# Bitterroot Bio

**Canonical:** https://apis.io/providers/bitterroot-bio/  
**Website:** https://brbio.com  
**APIs profiled:** 0

Bitterroot Bio is a privately held, clinical-stage biotechnology company based in Palo Alto, California, pioneering the emerging field of cardio-immunology — the interplay between the immune system and cardiovascular disease. Its lead program, BRB-002, is a novel investigational immunomodulating protein therapy that targets CD47 to treat atherosclerotic cardiovascular disease (ASCVD) by acting on atherosclerotic plaque through the immunomodulation of macrophages, an approach distinct from current standards of care. Founded in 2021, the company is advancing BRB-002 through its MATADOR Phase 2a proof-of-concept study. Bitterroot Bio is a therapeutics developer and publishes no public developer API or programmatic surface; this profile captures its public web identity within the API Evangelist network.

## Kin Score — 9.5 / 100 (minimal)

Scored 2026-08-20 under rubric 0.12.0. Trend: flat (+0.0 from 9.5).

| Facet | Score |
|---|---|
| Discoverability | 50.0 |
| Contract Quality | 0.0 |
| Governance | 0.0 |
| Contract Governance | 0.0 |
| Operational Transparency | 0.0 |
| Developer Ergonomics | 2.4 |
| Commercial Clarity | 21.1 |
| Access Clarity | 21.1 |

Regulatory layer — **Health**: 17.5 (matched via tags).

## Agent readiness — 0.0 (human-only)

| Dimension | Value |
|---|---|
| Spec Presence | no |
| Agentic Access | no |
| Reversibility Documented | no |
| MCP Server | no |
| Auth Clarity | no |
| Idempotency | no |
| Error Semantics | no |
| OpenAPI Examples | no |
| Rate Limit Signal | no |
| Event Surface Described | no |
| Agent Skills | no |
| Well Known Catalog | no |
| Consent Identity | no |
| Agent Card | no |
| Dry Run Mode | no |

## Access

Unknown — onboarding: unknown, pricing: unknown, trial: no (confidence: low).

## Security (1)

- **Bitterroot Bio Domain Security** — TLSv1.3 · DMARC

## Tags

Company, Life Sciences, Biotechnology, Cardiovascular, Cardio-Immunology, Pharmaceuticals, Clinical Trials, Drug Development, Palo Alto

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Profiled by [API Evangelist](https://apievangelist.com) and published on [APIs.io](https://apis.io/providers/bitterroot-bio/). Scores are computed from the provider's own public artifacts under a published rubric.