# Kyoto Encyclopedia of Genes and Genomes (KEGG)

**Canonical:** https://apis.io/providers/kegg/  
**Website:** https://www.kegg.jp/kegg/rest/  
**APIs profiled:** 8

The Kyoto Encyclopedia of Genes and Genomes (KEGG) is an integrated database resource for understanding high-level functions and utilities of biological systems from molecular-level information derived from genome sequencing and other high-throughput experiments. The KEGG REST API at rest.kegg.jp provides programmatic access to KEGG databases covering biological pathways, metabolic networks, molecular interactions, drug targets, disease associations, chemical compounds, genomic sequences, and functional orthologs across thousands of organisms. The API exposes seven core operations — info, list, find, get, conv, link, and ddi — enabling identifier conversion, cross-database linking, keyword and structure searches, and full entry retrieval in text, KGML, and JSON formats. Academic use is free via the REST API; FTP and commercial access require subscriptions managed through NPO Bioinformatics Japan and Pathway Solutions.

## Kin Score — 30.5 / 100 (thin)

Scored 2026-08-25 under rubric 0.14.0. Trend: flat (+0.0 from 30.5).

| Facet | Score |
|---|---|
| Discoverability | 81.5 |
| Contract Quality | 53.7 |
| Governance | 0.0 |
| Contract Governance | 0.0 |
| Operational Transparency | 21.1 |
| Developer Ergonomics | 0.0 |
| Commercial Clarity | 39.5 |
| Access Clarity | 39.5 |

Regulatory layer — **Health**: 7.5 (matched via tags).

## Agent readiness — 25.8 (agent-aware)

| Dimension | Value |
|---|---|
| Spec Presence | yes |
| Agentic Access | derived |
| Reversibility Documented | na |
| MCP Server | no |
| Auth Clarity | no |
| Idempotency | na |
| Error Semantics | no |
| OpenAPI Examples | verified |
| Rate Limit Signal | documented |
| Event Surface Described | no |
| Agent Skills | no |
| Well Known Catalog | no |
| Consent Identity | no |
| Agent Card | no |
| Dry Run Mode | na |
| Delegated Identity | no |
| Protected Resource Metadata | no |
| Dynamic Client Registration | no |
| Agentic Commerce | no |

## Access

Freemium — onboarding: unknown, pricing: freemium, trial: no (confidence: medium).

## APIs (8)

- **KEGG REST API** — The KEGG REST API provides unified programmatic access to all KEGG databases through seven operations: INFO (database statistics and release notes), LIST (entry identifiers and ...
- **Kyoto Encyclopedia of Genes and Genomes (KEGG) conv API** — Convert identifiers between KEGG and external databases
- **Kyoto Encyclopedia of Genes and Genomes (KEGG) ddi API** — Find adverse drug-drug interactions
- **Kyoto Encyclopedia of Genes and Genomes (KEGG) find API** — Search entries by keyword or molecular property
- **Kyoto Encyclopedia of Genes and Genomes (KEGG) get API** — Retrieve specific database entries
- **Kyoto Encyclopedia of Genes and Genomes (KEGG) info API** — Display database release information and statistics
- **Kyoto Encyclopedia of Genes and Genomes (KEGG) link API** — Find related entries using database cross-references
- **Kyoto Encyclopedia of Genes and Genomes (KEGG) list API** — Obtain a list of entry identifiers and associated names

## Agentic access (1)

- **Kegg Agentic Access** — 13 operations

## Security (1)

- **Kegg Domain Security** — TLSv1.2

## Plans (1)

- **Kegg Rest Api**

## Tags

Bioinformatics, Genomics, Life Sciences, Pathways, Metabolomics, Drug Targets, Disease, Chemical Compounds, Enzymes, Orthology

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Profiled by [API Evangelist](https://apievangelist.com) and published on [APIs.io](https://apis.io/providers/kegg/). Scores are computed from the provider's own public artifacts under a published rubric.