# Tune Therapeutics

**Canonical:** https://apis.io/providers/tune-therapeutics/  
**Website:** https://tunetx.com/  
**APIs profiled:** 1

Tune Therapeutics is a clinical-stage epigenetic editing biotechnology company headquartered in Durham, North Carolina with a second site in Seattle, Washington. Founded in 2021 by Charles Gersbach, Fyodor Urnov and Dan McHugh, the company develops its TEMPO platform for tunable epigenome editing — programmable DNA-binding modulation of gene expression that does not cut or permanently alter the underlying DNA sequence. Its lead program, TUNE-401, is an investigational epigenetic silencing therapy for chronic hepatitis B cleared by New Zealand Medsafe for a Phase 1b trial. Tune publishes no product API and operates no developer program; the only machine-readable surface it exposes is the WordPress REST API and a pair of OAuth-gated Model Context Protocol servers shipped by plugins on its corporate marketing site.

## Kin Score — 22.9 / 100 (emerging)

Scored 2026-08-19 under rubric 0.12.0. Trend: flat (-0.7 from 23.6).

| Facet | Score |
|---|---|
| Discoverability | 75.9 |
| Contract Quality | 0.0 |
| Governance | 18.2 |
| Contract Governance | 18.2 |
| Operational Transparency | 0.0 |
| Developer Ergonomics | 19.0 |
| Commercial Clarity | 21.1 |
| Access Clarity | 21.1 |

Regulatory layer — **Health**: 52.5 (matched via tags).

## Agent readiness — 12.6 (agent-aware)

| Dimension | Value |
|---|---|
| Spec Presence | no |
| Agentic Access | no |
| Reversibility Documented | no |
| MCP Server | documented |
| Auth Clarity | yes |
| Idempotency | no |
| Error Semantics | no |
| OpenAPI Examples | no |
| Rate Limit Signal | no |
| Event Surface Described | no |
| Agent Skills | no |
| Well Known Catalog | no |
| Consent Identity | no |
| Agent Card | no |
| Dry Run Mode | no |

## APIs (1)

- **Tune Therapeutics Website MCP Server** — Two Model Context Protocol servers exposed from the Tune Therapeutics corporate WordPress site via the WordPress MCP Adapter plugin, backed by the WordPress Abilities API. Both ...

## MCP servers (1)

- **tune-therapeutics-mcp.yml**

## Security (2)

- **Tune Therapeutics Authentication** — 2 schemes
- **Tune Therapeutics Domain Security** — TLSv1.3 · HSTS · DMARC

## Tags

Company, Biotechnology, Life Sciences, Therapeutics, Genomics, Epigenetics, Gene Therapy, Clinical Stage, Research

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Profiled by [API Evangelist](https://apievangelist.com) and published on [APIs.io](https://apis.io/providers/tune-therapeutics/). Scores are computed from the provider's own public artifacts under a published rubric.