# Cradle

**Canonical:** https://apis.io/providers/cradle-bio/  
**Website:** https://www.cradle.bio  
**APIs profiled:** 1

Cradle is a Dutch–Swiss biotechnology software company founded in 2021 with headquarters in Amsterdam and an office in Zurich, building an AI-powered protein engineering platform for industrial biotech and biopharma R&D teams. The platform combines proprietary generative AI models — trained on billions of natural protein sequences and on data produced in Cradle's own Amsterdam wet lab — with a web application and REST API/Python SDK so that scientists can design, simulate, and co-optimize amino-acid sequence variants across multiple measurable properties such as activity, binding affinity, stability, expression, and developability. Core platform capabilities include AI candidate generation, multi-property co-optimization, virtual plate design, experimental data management with full versioning and audit trails, task orchestration (analyze data, diversify, engineer, select, search, train) across modalities including antibodies/mAbs, enzymes, vaccines, therapeutic peptides, and food ingredients, plus a Custom Predictors framework letting customers plug in their own ML models. Cradle is sold as enterprise SaaS to R&D organizations — disclosed customers and partners include Johnson & Johnson Janssen, Bayer, Novozymes/Novonesis, and Twist Bioscience, with the platform serving six of the top 25 global pharma companies and over 50 active R&D programs. The company has raised approximately $115M to date across a seed round (Index Ventures, 2022), a $24M Series A (Index Ventures, 2023), and a $73M Series B (IVP, 2024). Co-founders are Stef van Grieken (CEO), Jelle Prins, Elise de Reus, Eli Bixby, and Harmen van Rossum.

## Kin Score — 8.8 / 100 (minimal)

Scored 2026-08-25 under rubric 0.14.0. Trend: flat (+0.0 from 8.8).

| Facet | Score |
|---|---|
| Discoverability | 68.5 |
| Contract Quality | 0.0 |
| Governance | 0.0 |
| Contract Governance | 0.0 |
| Operational Transparency | 13.2 |
| Developer Ergonomics | 9.5 |
| Commercial Clarity | 0.0 |
| Access Clarity | 0.0 |

Regulatory layer — **Health**: 7.5 (matched via tags).

## Agent readiness — 0.0 (human-only)

| Dimension | Value |
|---|---|
| Spec Presence | no |
| Agentic Access | no |
| Reversibility Documented | no |
| MCP Server | no |
| Auth Clarity | no |
| Idempotency | no |
| Error Semantics | no |
| OpenAPI Examples | no |
| Rate Limit Signal | no |
| Event Surface Described | no |
| Agent Skills | no |
| Well Known Catalog | no |
| Consent Identity | no |
| Agent Card | no |
| Dry Run Mode | no |
| Delegated Identity | no |
| Protected Resource Metadata | no |
| Dynamic Client Registration | no |
| Agentic Commerce | no |

## Access

Unknown — onboarding: unknown, pricing: unknown, trial: no (confidence: low).

## APIs (1)

- **Cradle Platform API** — The Cradle Platform API is an enterprise REST API for programmatic access to Cradle's AI-driven protein engineering platform. It is organized under per-workspace v2 endpoints an...

## Security (1)

- **Cradle Bio Domain Security** — TLSv1.3 · HSTS · DNSSEC · DMARC

## Tags

Protein Engineering, Generative Biology, Generative AI, Foundation Models, Machine-Learning, Biotechnology, Biopharma, Drug Discovery, Antibody Discovery, Enzyme Engineering, Vaccines, Therapeutic Peptides, Industrial Biotech, Synthetic Biology, Computational Biology, Wet Lab, Life Sciences, Custom Predictors

---

Profiled by [API Evangelist](https://apievangelist.com) and published on [APIs.io](https://apis.io/providers/cradle-bio/). Scores are computed from the provider's own public artifacts under a published rubric.