# Ensembl REST API

**Canonical:** https://apis.io/apis/life-sciences/ensembl-rest-api/  
**Provider:** Life Sciences — https://apis.io/providers/life-sciences/  
**Base URL:** https://rest.ensembl.org/  
**Documentation:** https://rest.ensembl.org/

Ensembl REST API is one of 22 APIs that [Life Sciences](https://apis.io/providers/life-sciences/) publishes on the [APIs.io](https://apis.io/) network. This API exposes 1 JSON Schema definition. Tagged areas include Genomics, Variation, VEP, EBI, and GA4GH. The published artifact set on APIs.io includes API documentation and 1 JSON Schema.

The European Bioinformatics Institute's REST/JSON interface to the Ensembl genome browser. Provides programmatic access to genomic annotation, variation, comparative genomics, regulatory data, the Variant Effect Predictor (VEP), and GA4GH-compatible variation endpoints across vertebrate, invertebrate, plant, and fungal genomes.

## Machine-readable artifacts (4)

- **Documentation** — https://rest.ensembl.org/
- **Documentation** — https://rest.ensembl.org/documentation/info/vep_hgvs_get
- **JSONSchema** — https://raw.githubusercontent.com/api-evangelist/life-sciences/refs/heads/main/json-schema/gene-schema.json
- **Examples** — https://raw.githubusercontent.com/api-evangelist/life-sciences/refs/heads/main/examples/gene-example.json

## Other Life Sciences APIs (12)

- [EU Clinical Trials Register / CTIS](https://apis.io/apis/life-sciences/eu-clinical-trials-register-ctis/)
- [openFDA](https://apis.io/apis/life-sciences/openfda/)
- [DailyMed](https://apis.io/apis/life-sciences/dailymed/)
- [RxNorm API](https://apis.io/apis/life-sciences/rxnorm-api/)
- [DrugBank API](https://apis.io/apis/life-sciences/drugbank-api/)
- [NCBI Entrez E-utilities](https://apis.io/apis/life-sciences/ncbi-entrez-e-utilities/)
- [UCSC Genome Browser REST API](https://apis.io/apis/life-sciences/ucsc-genome-browser-rest-api/)
- [ClinVar (via E-utilities)](https://apis.io/apis/life-sciences/clinvar-via-e-utilities/)
- [dbSNP (via E-utilities)](https://apis.io/apis/life-sciences/dbsnp-via-e-utilities/)
- [HL7 FHIR](https://apis.io/apis/life-sciences/hl7-fhir/)
- [SMART on FHIR](https://apis.io/apis/life-sciences/smart-on-fhir/)
- [Benchling Developer Platform](https://apis.io/apis/life-sciences/benchling-developer-platform/)

## Tags

Genomics, Variation, VEP, EBI, GA4GH

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Profiled by [API Evangelist](https://apievangelist.com) and published on [APIs.io](https://apis.io/apis/life-sciences/ensembl-rest-api/). The API's provider profile, Kin Score and agent-readiness rating are at https://apis.io/providers/life-sciences/.