# UniRef REST API

**Canonical:** https://apis.io/apis/uniprot/uniref-rest-api/  
**Provider:** UniProt — https://apis.io/providers/uniprot/  
**Base URL:** https://rest.uniprot.org/uniref  
**Documentation:** https://www.uniprot.org/help/uniref

UniRef REST API is one of 7 APIs that [UniProt](https://apis.io/providers/uniprot/) publishes on the [APIs.io](https://apis.io/) network. Tagged areas include Proteins, Sequence Clusters, and Redundancy Reduction. The published artifact set on APIs.io includes API documentation.

UniRef (UniProt Reference Clusters) groups similar sequences to reduce redundancy. UniRef100 combines identical sequences; UniRef90 clusters sequences sharing 90% identity; UniRef50 clusters at 50%. The REST API allows searching and retrieving clusters with associated member lists.

## Machine-readable artifacts (2)

- **Documentation** — https://www.uniprot.org/help/uniref
- **TermsOfService** — https://www.uniprot.org/help/license

## Other UniProt APIs (6)

- [UniProtKB REST API](https://apis.io/apis/uniprot/uniprotkb-rest-api/)
- [UniParc REST API](https://apis.io/apis/uniprot/uniparc-rest-api/)
- [Proteomes REST API](https://apis.io/apis/uniprot/proteomes-rest-api/)
- [ID Mapping REST API](https://apis.io/apis/uniprot/id-mapping-rest-api/)
- [UniProt SPARQL Endpoint](https://apis.io/apis/uniprot/uniprot-sparql-endpoint/)
- [EBI Proteins REST API](https://apis.io/apis/uniprot/ebi-proteins-rest-api/)

## Tags

Proteins, Sequence Clusters, Redundancy Reduction

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Profiled by [API Evangelist](https://apievangelist.com) and published on [APIs.io](https://apis.io/apis/uniprot/uniref-rest-api/). The API's provider profile, Kin Score and agent-readiness rating are at https://apis.io/providers/uniprot/.