — The Discovery API from TwinStrand Biosciences — 5 operation(s) for discovery.
- **TwinStrand Biosciences Events API** — The Events API from TwinStrand Biosciences — 2 operation(s) for events.
- **TwinStrand Biosciences Media API** — The Media API from TwinStrand Biosciences — 2 operation(s) for media.
- **TwinStrand Biosciences News API** — The News API from TwinStrand Biosciences — 2 operation(s) for news.
- **TwinStrand Biosciences Pages API** — The Pages API from TwinStrand Biosciences — 2 operation(s) for pages.
- **TwinStrand Biosciences Patents API** — The Patents API from TwinStrand Biosciences — 2 operation(s) for patents.
- **TwinStrand Biosciences People API** — The People API from TwinStrand Biosciences — 4 operation(s) for people.
- **TwinStrand Biosciences Posters API** — The Posters API from TwinStrand Biosciences — 2 operation(s) for posters.
- **TwinStrand Biosciences Posts API** — The Posts API from TwinStrand Biosciences — 2 operation(s) for posts.
- **TwinStrand Biosciences Publications API** — The Publications API from TwinStrand Biosciences — 6 operation(s) for publications.
- **TwinStrand Biosciences Search API** — The Search API from TwinStrand Biosciences — 1 operation(s) for search.
- **TwinStrand Biosciences Taxonomies API** — The Taxonomies API from TwinStrand Biosciences — 4 operation(s) for taxonomies.

## Security (2)

- **Twinstrand Biosciences Authentication** — http · 1 scheme
- **Twinstrand Biosciences Domain Security** — TLSv1.3 · HSTS · DMARC

## Tags

Company, Genomics, Biotechnology, Life Sciences, DNA Sequencing, Next Generation Sequencing, Oncology, Genetic Toxicology, Diagnostics, Bioinformatics, Research, Content

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Profiled by [API Evangelist](https://apievangelist.com) and published on [APIs.io](https://apis.io/providers/twinstrand-biosciences/). Scores are computed from the provider's own public artifacts under a published rubric.