# Metagenomi

**Canonical:** https://apis.io/providers/metagenomi/  
**Website:** https://metagenomi.co/  
**APIs profiled:** 0

Metagenomi Therapeutics, Inc. (Nasdaq: MGX) is an Emeryville, California clinical-stage genetic medicines company that mines metagenomics — DNA sequenced directly from environmental microbial communities — together with machine learning to discover novel gene-editing machinery from otherwise unknown organisms, then engineers it into in vivo genome-editing therapies. Its published toolbox spans five system classes: programmable CRISPR nucleases, ultra-small nucleases that package into a single AAV vector, base editors the company describes as "the smallest CRISPR base editors known", RNA Mediated Integration Systems (RIGS) for template-encoded edits, and CRISPR Associated Transposases (CASTs) for gene integrations exceeding 10,000 base pairs. The company completed its initial public offering on the Nasdaq Global Select Market in February 2024 at $15.00 per share and partners with Ionis Pharmaceuticals on gene-editing programs including ApoC-III, transthyretin (TTR) and angiotensinogen (AGT). Metagenomi sells therapeutics, not software: metagenomi.co is a seven-page Craft CMS marketing site with no developer program, no API, no SDK and no machine-readable specification of any kind. Its GitHub organization is real and first-party but publishes zero public repositories, and its only first-party software package — the `metagenomi` PyPI library of internal Docker helper scripts — has not shipped a release since July 2019.

## Kin Score — 9.9 / 100 (minimal)

Scored 2026-09-02 under rubric 0.18.0. Trend: flat (+0.0 from 9.9).

| Facet | Score |
|---|---|
| Discoverability | 50.0 |
| Contract Quality | 0.0 |
| Governance | 0.0 |
| Contract Governance | 0.0 |
| Operational Transparency | 2.6 |
| Developer Ergonomics | 2.4 |
| Commercial Clarity | 21.1 |
| Access Clarity | 21.1 |

Regulatory layer — **Health**: 17.5 (matched via tags).

## Agent readiness — 0.0 (human-only)

| Dimension | Value |
|---|---|
| Spec Presence | no |
| Agentic Access | no |
| Reversibility Documented | no |
| MCP Server | no |
| Auth Clarity | no |
| Idempotency | no |
| Error Semantics | no |
| OpenAPI Examples | no |
| Rate Limit Signal | no |
| Event Surface Described | no |
| Agent Skills | no |
| Well Known Catalog | no |
| Consent Identity | no |
| Agent Card | no |
| Dry Run Mode | no |
| Delegated Identity | no |
| Protected Resource Metadata | no |
| Dynamic Client Registration | no |
| Agentic Commerce | no |

## Access

Unknown — onboarding: unknown, pricing: unknown, trial: no (confidence: low).

## Security (1)

- **Metagenomi Domain Security** — TLSv1.3 · HSTS · DMARC

## Tags

Company, Biotechnology, Pharmaceuticals, Gene Editing, CRISPR, Genetic Medicine, Genomics, Drug Discovery, Life Sciences, Machine-Learning, Metagenomics, Research

---

Profiled by [API Evangelist](https://apievangelist.com) and published on [APIs.io](https://apis.io/providers/metagenomi/). Scores are computed from the provider's own public artifacts under a published rubric.