# Boltz

**Canonical:** https://apis.io/providers/boltz/  
**Website:** https://boltz.bio  
**APIs profiled:** 7

Boltz (Boltz PBC) is a public-benefit AI research company building open-source and proprietary foundation models for biomolecular structure prediction, binding-affinity estimation, and generative protein and small-molecule design. Its open-source models (Boltz-1, Boltz-2, BoltzGen, all MIT-licensed) are used by 100,000+ scientists across pharma and biotech, and its commercial platform, Boltz Lab, pairs those models with managed compute and collaborative interfaces. The Boltz Compute API exposes these capabilities as asynchronous jobs - structure & binding prediction, ADME prediction, and small-molecule / protein design and library screening - with official Python, TypeScript, and Go SDKs, a CLI, and an MCP server for agentic drug-discovery workflows. Backed by a $28M seed round led by Amplify Partners, a16z, and Zetta Venture Partners.

## Kin Score — 50.8 / 100 (developing)

Scored 2026-08-17 under rubric 0.11.0. Trend: flat (+0.0 from 50.8).

| Facet | Score |
|---|---|
| Discoverability | 81.5 |
| Contract Quality | 58.2 |
| Governance | 3.1 |
| Operational Transparency | 36.8 |
| Developer Ergonomics | 87.0 |
| Commercial Clarity | 44.7 |

Regulatory layer — **Health**: 31.3 (matched via tags).

## Agent readiness — 44.1 (agent-ready)

| Dimension | Value |
|---|---|
| Spec Presence | yes |
| Agentic Access | no |
| MCP Server | yes |
| Auth Clarity | yes |
| Idempotency | no |
| Error Semantics | documented |
| OpenAPI Examples | no |
| Rate Limit Signal | no |
| Event Surface Described | no |
| Agent Skills | yes |
| Well Known Catalog | no |
| Consent Identity | no |
| Agent Card | no |
| Dry Run Mode | no |

## Access

Self-serve signup — onboarding: self-serve, pricing: unknown, trial: no (confidence: medium).

## APIs (7)

- **Boltz Admin API** — The Admin API from Boltz — 7 operation(s) for admin.
- **Boltz Auth API** — The Auth API from Boltz — 1 operation(s) for auth.
- **Boltz CLI API** — The CLI API from Boltz — 1 operation(s) for cli.
- **Boltz Predictions API** — The Predictions API from Boltz — 8 operation(s) for predictions.
- **Boltz Protein API** — The Protein API from Boltz — 15 operation(s) for protein.
- **Boltz Share Links API** — The Share Links API from Boltz — 4 operation(s) for share links.
- **Boltz Small Molecule API** — The Small Molecule API from Boltz — 14 operation(s) for small molecule.

## MCP servers (1)

- **boltz-mcp.yml**

## Security (2)

- **Boltz Authentication** — 1 scheme
- **Boltz Domain Security** — TLSv1.3 · DMARC

## Tags

Company, Digital Biology, Drug Discovery, Artificial Intelligence, Machine Learning, Protein Design, Structure Prediction, Life Sciences, Compute

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Profiled by [API Evangelist](https://apievangelist.com) and published on [APIs.io](https://apis.io/providers/boltz/). Scores are computed from the provider's own public artifacts under a published rubric.