# Dyno

**Canonical:** https://apis.io/providers/dyno/  
**Website:** https://www.dynotx.com  
**APIs profiled:** 1

Dyno Therapeutics is an AI and biotechnology company building high-performance gene delivery technologies to unlock the potential of next-generation genetic medicine. Using its CapsidMap platform, which combines machine learning with high-throughput in vivo measurement, Dyno designs novel adeno-associated virus (AAV) capsids with improved tissue targeting, immune evasion, manufacturability, and payload capacity. Alongside its capsid partnerships, Dyno operates a public developer platform — Dyno Psi-Phi at design.dynotx.com — that exposes a REST API for agentic protein design: submit structure-prediction, inverse-folding and binder-scoring jobs against GPU-backed open models (AlphaFold2, ESMFold, ProteinMPNN, Boltz, ESM-2, RFDiffusion3, BoltzGen, OpenFold3), track job status, and retrieve scored results. The platform ships a first-party Python CLI (dyno-phi), an MIT-licensed open-source repository, and a provider-published Claude Code Agent Skill. Founded on research from George Church's lab at Harvard, Dyno is headquartered in Watertown, Massachusetts, and is an a16z Bio+Health portfolio company.

## Kin Score — 50.8 / 100 (developing)

Scored 2026-08-20 under rubric 0.12.0. Trend: flat (+0.0 from 50.8).

| Facet | Score |
|---|---|
| Discoverability | 75.9 |
| Contract Quality | 51.7 |
| Governance | 16.7 |
| Contract Governance | 16.7 |
| Operational Transparency | 18.4 |
| Developer Ergonomics | 85.7 |
| Commercial Clarity | 34.2 |
| Access Clarity | 34.2 |

Regulatory layer — **Health**: 31.3 (matched via tags).

## Agent readiness — 38.0 (agent-ready)

| Dimension | Value |
|---|---|
| Spec Presence | yes |
| Agentic Access | no |
| Reversibility Documented | no |
| MCP Server | no |
| Auth Clarity | yes |
| Idempotency | no |
| Error Semantics | verified |
| OpenAPI Examples | no |
| Rate Limit Signal | documented |
| Event Surface Described | no |
| Agent Skills | yes |
| Well Known Catalog | no |
| Consent Identity | no |
| Agent Card | no |
| Dry Run Mode | no |

## Access

Self-service signup, API key from dashboard — onboarding: unknown, pricing: unknown, trial: yes (confidence: medium).

## APIs (1)

- **Dyno Phi — Protein Design API** — Phi is a biomodal computation platform for protein design. The REST API lets a caller create datasets from PDB/CIF structures, submit structure-prediction and sequence-design jo...

## MCP servers (1)

- **Dyno MCP Server** — Dyno publishes NO MCP server. This file is an API Evangelist CANDIDATE tool surface derived from the provider's OpenAPI, offered as a design sketch — it is NOT wired as a type: ...

## Security (2)

- **Dyno Authentication** — apiKey/http-bearer/oidc-session · 3 schemes
- **Dyno Domain Security** — TLSv1.3 · HSTS · DMARC

## Plans (1)

- **Dyno Plans Pricing**

## Tags

Company, Biotechnology, Gene Therapy, Genetic Medicine, Gene Delivery, AAV Capsid, Artificial Intelligence, Machine-Learning, Drug Discovery, Healthcare, Protein Design, Protein Structure Prediction, Bioinformatics, Computational Biology, Agentic AI, Life Sciences

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Profiled by [API Evangelist](https://apievangelist.com) and published on [APIs.io](https://apis.io/providers/dyno/). Scores are computed from the provider's own public artifacts under a published rubric.