# Entact Bio

**Canonical:** https://apis.io/providers/entactbio/  
**Website:** https://entactbio.com/  
**APIs profiled:** 0

Entact Bio is a preclinical-stage biotechnology company based in Watertown, Massachusetts, developing a new class of small-molecule precision medicines called Enhancement-Targeting Chimeric (ENTAC) molecules. Where targeted protein degradation removes disease-causing proteins, Entact Bio works in the opposite direction: its ENTAC molecules recruit deubiquitinases (DUBs) to strip ubiquitin chains from beneficial proteins in order to extend their half-life, relocate them, or otherwise restore their function. The company's proprietary Encompass platform combines biological, chemical, and computational tools to identify disease targets amenable to protein enhancement across oncology, autoimmune disease, and rare genetic disorders. Entact Bio launched in December 2022 with an $81 million Series A co-led by Qiming Venture Partners USA and venBio Partners, with participation from Abingworth, Brandon Capital, and others. It is a therapeutics research organization and publishes no public developer program, API, or machine-readable API artifacts.

## Kin Score — 5.7 / 100 (minimal)

Scored 2026-08-17 under rubric 0.11.0. Trend: flat (+0.0 from 5.7).

| Facet | Score |
|---|---|
| Discoverability | 53.7 |
| Contract Quality | 0.0 |
| Governance | 0.0 |
| Operational Transparency | 0.0 |
| Developer Ergonomics | 0.0 |
| Commercial Clarity | 0.0 |

Regulatory layer — **Health**: 7.5 (matched via tags).

## Agent readiness — 0.0 (human-only)

| Dimension | Value |
|---|---|
| Spec Presence | no |
| Agentic Access | no |
| MCP Server | no |
| Auth Clarity | no |
| Idempotency | no |
| Error Semantics | no |
| OpenAPI Examples | no |
| Rate Limit Signal | no |
| Event Surface Described | no |
| Agent Skills | no |
| Well Known Catalog | no |
| Consent Identity | no |
| Agent Card | no |
| Dry Run Mode | no |

## Security (1)

- **Entactbio Domain Security** — TLSv1.3 · DMARC

## Tags

Company, Biotechnology, Pharmaceuticals, Drug Discovery, Life Sciences, Targeted Protein Degradation, Preclinical

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Profiled by [API Evangelist](https://apievangelist.com) and published on [APIs.io](https://apis.io/providers/entactbio/). Scores are computed from the provider's own public artifacts under a published rubric.