# Orionis Biosciences

**Canonical:** https://apis.io/providers/orionis-biosciences/  
**Website:** https://orionisbio.com/  
**APIs profiled:** 11

Orionis Biosciences is a privately held biotechnology company headquartered at 950 Winter Street in Waltham, Massachusetts, with a research site in Ghent, Belgium, co-founded by Niko Kley and Jan Tavernier. It develops precision medicines across three modalities — small molecule molecular glues built on its Allo-Glue platform, conditional and cis-targeted cytokines built on its A-Kine platform, and multi-specific cell engagers built on its MCE platform — combining disease biology, immunology, chemistry, protein engineering, computational science and machine learning at genome scale. Its lead A-Kine program ORB-011, an attenuated cis-targeted interferon immunotherapy, has entered Phase 1. Orionis has run multi-year molecular-glue discovery collaborations with Genentech (2023, and a 2025 expansion with $105M upfront and more than $2B in potential milestones) and Novartis (from 2020, expanded in 2026 with $40M upfront and up to $1.4B in milestones). Orionis Biosciences publishes no developer program, no product API and no OpenAPI of its own; the only machine-readable surface on orionisbio.com is the WordPress REST API (wp/v2) that serves the company newsroom, corporate and platform pages, leadership and scientific-team profiles and the media library as anonymously readable JSON, alongside a WordPress Abilities API (wp-abilities/v1) registry that is present but authentication-gated.

## Kin Score — 23.0 / 100 (emerging)

Scored 2026-08-17 under rubric 0.11.0. Trend: flat (+0.0 from 23.0).

| Facet | Score |
|---|---|
| Discoverability | 81.5 |
| Contract Quality | 14.4 |
| Governance | 11.5 |
| Operational Transparency | 0.0 |
| Developer Ergonomics | 21.2 |
| Commercial Clarity | 21.1 |

Regulatory layer — **Health**: 31.3 (matched via tags).

## Agent readiness — 38.5 (agent-ready)

| Dimension | Value |
|---|---|
| Spec Presence | yes |
| Agentic Access | derived |
| MCP Server | derived |
| Auth Clarity | yes |
| Idempotency | no |
| Error Semantics | verified |
| OpenAPI Examples | no |
| Rate Limit Signal | no |
| Event Surface Described | no |
| Agent Skills | derived |
| Well Known Catalog | no |
| Consent Identity | no |
| Agent Card | no |
| Dry Run Mode | no |

## APIs (11)

- **Orionis Biosciences Abilities API** — The Abilities API from Orionis Biosciences — 6 operation(s) for abilities.
- **Orionis Biosciences Comments API** — The Comments API from Orionis Biosciences — 2 operation(s) for comments.
- **Orionis Biosciences Discovery API** — The Discovery API from Orionis Biosciences — 8 operation(s) for discovery.
- **Orionis Biosciences Media API** — The Media API from Orionis Biosciences — 4 operation(s) for media.
- **Orionis Biosciences News API** — The News API from Orionis Biosciences — 2 operation(s) for news.
- **Orionis Biosciences O Embed API** — The oEmbed API from Orionis Biosciences — 3 operation(s) for oembed.
- **Orionis Biosciences Pages API** — The Pages API from Orionis Biosciences — 2 operation(s) for pages.
- **Orionis Biosciences Search API** — The Search API from Orionis Biosciences — 1 operation(s) for search.
- **Orionis Biosciences Taxonomy API** — The Taxonomy API from Orionis Biosciences — 4 operation(s) for taxonomy.
- **Orionis Biosciences Team API** — The Team API from Orionis Biosciences — 2 operation(s) for team.
- **Orionis Biosciences Users API** — The Users API from Orionis Biosciences — 3 operation(s) for users.

## MCP servers (1)

- **orionis-biosciences-mcp.yml**

## Agentic access (1)

- **Orionis Biosciences Agentic Access** — 85 operations · 50 acting

## Security (2)

- **Orionis Biosciences Authentication** — apiKey/http · 2 schemes
- **Orionis Biosciences Domain Security** — TLSv1.3 · DMARC

## Tags

Company, Biotechnology, Life Sciences, Drug Discovery, Pharmaceuticals, Oncology, Immunotherapy, Protein Engineering, Molecular Glues, Computational Biology, Machine Learning, Clinical Trials, Content

---

Profiled by [API Evangelist](https://apievangelist.com) and published on [APIs.io](https://apis.io/providers/orionis-biosciences/). Scores are computed from the provider's own public artifacts under a published rubric.
