# Orion Molecular Design Platform API

**Canonical:** https://apis.io/apis/cadence/orion/  
**Provider:** Cadence Design Systems — https://apis.io/providers/cadence/  
**Base URL:** https://orion.eyesopen.com  
**Documentation:** https://www.eyesopen.com/orion/platform

Orion Molecular Design Platform API is one of 3 APIs that [Cadence Design Systems](https://apis.io/providers/cadence/) publishes on the [APIs.io](https://apis.io/) network. Tagged areas include Molecular Design, Drug Discovery, Cheminformatics, Scientific Computing, and Cloud Platform. The published artifact set on APIs.io includes API documentation, an API reference, a getting-started guide, authentication docs, and a changelog.

The cloud-native molecular design platform from OpenEye, Cadence Molecular Sciences — the Cadence Design Systems business unit acquired in 2022 (its documentation carries a Cadence Design Systems copyright). Orion runs cube/floe computational workflows, datasets, shard collections, jobs and GPU-backed molecule search. Clients authenticate with an account-issued token; the published interface is the orionclient Python library and the ocli command line interface, and no OpenAPI, GraphQL SDL or AsyncAPI contract is published for it. Base host read from the provider's own documented example ("Url of Orion Stack, ex: orion.eyesopen.com").

## Machine-readable artifacts (8)

- **Documentation** — https://docs.eyesopen.com/orion-developer/index.html
- **APIReference** — https://docs.eyesopen.com/orion-developer/modules/orion-platform/docs/orionclient/cli.html
- **GettingStarted** — https://docs.eyesopen.com/orion-developer/development/intro.html
- **Authentication** — https://raw.githubusercontent.com/api-evangelist/cadence/refs/heads/main/authentication/cadence-authentication.yml
- **CLI** — https://raw.githubusercontent.com/api-evangelist/cadence/refs/heads/main/cli/cadence-cli.yml
- **Conventions** — https://raw.githubusercontent.com/api-evangelist/cadence/refs/heads/main/conventions/cadence-conventions.yml
- **ChangeLog** — https://docs.eyesopen.com/orion-user-interface/releasenotes/index.html
- **SignUp** — https://www.eyesopen.com/orion-signup

## Other Cadence Design Systems APIs (2)

- [Cadence Design Systems](https://apis.io/apis/cadence/cadence-design-systems/)
- [MMDS — Macromolecular Data Service](https://apis.io/apis/cadence/mmds/)

## Tags

Molecular Design, Drug Discovery, Cheminformatics, Scientific Computing, Cloud Platform

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Profiled by [API Evangelist](https://apievangelist.com) and published on [APIs.io](https://apis.io/apis/cadence/orion/). The API's provider profile, Kin Score and agent-readiness rating are at https://apis.io/providers/cadence/.