# A-Alpha Bio

**Canonical:** https://apis.io/providers/a-alpha-bio/  
**Website:** https://www.aalphabio.com/  
**APIs profiled:** 1

A-Alpha Bio is a Seattle biotechnology company, founded in 2017 out of the University of Washington's Institute for Protein Design and Center for Synthetic Biology, that measures, predicts and engineers protein-protein interactions. Its experimental platform AlphaSeq reprograms yeast mating to quantify millions of protein-protein binding affinities in a single experiment, and its computational platform AlphaBind is a domain-specific deep-learning model trained on hundreds of millions of those affinity measurements to predict and optimize antibody-antigen binding from sequence. In July 2026 the company launched Atlas, a web platform and data ecosystem that publishes ML-ready protein interaction "Data Blocks" for licensing, custom on-demand data generation, and a quarterly-release Atlas Consortium whose founding members include GSK, Boltz, Cradle and Dyno Therapeutics. Atlas is backed by a public HTTP API — the Data Product API at api.atlas.aalphabio.com — which serves dataset discovery, dataset metadata and structured Data Cards anonymously, and gates CSV data, CSV schemas and structure (.cif) files behind a bearer token issued through AWS Cognito sign-in.

## Kin Score — 39.2 / 100 (thin)

Scored 2026-08-17 under rubric 0.11.0. Trend: flat (+0.0 from 39.2).

| Facet | Score |
|---|---|
| Discoverability | 75.9 |
| Contract Quality | 67.2 |
| Governance | 11.5 |
| Operational Transparency | 5.3 |
| Developer Ergonomics | 36.4 |
| Commercial Clarity | 34.2 |

Regulatory layer — **Health**: 31.3 (matched via tags).

## Agent readiness — 36.3 (agent-ready)

| Dimension | Value |
|---|---|
| Spec Presence | yes |
| Agentic Access | no |
| MCP Server | derived |
| Auth Clarity | yes |
| Idempotency | no |
| Error Semantics | verified |
| OpenAPI Examples | no |
| Rate Limit Signal | no |
| Event Surface Described | no |
| Agent Skills | derived |
| Well Known Catalog | no |
| Consent Identity | no |
| Agent Card | no |
| Dry Run Mode | no |

## APIs (1)

- **A-Alpha Bio Datasets API** — The Datasets API from A-Alpha Bio — 9 operation(s) for datasets.

## MCP servers (1)

- **a-alpha-bio-mcp.yml**

## Security (2)

- **A Alpha Bio Authentication** — http/oauth2 · 2 schemes
- **A Alpha Bio Domain Security** — TLSv1.3 · HSTS · DMARC

## Tags

protein-interactions, biotechnology, drug-discovery, antibody-engineering, synthetic-biology, machine-learning, training-data, data-licensing, life-sciences, datasets, protein-design, bioinformatics

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Profiled by [API Evangelist](https://apievangelist.com) and published on [APIs.io](https://apis.io/providers/a-alpha-bio/). Scores are computed from the provider's own public artifacts under a published rubric.