# ChEMBL

**Canonical:** https://apis.io/providers/chembl/  
**Website:** https://www.ebi.ac.uk/chembl/  
**APIs profiled:** 16

ChEMBL is a manually curated database of bioactive molecules with drug-like properties, maintained by the EMBL-EBI. It provides a REST API for accessing bioactive molecules, drug targets, bioactivity data, approved drugs, clinical trial compounds, and cheminformatics utilities to support drug discovery research.

## Kin Score — 32.5 / 100 (thin)

Scored 2026-08-20 under rubric 0.12.0. Trend: flat (+0.0 from 32.5).

| Facet | Score |
|---|---|
| Discoverability | 81.5 |
| Contract Quality | 50.7 |
| Governance | 9.8 |
| Contract Governance | 9.8 |
| Operational Transparency | 0.0 |
| Developer Ergonomics | 11.9 |
| Commercial Clarity | 39.5 |
| Access Clarity | 39.5 |

Regulatory layer — **Health**: 20.0 (matched via tags).

## Agent readiness — 34.7 (agent-ready)

| Dimension | Value |
|---|---|
| Spec Presence | yes |
| Agentic Access | derived |
| Reversibility Documented | na |
| MCP Server | no |
| Auth Clarity | yes |
| Idempotency | na |
| Error Semantics | no |
| OpenAPI Examples | no |
| Rate Limit Signal | documented |
| Event Surface Described | no |
| Agent Skills | no |
| Well Known Catalog | no |
| Consent Identity | no |
| Agent Card | no |
| Dry Run Mode | na |

## Access

Free — onboarding: unknown, pricing: free, trial: no (confidence: medium).

## APIs (16)

- **ChEMBL Activity API** — Activity values recorded in assays, linking molecules to targets with quantitative bioactivity measurements.
- **ChEMBL Assay API** — Experimental protocols and result details from source documents and datasets.
- **ChEMBL ATC Classification API** — WHO Anatomical Therapeutic Chemical classification for drugs.
- **ChEMBL Binding Site API** — Target binding site definitions used in assays.
- **ChEMBL Cell Line API** — Cell line information used in assays.
- **ChEMBL Compound Record API** — Occurrence of a compound in a specific source document.
- **ChEMBL Document API** — Source documents and datasets from which assay data is derived.
- **ChEMBL Drug API** — Approved drug information including applicants, patent numbers, and research codes.
- **ChEMBL Drug Indication API** — Drug-disease associations with clinical trial and regulatory references.
- **ChEMBL Drug Warning API** — Safety information for withdrawn or black-box warned drugs.
- **ChEMBL Mechanism API** — Mechanism of action information for approved drugs.
- **ChEMBL Molecule API** — Chemical molecules including properties, structural representations, synonyms, and drug-like properties.
- **ChEMBL Similarity API** — Molecule similarity searching using Tanimoto coefficient.
- **ChEMBL Status API** — API operational status and ChEMBL database version information.
- **ChEMBL Substructure API** — Molecular substructure searching.
- **ChEMBL Target API** — Protein and non-protein targets defined in assays.

## Agentic access (1)

- **Chembl Agentic Access** — 30 operations

## Security (1)

- **Chembl Domain Security** — TLSv1.3 · HSTS · DMARC

## Plans (1)

- **Plans**

## Tags

Drug Discovery, Bioactivity, Molecules, Cheminformatics, Life Sciences, Bioinformatics, Pharmacology, EMBL-EBI

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Profiled by [API Evangelist](https://apievangelist.com) and published on [APIs.io](https://apis.io/providers/chembl/). Scores are computed from the provider's own public artifacts under a published rubric.