# Surescripts Real-Time Prescription Benefit

**Canonical:** https://apis.io/apis/surescripts/surescripts-real-time-prescription-benefit-api/  
**Provider:** Surescripts — https://apis.io/providers/surescripts/  
**Documentation:** https://docs.surescripts.com/rtpb/home

Surescripts Real-Time Prescription Benefit is one of 8 APIs that [Surescripts](https://apis.io/providers/surescripts/) publishes on the [APIs.io](https://apis.io/) network. Tagged areas include Real-Time Prescription Benefit, RTPB, Pricing, and Cost Transparency. The published artifact set on APIs.io includes API documentation and an API reference.

Returns patient-specific, real-time out-of-pocket drug cost, coverage status, and therapeutic alternatives at the point of prescribing, as a synchronous RTPBRequest/RTPBResponse pair. Implements the NCPDP Real-Time Prescription Benefit standard v13 XML schema and is exchanged through certified prescriber, pharmacy and PBM/payer systems. Companion guides for provider vendors, pharmacies and PBM/payers are published on the Surescripts Developer Portal; no public REST endpoint or OpenAPI exists.

## Machine-readable artifacts (2)

- **Documentation** — https://docs.surescripts.com/rtpb/home
- **APIReference** — https://docs.surescripts.com/rtpb-providers/guide

## Other Surescripts APIs (7)

- [Surescripts Medication History for Populations FHIR API](https://apis.io/apis/surescripts/surescripts-medication-history-populations-fhir-api/)
- [Surescripts Formulary Download API](https://apis.io/apis/surescripts/surescripts-formulary-download-api/)
- [Surescripts E-Prescribing](https://apis.io/apis/surescripts/surescripts-e-prescribing-api/)
- [Surescripts Eligibility and Formulary](https://apis.io/apis/surescripts/surescripts-eligibility-formulary-api/)
- [Surescripts Electronic Prior Authorization](https://apis.io/apis/surescripts/surescripts-electronic-prior-authorization-api/)
- [Surescripts Clinical Direct Messaging](https://apis.io/apis/surescripts/surescripts-clinical-direct-messaging-api/)
- [Surescripts Record Locator and Exchange](https://apis.io/apis/surescripts/surescripts-record-locator-exchange-api/)

## Tags

Real-Time Prescription Benefit, RTPB, Pricing, Cost Transparency

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Profiled by [API Evangelist](https://apievangelist.com) and published on [APIs.io](https://apis.io/apis/surescripts/surescripts-real-time-prescription-benefit-api/). The API's provider profile, Kin Score and agent-readiness rating are at https://apis.io/providers/surescripts/.