# Syntis Bio

**Canonical:** https://apis.io/providers/syntis-bio/  
**Website:** https://syntis.bio/  
**APIs profiled:** 0

Syntis Bio is a clinical-stage biopharmaceutical company in Boston, Massachusetts developing oral therapies that use the small intestine as a delivery site. Its SYNT platform (Synthetic Tissue-lining) applies a mussel-inspired polydopamine polymer coating transiently to specific tissues in the GI tract, sustaining therapeutic activity for up to 24 hours before being naturally cleared. The platform is being applied to nutrient exclusion for obesity, gut-restricted enzyme replacement for rare metabolic disorders such as homocystinuria and maple syrup urine disease, and oral bioavailability enhancement for peptides and biologics. Lead candidate SYNT-101 is a once-daily oral pill intended to mimic aspects of gastric bypass by transiently blocking nutrient absorption in the duodenum. The company was co-founded in 2022 by MIT's Robert Langer and Giovanni Traverso with CEO Rahul Dhanda. Syntis Bio is a therapeutics developer and publishes no public API, developer program, SDK, or machine-readable specification.

## Kin Score — 10.3 / 100 (minimal)

Scored 2026-09-02 under rubric 0.18.0. Trend: flat (+0.0 from 10.3).

| Facet | Score |
|---|---|
| Discoverability | 57.4 |
| Contract Quality | 0.0 |
| Governance | 0.0 |
| Contract Governance | 0.0 |
| Operational Transparency | 0.0 |
| Developer Ergonomics | 2.4 |
| Commercial Clarity | 21.1 |
| Access Clarity | 21.1 |

Regulatory layer — **Health**: 17.5 (matched via tags).

## Agent readiness — 0.0 (human-only)

| Dimension | Value |
|---|---|
| Spec Presence | no |
| Agentic Access | no |
| Reversibility Documented | no |
| MCP Server | no |
| Auth Clarity | no |
| Idempotency | no |
| Error Semantics | no |
| OpenAPI Examples | no |
| Rate Limit Signal | no |
| Event Surface Described | no |
| Agent Skills | no |
| Well Known Catalog | no |
| Consent Identity | no |
| Agent Card | no |
| Dry Run Mode | no |
| Delegated Identity | no |
| Protected Resource Metadata | no |
| Dynamic Client Registration | no |
| Agentic Commerce | no |

## Access

Unknown — onboarding: unknown, pricing: unknown, trial: no (confidence: low).

## Security (1)

- **Syntis Bio Domain Security** — TLSv1.3

## Tags

Company, Biotechnology, Pharmaceuticals, Life Sciences, Drug Delivery, Clinical Stage, Obesity, Rare Disease, Health

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Profiled by [API Evangelist](https://apievangelist.com) and published on [APIs.io](https://apis.io/providers/syntis-bio/). Scores are computed from the provider's own public artifacts under a published rubric.