# PineTree Therapeutics

**Canonical:** https://apis.io/providers/pinetree-therapeutics/  
**Website:** https://www.pinetreetx.com/  
**APIs profiled:** 0

Pinetree Therapeutics, Inc. is a preclinical-stage biotechnology company headquartered at West Cambridge Scientific Park, 767C Concord Ave, Cambridge, Massachusetts, developing next-generation targeted protein degraders (TPDs) built on its proprietary AbReptor platform. AbReptor degrades membrane-bound and extracellular proteins through target co-engagement, induced endocytosis, endolysosome formation and lysosomal degradation, aiming to overcome drug resistance and tumor recurrence in oncology, with additional application in inflammation and immunology. The company is advancing trispecific degraders and ADC-integrated programs, closed a $17M Series A in July 2024, and has entered a licensing partnership with AstraZeneca. It is a therapeutics developer rather than a software vendor: it publishes no public API, developer portal, SDK or machine-readable specification.

## Kin Score — 3.3 / 100 (minimal)

Scored 2026-08-19 under rubric 0.12.0. Trend: flat (-2.1 from 5.4).

| Facet | Score |
|---|---|
| Discoverability | 50.0 |
| Contract Quality | 0.0 |
| Governance | 0.0 |
| Contract Governance | 0.0 |
| Operational Transparency | 0.0 |
| Developer Ergonomics | 0.0 |
| Commercial Clarity | 0.0 |
| Access Clarity | 0.0 |

Regulatory layer — **Health**: 7.5 (matched via tags).

## Agent readiness — 0.0 (human-only)

| Dimension | Value |
|---|---|
| Spec Presence | no |
| Agentic Access | no |
| Reversibility Documented | no |
| MCP Server | no |
| Auth Clarity | no |
| Idempotency | no |
| Error Semantics | no |
| OpenAPI Examples | no |
| Rate Limit Signal | no |
| Event Surface Described | no |
| Agent Skills | no |
| Well Known Catalog | no |
| Consent Identity | no |
| Agent Card | no |
| Dry Run Mode | no |

## Security (1)

- **Pinetree Therapeutics Domain Security** — TLSv1.2

## Tags

Company, Biotechnology, Pharmaceuticals, Life Sciences, Oncology, Drug Discovery, Targeted Protein Degradation, Preclinical

---

Profiled by [API Evangelist](https://apievangelist.com) and published on [APIs.io](https://apis.io/providers/pinetree-therapeutics/). Scores are computed from the provider's own public artifacts under a published rubric.