# Imbria Pharmaceuticals

**Canonical:** https://apis.io/providers/imbria-pharmaceuticals/  
**Website:** https://imbria.com/  
**APIs profiled:** 0

Imbria Pharmaceuticals is a private, clinical-stage biopharmaceutical company based in the Boston area that is developing novel cardiovascular therapies targeting cardiac energy metabolism. Its lead candidate, ninerafaxstat, is a first-in-class partial fatty acid oxidation (pFOX) inhibitor designed to shift myocardial substrate utilization toward glucose oxidation, generating more ATP per unit of oxygen consumed and improving cardiac metabolic efficiency without affecting heart rate, rhythm, ejection fraction or blood pressure. Ninerafaxstat is in the global FORTITUDE-HCM Phase 2b trial (NCT07023614) for symptomatic non-obstructive hypertrophic cardiomyopathy (nHCM), which has no approved treatments, and holds FDA Orphan Drug Designation for that indication; a Phase 2b in cardiometabolic HFpEF is planned. The company is backed by RA Capital, SV Health Investors, Deep Track Capital, Catalio Capital Management, AN Ventures and Cytokinetics. Imbria is a therapeutics developer, not a software vendor, and publishes no public API, developer portal, SDK or machine-readable API contract.

## Kin Score — 11.2 / 100 (emerging)

Scored 2026-08-25 under rubric 0.14.0. Trend: flat (+0.0 from 11.2).

| Facet | Score |
|---|---|
| Discoverability | 57.4 |
| Contract Quality | 0.0 |
| Governance | 0.0 |
| Contract Governance | 0.0 |
| Operational Transparency | 0.0 |
| Developer Ergonomics | 7.1 |
| Commercial Clarity | 21.1 |
| Access Clarity | 21.1 |

Regulatory layer — **Health**: 17.5 (matched via tags).

## Agent readiness — 0.0 (human-only)

| Dimension | Value |
|---|---|
| Spec Presence | no |
| Agentic Access | no |
| Reversibility Documented | no |
| MCP Server | no |
| Auth Clarity | no |
| Idempotency | no |
| Error Semantics | no |
| OpenAPI Examples | no |
| Rate Limit Signal | no |
| Event Surface Described | no |
| Agent Skills | no |
| Well Known Catalog | no |
| Consent Identity | no |
| Agent Card | no |
| Dry Run Mode | no |
| Delegated Identity | no |
| Protected Resource Metadata | no |
| Dynamic Client Registration | no |
| Agentic Commerce | no |

## Security (1)

- **Imbria Pharmaceuticals Domain Security** — TLSv1.3 · HSTS · DMARC

## Tags

Company, Pharmaceuticals, Biotechnology, Life Sciences, Cardiovascular, Clinical Trials, Drug Development, Healthcare, Therapeutics

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Profiled by [API Evangelist](https://apievangelist.com) and published on [APIs.io](https://apis.io/providers/imbria-pharmaceuticals/). Scores are computed from the provider's own public artifacts under a published rubric.