# Totus Medicines

**Canonical:** https://apis.io/providers/totus-medicines/  
**Website:** https://www.totusmedicines.com/  
**APIs profiled:** 0

Totus Medicines is a biopharmaceutical company developing precision oral medicines against historically "undruggable" disease targets. The company's OmniDEL discovery platform screens targets in their normal cellular environment to identify potent, selective covalent small molecules, drawing on precedents like penicillin and AZT. Totus is advancing a pipeline focused on oncology and immunology & inflammation (I&I), including TOS-358, a covalent PI3Ka inhibitor, and a first-in-class covalent IRF5 inhibitor in clinical development. Headquartered in Emeryville, California, Totus was surfaced as a portfolio company of DCVC and profiled in the API Evangelist network. As a clinical-stage drug-discovery company, Totus publishes no public developer API surface; this profile captures its corporate identity, web properties, and security posture.

## Kin Score — 10.5 / 100 (minimal)

Scored 2026-08-20 under rubric 0.12.0. Trend: flat (+1.1 from 9.4).

| Facet | Score |
|---|---|
| Discoverability | 61.1 |
| Contract Quality | 0.0 |
| Governance | 0.0 |
| Contract Governance | 0.0 |
| Operational Transparency | 10.5 |
| Developer Ergonomics | 4.8 |
| Commercial Clarity | 10.5 |
| Access Clarity | 10.5 |

## Agent readiness — 2.6 (human-only)

| Dimension | Value |
|---|---|
| Spec Presence | no |
| Agentic Access | no |
| Reversibility Documented | no |
| MCP Server | no |
| Auth Clarity | no |
| Idempotency | no |
| Error Semantics | no |
| OpenAPI Examples | no |
| Rate Limit Signal | no |
| Event Surface Described | no |
| Agent Skills | no |
| Well Known Catalog | no |
| Consent Identity | yes |
| Agent Card | no |
| Dry Run Mode | no |

## Access

Unknown — onboarding: unknown, pricing: unknown, trial: no (confidence: low).

## Security (2)

- **Totus Medicines Domain Security** — TLSv1.3 · HSTS · DMARC
- **Totus Medicines Vulnerability Disclosure** — security.txt · contact published

## Tags

Company, Biopharmaceutical, Drug Discovery, Covalent Small Molecules, Oncology, Immunology, Precision Medicine, Biotechnology

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Profiled by [API Evangelist](https://apievangelist.com) and published on [APIs.io](https://apis.io/providers/totus-medicines/). Scores are computed from the provider's own public artifacts under a published rubric.